Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2015 | Invited speaker presentation

Controversies about the role of the deficit of habituation of evoked potentials in migraine: a disease biomarker? PROS

Author: Anna Ambrosini

Published in: The Journal of Headache and Pain | Special Issue 1/2015

Login to get access

Excerpt

In most studies, episodic migraineurs have an interictal habituation deficit of cortical evoked potentials to repeated monotonous stimuli. It has been found by applying almost every modality of sensory stimulation for evoked potentials (visual - VEP, auditory - AEP, somatosensory - SEP), as well as in visual evoked magnetoencephalographic (MEG) responses[1], thus it is considered as a biomarker of the interictal status, which normalises during the migraine attacks and cannot be found in chronic migraine. A reduced habituation deficit, however, was not confirmed in migraineurs in some studies[1], which was attributed to low reliability and repeatability[2, 3], and to a reduced specificity to migraine pathophysiology. …
Literature
1.
de Tommaso M, Ambrosini A, Brighina F, Coppola G, Perrotta A, Pierelli F, Sandrini G, Valeriani M, Marinazzo D, Stramaglia S, Schoenen J: Altered processing of sensory stimuli in patients with migraine. Nat Rev Neurol. 2014, 10: 144-155. 10.1038/nrneurol.2014.14.CrossRefPubMed
2.
Omland PM, Nilsen KB, Uglem M, Gravdahl G, Linde M, Hagen K, Sand T: Visual evoked potentials in interictal migraine: no confirmation of abnormal habituation. Headache. 2013, 53: 1071-1086. 10.1111/head.12006.CrossRefPubMed
3.
Omland PM, Uglem M, Hagen K, Linde M, Tronvik E, Sand T: Visual evoked potentials in migraine: Is the “neurophysiological hallmark” concept still valid?. Clin Neurophysiol. 2015, S1388-2457(15)00627-6-doi: 10.1016/j.clinph.2014.12.035. [Epub ahead of print]
4.
Bednář M, Kubová Z, Kremláček J: Lack of visual evoked potentials amplitude decrement during prolonged reversal and motion stimulation in migraineurs. Clin Neurophysiol. 2014, 125: 1223-1230. 10.1016/j.clinph.2013.10.050.CrossRefPubMed
5.
Ambrosini A, Iezzi E, Perrotta A, Kisialiou A, Nardella A, Berardelli A, Pierelli F, Schoenen J: Correlation between habituation of visual-evoked potentials and magnetophosphene thresholds in migraine: A case-control study. Cephalalgia. 2015, 0333102415590241-[Epub ahead of print]
6.
Ambrosini A, Rossi P, De Pasqua V, Pierelli F, Schoenen J: Lack of habituation causes high intensity dependence of auditory evoked cortical potentials in migraine. Brain. 2003, 126: 2009-2015. 10.1093/brain/awg206.CrossRefPubMed
7.
Ambrosini A, Coppola G, Iezzi E, Pierelli F, Schoenen J: Reliability and repeatability of testing Visual Evoked Potentials in migraine. Abstracts of the 1st European Academy Congress, Berlin (Germany), 20-23 June 2015. Eur J Neurol. 2015, 22 (1): 1120-131.
8.
Brazzo D, Di Lorenzo G, Bill P, Fasce M, Papalia G, Veggiotti P, Seri S: Abnormal visual habituation in pediatric photosensitive epilepsy. Clin Neurophysiol. 2011, 122: 16-20. 10.1016/j.clinph.2010.06.002.CrossRefPubMed
9.
Buonfiglio M, Toscano M, Puledda F, Avanzini G, Di Clemente L, Di Sabato F, Di Piero V: Lack of habituation of evoked visual potentials in analytic information processing style: evidence in healthy subjects. Neurol Sci. 2015, 36: 391-395. 10.1007/s10072-014-1962-7.CrossRefPubMed
10.
Di Sabato F, Buonfiglio M, Mandillo S: Analytic information processing style in migraineurs. Neurol Sci. 2013, 34: 1145-1150. 10.1007/s10072-012-1193-8.CrossRefPubMed
11.
Ambrosini A, Coppola G, Gérardy PY, Pierelli F, Schoenen J: Intensity dependence of auditory evoked potentials during light interference in migraine. Neurosci Lett. 2011, 492: 80-83. 10.1016/j.neulet.2011.01.060.CrossRefPubMed
12.
Ambrosini A, Kisialiou A, Finos L, Afra J, Coppola G, Di Clemente L, Iezzi E, Magis D, Sandor PS, Sasso D'Elia T, Viganò A, Fataki M, Pierelli F, Schoenen J: The diagnostic value of Visual and Auditory Evoked Potentials in migraine: a retrospective multicenter study. Abstracts of the 2013 International Headache Congress, Boston, MA (USA), 27-30 June, 2013. Cephalalgia. 2013, 33 (Suppl 8): 213-153.
Metadata
Title
Controversies about the role of the deficit of habituation of evoked potentials in migraine: a disease biomarker? PROS
Author
Anna Ambrosini
Publication date
01-12-2015
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-16-S1-A14

Other articles of this Special Issue 1/2015

The Journal of Headache and Pain 1/2015 Go to the issue

Poster presentation

P003. NSAIDs for symptomatic treatment of headache

Oral presentation

O033. TDCs treatment: long term results in drug resistant migrainous patients

Poster presentation

P063. Colloid cysts of the third ventricle: a case report

Poster presentation

P071. Headache self-administered questionnaire in the waiting room, a useful and easy tool for headache centres

Poster presentation

P057. Prophylaxis with low-dose methadone in patients affected by daily refractory headache and medication-overuse headache: a prospective cohort study (METACEF study)

Oral presentation

O047. The sound-induced flash illusions reveal visual cortex hyperexcitability in cluster headache