Published in:
Open Access
01-12-2015 | Commentary
Migraine and hemorrhagic stroke: data from general practice
Authors:
Raffaele Ornello, Francesca Pistoia, Diana Degan, Antonio Carolei, Simona Sacco
Published in:
The Journal of Headache and Pain
|
Issue 1/2015
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Excerpt
Migraine is one of the most disabling headache disorders and the seventh most disabling disease worldwide [
1]. Several epidemiological studies have investigated the association between migraine and vascular disease [
2]. Two meta-analyses found a clear increase in the risk of ischemic stroke in subjects with migraine, mostly migraine with aura (MA), as compared with non-migraineurs [
3,
4]. Another meta-analysis found an increased risk of hemorrhagic stroke (HS) in subjects with migraine [
5], although potential sources of heterogeneity can be found among the studies included in that analysis. Most studies did not distinguish between intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) when assessing the outcomes and some of them did not report the outcomes separately for MA and migraine without aura (MO). In addition, in the available studies little consideration was given to migraine activity and duration. …