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The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2015 | Research article

Contact heat evoked potentials and habituation measured interictally in migraineurs

Authors: Lena Clara Beese, Denise Putzer, Nani Osada, Stefan Evers, Martin Marziniak

Published in: The Journal of Headache and Pain | Issue 1/2015

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Abstract

Background

A lack of habituation of different evoked potential modalities in migraine patients in-between attacks has been suggested.

Methods

This study investigates cortical response after painful stimuli evaluated by contact heat evoked potentials (CHEPs) and quantitative sensory testing (QST) during the migraine-free interval. We enrolled 22 migraine patients and 22 healthy subjects.

Results

Cortical potentials after contact heat stimulation of the cheeks and the volar forearm at a temperature of 51°C showed significantly reduced A-δ-amplitudes in patients and healthy controls. When the subjects’ attention was drawn to an arithmetic task, a partial lack of habituation of amplitude could be seen in migraine patients. QST did not show any difference between migraineurs and controls.

Conclusion

Our findings can be primarily deemed to demonstrate that patients and healthy controls show significantly lower amplitudes while performing the calculation task. Without performing the calculation task we could not show the expected lack of habituation in migraineurs. Yet, while performing the calculation task our results partly suggest that hypothesis.
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Metadata
Title
Contact heat evoked potentials and habituation measured interictally in migraineurs
Authors
Lena Clara Beese
Denise Putzer
Nani Osada
Stefan Evers
Martin Marziniak
Publication date
01-12-2015
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-16-1

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