Published in:
Open Access
01-12-2014 | Meeting abstract
EHMTI-0360. Chronic sympathetic activation in migraine headache: unique to migraine or common to sympathetic nervous system disorders?
Author:
MR Thomas
Published in:
The Journal of Headache and Pain
|
Special Issue 1/2014
Login to get access
Excerpt
The mechanisms of autonomic nervous system dysfunction in migraine are not well understood. It has been proposed that chronic/excessive SNS activation contributes to migraine episodes by rapidly depleting norepinephrine stores while increasing the release of dopamine, adenosine triphosphate, adenosine and prostaglandins. Research showing significantly colder hands in female migraineurs than healthy controls between headaches suggests evidence of chronic/excessive SNS activation in female migraineurs. …