Published in:
Open Access
01-12-2014 | Meeting abstract
EHMTI-0336. Metabolic diet therapy in the prophylactic treatment of migraine headache in adolescents by using ketogenic diet
Authors:
MK Farkas, E Mak, E Richter, V Farkas
Published in:
The Journal of Headache and Pain
|
Special Issue 1/2014
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Excerpt
The high-fat, low-carbohydrate KD is a well-known add-on treatment option for children with medically intractable epilepsy. Anticonvulsants as topiramate can be helpful for migraine prophylaxis in chilndren, however, there are severe cautions by using chronic drug treatment by the parents. Several mechanics may exist for the effect of KD in CNS diseases: including disruption of glutamatergic synaptic transmission, inhibition of glycosis, activation of ATP-sensitive potassium channels and alteration of the mTOR pathway by modifying the brain excitability. …