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Published in: The Journal of Headache and Pain 1/2014

Open Access 01-12-2014 | Meeting abstract

EHMTI-0287. Peptides involved in sleep and appetite homeostatic regulation and its effects in the modulation of trigeminovascular nociceptive activation

Authors: M Martins Oliveira, S Akerman, J Hoffmann, P Goadsby

Published in: The Journal of Headache and Pain | Special Issue 1/2014

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Excerpt

Disturbances in appetite and sleep contribute to triggering in migraineurs. Neuropeptide Y (NPY), leptin and insulin are involved in hypothalamic appetite and sleep regulation, and pain modulation. The orexinergic system, known to modulate trigeminocervical complex (TCC) nociceptive activation, is reciprocally influenced by NPY, leptin and insulin. Importantly, hypothalamic activation is involved in migraine pathophysiology. …
Metadata
Title
EHMTI-0287. Peptides involved in sleep and appetite homeostatic regulation and its effects in the modulation of trigeminovascular nociceptive activation
Authors
M Martins Oliveira
S Akerman
J Hoffmann
P Goadsby
Publication date
01-12-2014
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue Special Issue 1/2014
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-15-S1-F18

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