Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
The Journal of Headache and Pain
Published in: The Journal of Headache and Pain 1/2013

Open Access 01-12-2013 | Research article

Elevated blood pressure and analgesic overuse in chronic daily headache: an outpatient clinic-based study from China

Authors: Qingqing Huang, Wangwen Li, Nan Li, Jing Wang, Ge Tan, Lixue Chen, Guangcheng Qin, Xiping Liang, Jiying Zhou

Published in: The Journal of Headache and Pain | Issue 1/2013

Login to get access

Abstract

Background

Many studies have reported that hypertension is common in chronic daily headache (CDH) and its subtype chronic migraine (CM), but the reason is still poorly understood. Our clinical literature review suggested that analgesic overuse may be associated with elevated blood pressure (BP), so we performed the present study to investigate the frequency of elevated BP and its link with analgesic overuse in CDH and its subtypes.

Methods

A cross-sectional study was conducted in neurology outpatients with a diagnosis of CDH according to International Headache Society criteria. CDH patients were classified into CM and non-CM groups, and subclassified with or without analgesic overuse.

Results

Elevated BP was present in 27.96% of CDH patients. Compared with non-CM patients, patients with CM had a longer duration of headache and more severe pain intensity, and a family history of headache and analgesic overuse were also more common, but the elevated BP frequency was not different between the two groups. Almost one-third of the patients had analgesic overuse; 96.8% of which comprised acetaminophen-containing agents. Those with analgesic overuse had a higher frequency of headache than those without analgesic overuse in both the CM and non-CM groups.

Conclusions

Although the CM patients had a longer duration of headache, more severe intensity, the frequency of elevated BP wasn’t higher than non-CM group. Analgesic overuses maybe the reason of higher frequency of elevated BP in CDH and its subtypes. This may have predictive value for clinicians to improve CDH management.
Literature
1.
Stovner L, Hagen K, Jensen R, Katsarava Z, Lipton R, Scher A, Steiner T, Zwart JA: The global burden of headache:a documentation of headache prevalence and disability worldwide. Cephalalgia 2007,27(3):193–210. 10.1111/j.1468-2982.2007.01288.xPubMedCrossRef
2.
Lantéri-Minet M, Auray JP, El Hasnaoui A, Dartigues JF, Duru G, Henry P, Lucas C, Pradalier A, Chazot G, Gaudin AF: Prevalence and description of chronic daily headache in the general population of France. Pain 2003,102(1–2):143–149.PubMedCrossRef
3.
Gipponi S, Venturelli E, Rao R, Liberini P, Padovani A: Hypertension is a factor associated with chronic daily headache. Neurol Sci 2010,31(S1):171–173. 10.1007/s10072-010-0322-5CrossRef
4.
Buse DC, Manack A, Serrano D, Turkel C, Lipton RB: Sociodemographic and comorbidity profiles of chronic migraine and episodic migraine sufferers. J Neurol Neurosur PS 2010,81(4):428–432. 10.1136/jnnp.2009.192492CrossRef
5.
Bigal ME, Sheftell FD, Rapoport AM, Tepper SJ, Lipton RB: Chronic Daily Headache: Identification of Factors Associated With Induction and Transformation. Headache 2002,42(7):575–581. 10.1046/j.1526-4610.2002.02143.xPubMedCrossRef
6.
Rosanna C, Maria Pia P, Piero B, Mariantonietta S, Virgilio G, Andrea A, Maria N, Stefania C, Gennaro B, Domenico D’A, Giuseppe L, Licia G, Franco G, Giorgio Z, Giorgio S, Anna Pia V, Giorgio N, Giuliano R: The importance of anxiety and depression as factors in chronicization of primary headaches. J Headache Pain 2000,1(suppl):S45-S48.
7.
Silberstein SD, Lipton RB, Sliwinski M: Classification of daily and near-daily headaches: field trial of revised IHS criteria. Neurology 1996,47(4):871–875. 10.1212/WNL.47.4.871PubMedCrossRef
8.
Manzoni GC, Granella F, Sandrini G, Cavallini A, Zanferrari C, Nappi G: Classification of chronic daily headache by International Headache Society criteria: limits and new proposals. Cephalalgia 1995,15(1):37–43. 10.1046/j.1468-2982.1995.1501037.xPubMedCrossRef
9.
Rothrock J, Patel M, Lyden P, Jackson C: Demographic and clinical characteristics of patients with episodic migraine versus chronic daily headache. Cephalalgia 1996,16(1):44–49. 10.1046/j.1468-2982.1996.1601044.xPubMedCrossRef
10.
Mathew NT, Stubits E, Nigam MP: Transformation of episodic migraine into daily headache: analysis of factors. Headache 1982,22(2):66–68. 10.1111/j.1526-4610.1982.hed2202066.xPubMedCrossRef
11.
Wang SJ, Fuh JL, Lu SR, Liu CY, Hsu LC, Wang PN, Liu HC: Chronic daily headache in Chinese elderly Prevalence, risk factors, and biannual follow-up. Neurology 2000,54(2):314–319. 10.1212/WNL.54.2.314PubMedCrossRef
12.
Yunfeng W, Jiying Z, Xiaoping F, Xuelian L, Li R, Ge T, Lixue C, Kuiyun W, Bowen L: Classification and clinical features of headache patients: an outpatient clinic study from China. J Headache Pain 2011,12(5):561–567. 10.1007/s10194-011-0360-2CrossRef
13.
14.
Forman JP, Rimm EB, Curhan GC: Frequency of analgesic use and risk of hypertension among men. Arch Intern Med 2007, 167: 394–399. 10.1001/archinte.167.4.394PubMedCrossRef
15.
Sudano I, Flammer AJ, Périat D, Enseleit F, Hermann M, Wolfrum M, Hirt A, Kaiser P, Hurlimann D, Neidhart M, Gay S, Holzmeister J, Nussberger J, Mocharla P, Landmesser U, Haile SR, Corti R, Vanhoutte PM, Lüscher TF, Noll G, Ruschitzka F: Acetaminophen Increases Blood Pressure in Patients With Coronary Artery Disease. Circulation 2010,122(18):1789–1796. 10.1161/CIRCULATIONAHA.110.956490PubMedCrossRef
16.
Forman JP, Stampfer MJ, Curhan GC: Non-Narcotic Analgesic Dose and Risk of Incident Hypertension in US Women. Hypertension 2005,46(3):500–507. 33 10.1161/01.HYP.0000177437.07240.70PubMedCrossRef
17.
Curhan GC, Willett WC, Rosner B, Stampfer MJ: Frequency of analgesic use and risk of hypertension in younger women. Arch Intern Med 2002,162(19):2204–2208. 35 10.1001/archinte.162.19.2204PubMedCrossRef
18.
Hennekens CH: Aspirin fcin the treatment and prevention of cardiovascular disease: current perspective and future directions. Curr Atheroscler Rep 2007,9(5):409–416. 16 10.1007/s11883-007-0053-0PubMedCrossRef
19.
Baigent C, Blackwell L, Collins R, Emberson J, Godwin J, Peto R, Buring J, Hennekens C, Kearney P, Meade T, Patrono C, Roncaglioni MC, Zanchetti A, Antithrombotic Trialists' (ATT) Collaboration: Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomized trials. Lancet 2009,373(9678):1849–1860. 17PubMedCrossRef
20.
Silberstein SD, Lipton RB: Chronic daily headache, including transformed migraine, chronic tension-type headache, and medication overuse. Wolff’s headache and other head pain 2001, 7: 247–282. 18
21.
Silberstein Stephen D, Lipton Richard B: Chronic daily headache. Curr Opin Neurol 2000,13(3):277–283. 19 10.1097/00019052-200006000-00008CrossRef
22.
Bigal ME, Lipton RB: The differential diagnosis of chronic daily headaches: an algorithm-based approach. J Headache Pain 2007,8(5):263–272. 20 10.1007/s10194-007-0418-3PubMedCentralPubMedCrossRef
23.
Li X, Zhou J, Tan G, Wang Y, Ran L, Chen L: Clinical characteristics of tension-type headache in the neurological clinic of a university hospital in China. Neurol Sci 2012,33(2):283–287. 21 10.1007/s10072-011-0675-4PubMedCrossRef
24.
Wang J, Huang Q, Li N, Tan G, Chen L, Zhou J: Triggers of migraine and tension-type headache in China: a clinic-based survey. Eur J Neurol 2013,20(4):689–696. 22 10.1111/ene.12039PubMedCrossRef
25.
Nan L, Jing W, Qingqing H, Ge T, Lixue C, Jiying Z: Clinical features of new daily persistent headache in a tertiary outpatient population. Headache 2012,52(10):1546–1552. 10.1111/j.1526-4610.2012.02278.xCrossRef
26.
Pietrini U, De Luca M, De Santis G: Hypertension in headache patients? A clinical study. Acta Neurol Scand 2005,112(4):259–264. 10.1111/j.1600-0404.2005.00476.xPubMedCrossRef
27.
Mancia G, Rosei EA, Ambrosioni E, Avino F, Carolei A, Daccò M, Di Giacomo G, Ferri C, Grazioli I, Melzi G, Nappi G, Pinessi L, Sandrini G, Trimarco B, Zanchin G, MIRACLES Study Group: Hypertension and migraine comorbidity: prevalence and risk of cerebrovascular events: evidence from a large, multicenter, cross-sectional survey in Italy (MIRACLES study). J Hypertens 2011,29(2):309–318. 10.1097/HJH.0b013e3283410404PubMedCrossRef
28.
Gus M, Fuchs FD, Pimentel M, Rosa D, Melo AG, Moreira LB: Behavior of Ambulatory Blood Pressure Surrounding Episodes of Headache in Mildly Hypertensive Patients. Arch Intern Med 2001,161(2):252–255. 10.1001/archinte.161.2.252PubMedCrossRef
29.
WATERS WE: Headache and blood pressure in the community. BMJ 1971,5741(1):142–143.CrossRef
30.
Cooper WD, Glover DR, Hormbrey JM, Kimber GR: Headache and blood pressure: evidence of a close relationship. J Hum Hypertension 1989,3(1):41–44.
31.
Onder G, Pahor M, Gambassi G, Federici A, Savo A, Carbonin P, Bernabei R: Association between ACE inhibitors use and headache caused by nitrates among hypertensive patients: results from the Italian group of pharmacoepidemiology in the elderly (GIFA). Cephalalgia 2003,23(9):901–906. 10.1046/j.1468-2982.2003.00627.xPubMedCrossRef
32.
Ziegler DK, Hassanein RS, Couch JR: Characteristics of life headache histories in a nonclinic population. Neurology 1977,27(3):265–269. 10.1212/WNL.27.3.265PubMedCrossRef
33.
2010 Chinese guidelines for the management of hypertension. Writing Group of 2010 Chinese Guidelines for the Management of Hypertension Zhonghua Xin Xue Guan Bing Za Zhi 2011,39(7):579–615.
34.
Dedier J, Stampfer MJ, Hankinson SE, Willett WC, Speizer FE, Curhan GC: Nonnarcotic analgesic use and the risk of hypertension in US women. Hypertension 2002,40(5):604–608. 34 10.1161/01.HYP.0000035856.77718.DAPubMedCrossRef
35.
Pope JE, Anderson JJ, Felson DT: A meta-analysis of the effects of nonsteroidal anti-inflammatory drugs on blood pressure. Arch Intern Med 1993,153(4):477–484. 10.1001/archinte.1993.00410040045007PubMedCrossRef
36.
37.
Imai N, Kitamura E, Konishi T, Suzuki Y, Serizawa M, Okabe T: Clinical features of probable medication-overuse headache: a retrospective study in Japan. Cephalalgia 2007,27(9):1020–1023. 10.1111/j.1468-2982.2007.01389.xPubMedCrossRef
38.
Limmroth V, Katsarava Z, Fritsche G, Przywara S, Diener HC: Features of medication overuse headache following overuse of different acute headache drugs. Neurology 2002,59(7):1011–1014. 10.1212/WNL.59.7.1011PubMedCrossRef
39.
Winter AC, Klaus B, Buring JE, Tobias K: Associations of socioeconomic status with migraine and non-migraine headache. Cephalalgia 2012,32(2):159–170. 10.1177/0333102411430854PubMedCentralPubMedCrossRef
40.
Pernilla J, Mattias L, Gunnel H, Tove H: Sociodemographic differences in medication use, health-care contacts and sickness absence among individuals with medication-overuse headache. J Headache Pain 2012,13(4):281–290. 10.1007/s10194-012-0432-yCrossRef
41.
Jonsson P, Hedenrud T, Linde M: Epidemiology of medication overuse headache in the general Swedish population. Cephalalgia 2011,31(9):1015–1022. 10.1177/0333102411410082PubMedCrossRef
42.
Atasoy HT, Unal AE, Atasoy N, Emre U, Sumer M: Low income and education levels may cause medication overuse and chronicity in migraine patients. Headache 2005,45(1):25–31. 10.1111/j.1526-4610.2005.05006.xPubMedCrossRef
43.
Barbanti P, Aurilia C, Egeo G, Fofi L: Hypertension as a risk factor for migraine chronification. Neurol Sci 2010,31(S1):41–43. 10.1007/s10072-010-0269-6CrossRef
44.
Lennart Hansson MDHGS, Richard R, Pablo L: Headache in Mild-to-Moderate Hypertension and Its Reduction by Irbesartan Therapy. Arch Intern Med 2000, 160: 1654–1658. 10.1001/archinte.160.11.1654CrossRef
Metadata
Title
Elevated blood pressure and analgesic overuse in chronic daily headache: an outpatient clinic-based study from China
Authors
Qingqing Huang
Wangwen Li
Nan Li
Jing Wang
Ge Tan
Lixue Chen
Guangcheng Qin
Xiping Liang
Jiying Zhou
Publication date
01-12-2013
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 1/2013
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/1129-2377-14-51

Other articles of this Issue 1/2013

The Journal of Headache and Pain 1/2013 Go to the issue

Review article

Diagnostic and therapeutic errors in trigeminal autonomic cephalalgias and hemicrania continua: a systematic review

Research article

Period prevalence of self-reported headache in the general population in Germany from 1995–2005 and 2009: results from annual nationwide population-based cross-sectional surveys

Research article

Probable medications overuse headaches: validation of a brief easy-to-use screening tool in a headache centre

Research article

Primary headaches, attention deficit disorder and learning disabilities in children and adolescents

Short report

Self-reported efficacy of complementary and alternative medicine: the Akershus study of chronic headache

Book review

Pain comorbidities – understanding and treating the complex patient: IASP Press, 2012