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Open Access 01-12-2021 | Multiple Sclerosis | Letter to the editor

N,N-Dimethylglycine in patients with progressive multiple sclerosis: result of a pilot double-blind, placebo, controlled randomized clinical trial

Authors: Thomas Wolfsegger, Klaus Böck, Wolfgang Schimetta, Tim J. von Oertzen, Hamid Assar

Published in: Neurological Research and Practice | Issue 1/2021

Abstract

Oral administration of N,N-Dimethylglycine (DMG), a tertiary amino acid, presumably enhances oxygen utilization by tissue and complex with free radicals. Beneficial effects are improved endurance performance and reduction fatigue in humans and animals. This pilot study reports the results over a one-year double-blind, placebo-controlled trial of DMG in 30 randomized patients with progressive multiple sclerosis. No treatment effects were found between the placebo group and the DMG group for disability, fatigue, cognitive, or gait parameters.

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Title: N,N-Dimethylglycine in patients with progressive multiple sclerosis: result of a pilot double-blind, placebo, controlled randomized clinical trial
Authors: Thomas Wolfsegger
Klaus Böck
Wolfgang Schimetta
Tim J. von Oertzen
Hamid Assar
Publication date: 01-12-2021
Publisher: BioMed Central
Keywords: Multiple Sclerosis
Nutrition
Fatigue
Published in: Neurological Research and Practice / Issue 1/2021
Electronic ISSN: 2524-3489
DOI: https://doi.org/10.1186/s42466-021-00126-z

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N,N-Dimethylglycine in patients with progressive multiple sclerosis: result of a pilot double-blind, placebo, controlled randomized clinical trial

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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