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JA Clinical Reports

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Open Access 01-12-2017 | Clinical research letter

Low preoperative regional cerebral oxygen saturation in hemodialysis patients

Authors: Shino Matsukawa, Miho Hamada, Toshiyuki Mizota

Published in: JA Clinical Reports | Issue 1/2017

Abstract

Background

Regional cerebral oxygen saturation (rSO₂) monitoring by near-infrared spectroscopy provides valuable information regarding cerebral oxygen delivery, and it has been increasingly used in cardiovascular surgery. Although it has been shown that dialysis-dependent patients [hemodialysis (HD) patients] suffer from low cerebral perfusion, limited information is available on cerebral tissue oxygenation levels in HD patients.

Findings

In this retrospective study, the preoperative rSO₂ values in 9 HD patients undergoing coronary artery bypass graft surgery were compared with those in 40 non-HD patients. HD patients had lower preoperative rSO₂ values than non-HD patients (median: 46 vs. 68%, respectively, P < 0.001). Despite adjusting for age, hemoglobin concentration, and left ventricular ejection fraction using multivariable linear regression, HD showed a strong association with low rSO₂ (estimated coefficient: −20.4, P < 0.001).

Conclusions

HD showed a strong association with low preoperative rSO₂ values in patients undergoing coronary artery bypass graft surgery, even after adjusting for known factors that affect rSO₂ values, including age, hemoglobin concentration, and cardiac systolic function. Further research is required to elucidate the mechanisms decreasing rSO₂ values in HD patients.

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Title: Low preoperative regional cerebral oxygen saturation in hemodialysis patients
Authors: Shino Matsukawa
Miho Hamada
Toshiyuki Mizota
Publication date: 01-12-2017
Publisher: Springer Berlin Heidelberg
Published in: JA Clinical Reports / Issue 1/2017
Electronic ISSN: 2363-9024
DOI: https://doi.org/10.1186/s40981-017-0084-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Low preoperative regional cerebral oxygen saturation in hemodialysis patients

Abstract

Background

Findings

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Findings

Conclusions

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