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Maxillofacial Plastic and Reconstructive Surgery

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Open Access 01-12-2015 | Research

Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study

Authors: Si-Yeok Park, Young-Wook Park, Young-Jun Ji, Sung-Wook Park, Seong-Gon Kim

Published in: Maxillofacial Plastic and Reconstructive Surgery | Issue 1/2015

Abstract

Background

The aim of this study was to investigate the effect of a botulinum toxin type A (BTX-A) injection in the masseter muscle using electromyography (EMG) in an animal model.

Methods

Ten male adult (>3 months of age) New Zealand white rabbits were used. Muscle activity was continuously recorded from 8 hours before to 8 hours after BTX-A injection. The rabbits received unilateral BTX-A injections of either 5 units (group 1, n = 5) or 20 units (group 2, n = 5).

Results

The masseter muscle activity of the rabbits was significantly reduced immediately after BTX-A injection (P < 0.05 for both groups). When the results from group 1 were compared with those from group 2, only the peak voltage was significantly decreased in group 2 (P = 0.013).

Conclusion

Masseter muscle activity measured by EMG was immediately decreased after a BTX-A injection.

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Title: Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study
Authors: Si-Yeok Park
Young-Wook Park
Young-Jun Ji
Sung-Wook Park
Seong-Gon Kim
Publication date: 01-12-2015
Publisher: Springer Berlin Heidelberg
Published in: Maxillofacial Plastic and Reconstructive Surgery / Issue 1/2015
Electronic ISSN: 2288-8586
DOI: https://doi.org/10.1186/s40902-015-0010-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effects of a botulinum toxin type A injection on the masseter muscle: An animal model study

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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