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Published in: BMC Nutrition 1/2016

Open Access 01-12-2016 | Correspondence

Low mid-upper arm circumference identifies children with a high risk of death who should be the priority target for treatment

Authors: André Briend, José-Luis Alvarez, Nathalie Avril, Paluku Bahwere, Jeanette Bailey, James A. Berkley, Paul Binns, Nikki Blackwell, Nancy Dale, Hedwig Deconinck, Pascale Delchevalerie, Nicky Dent, Maureen Gallagher, Saul Guerrero, Kerstin Hanson, Marko Kerac, Mark Manary, Martha K. Mwangome, Mark Myatt, Kevin P. Q. Phelan, Silke Pietzsch, Núria Salse Ubach, Susan Shepherd, Saskia van der Kam, Antonio Vargas, Sophie Whitney

Published in: BMC Nutrition | Issue 1/2016

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Abstract

Background

Severe acute malnutrition (SAM) is currently defined by the WHO as either a low mid-upper arm circumference (i.e. MUAC <115 mm), a low weight-for-height z-score (i.e. WHZ <− 3), or bilateral pitting oedema. MUAC and WHZ do not always identify the same children as having SAM. This has generated broad debate, as illustrated by the recent article by Grellety & Golden (BMC Nutr. 2016;2:10).

Discussion

Regional variations in the proportion of children selected by each index seem mostly related to differences in body shape, including stuntedness. However, the practical implications of these variations in relation to nutritional status and also to outcome are not clear. All studies that have examined the relationship between anthropometry and mortality in representative population samples in Africa and in Asia have consistently showed that MUAC is more sensitive at high specificity levels than WHZ for identifying children at high risk of death. Children identified as SAM cases by low MUAC gain both weight and MUAC in response to treatment. The widespread use of MUAC has brought enormous benefits in terms of the coverage and efficiency of programs. As a large high-risk group responding to treatment, children with low MUAC should be regarded as a public health priority independently of their WHZ.

Conclusion

While a better understanding of the mechanism behind the discrepancy between MUAC and WHZ is desirable, research in this area should not delay the implementation of programs aiming at effectively reducing malnutrition-related deaths by prioritising the detection and treatment of children with low MUAC.
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Metadata
Title
Low mid-upper arm circumference identifies children with a high risk of death who should be the priority target for treatment
Authors
André Briend
José-Luis Alvarez
Nathalie Avril
Paluku Bahwere
Jeanette Bailey
James A. Berkley
Paul Binns
Nikki Blackwell
Nancy Dale
Hedwig Deconinck
Pascale Delchevalerie
Nicky Dent
Maureen Gallagher
Saul Guerrero
Kerstin Hanson
Marko Kerac
Mark Manary
Martha K. Mwangome
Mark Myatt
Kevin P. Q. Phelan
Silke Pietzsch
Núria Salse Ubach
Susan Shepherd
Saskia van der Kam
Antonio Vargas
Sophie Whitney
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Nutrition / Issue 1/2016
Electronic ISSN: 2055-0928
DOI
https://doi.org/10.1186/s40795-016-0101-7

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