Skip to main content
Top
Published in: Clinical and Translational Allergy 1/2016

Open Access 01-12-2016 | Editorial

Hypothesis: may e-cigarette smoking boost the allergic epidemic?

Authors: Jean Bousquet, Claus Bachert, Laura Crotty Alexander, Frank T. Leone

Published in: Clinical and Translational Allergy | Issue 1/2016

Login to get access

Excerpt

IgE-associated allergic diseases represent a global health problem increasing in prevalence and severity. An epidemic of IgE-associated allergic diseases has occurred over the past decades globally [1, 2] and many factors driving this epidemic are not clear. The most common diseases (asthma, rhinitis and eczema) are linked, at least partly, to IgE immune response. These diseases are complex multifactorial disorders, with both genetic and environmental components. Reasons explaining the allergy epidemic are not clear. Many inhalants such as air pollution and diesel exhaust particulates are associated with a modulation of the IgE response [3]. On the other hand, tobacco smoking has a minimal effect on the increased prevalence or severity of allergic rhinitis [4]. …
Literature
1.
go back to reference Bousquet J, Anto J, Auffray C, Akdis M, Cambon-Thomsen A, Keil T, et al. MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine. Allergy. 2011;66(5):596–604.CrossRefPubMed Bousquet J, Anto J, Auffray C, Akdis M, Cambon-Thomsen A, Keil T, et al. MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine. Allergy. 2011;66(5):596–604.CrossRefPubMed
3.
go back to reference Behrendt H, Alessandrini F, Buters J, Kramer U, Koren H, Ring J. Environmental pollution and allergy: historical aspects. Chem Immunol Allergy. 2014;100:268–77.CrossRefPubMed Behrendt H, Alessandrini F, Buters J, Kramer U, Koren H, Ring J. Environmental pollution and allergy: historical aspects. Chem Immunol Allergy. 2014;100:268–77.CrossRefPubMed
4.
go back to reference Saulyte J, Regueira C, Montes-Martinez A, Khudyakov P, Takkouche B. Active or passive exposure to tobacco smoking and allergic rhinitis, allergic dermatitis, and food allergy in adults and children: a systematic review and meta-analysis. PLoS Med. 2014;11(3):e1001611.CrossRefPubMedPubMedCentral Saulyte J, Regueira C, Montes-Martinez A, Khudyakov P, Takkouche B. Active or passive exposure to tobacco smoking and allergic rhinitis, allergic dermatitis, and food allergy in adults and children: a systematic review and meta-analysis. PLoS Med. 2014;11(3):e1001611.CrossRefPubMedPubMedCentral
5.
go back to reference Dingel MJ, Karkazis K, Koenig BA. Framing nicotine addiction as a “disease of the brain”: social and ethical consequences. Soc Sci Q. 2012;92(5):1363–88.PubMed Dingel MJ, Karkazis K, Koenig BA. Framing nicotine addiction as a “disease of the brain”: social and ethical consequences. Soc Sci Q. 2012;92(5):1363–88.PubMed
7.
go back to reference Leone FT, Evers-Casey S. Developing a rational approach to tobacco use treatment in pulmonary practice: a review of the biological basis of nicotine addiction. Clin Pulm Med. 2012;19(2):53–61.CrossRefPubMedPubMedCentral Leone FT, Evers-Casey S. Developing a rational approach to tobacco use treatment in pulmonary practice: a review of the biological basis of nicotine addiction. Clin Pulm Med. 2012;19(2):53–61.CrossRefPubMedPubMedCentral
9.
go back to reference Drummond MB, Upson D. Electronic cigarettes. Potential harms and benefits. Ann Am Thorac Soc. 2014;11(2):236–42.CrossRefPubMed Drummond MB, Upson D. Electronic cigarettes. Potential harms and benefits. Ann Am Thorac Soc. 2014;11(2):236–42.CrossRefPubMed
10.
go back to reference Li J, Bullen C, Newcombe R, Walker N, Walton D. The use and acceptability of electronic cigarettes among New Zealand smokers. N Z Med J. 2013;126(1375):48–57.PubMed Li J, Bullen C, Newcombe R, Walker N, Walton D. The use and acceptability of electronic cigarettes among New Zealand smokers. N Z Med J. 2013;126(1375):48–57.PubMed
11.
go back to reference Kandra KL, Ranney LM, Lee JG, Goldstein AO. Physicians’ attitudes and use of e-cigarettes as cessation devices, North Carolina, 2013. PLoS ONE. 2014;9(7):e103462.CrossRefPubMedPubMedCentral Kandra KL, Ranney LM, Lee JG, Goldstein AO. Physicians’ attitudes and use of e-cigarettes as cessation devices, North Carolina, 2013. PLoS ONE. 2014;9(7):e103462.CrossRefPubMedPubMedCentral
12.
go back to reference Nutt DJ, Phillips LD, Balfour D, Curran HV, Dockrell M, Foulds J, et al. Estimating the harms of nicotine-containing products using the MCDA approach. Eur Addict Res. 2014;20(5):218–25.CrossRefPubMed Nutt DJ, Phillips LD, Balfour D, Curran HV, Dockrell M, Foulds J, et al. Estimating the harms of nicotine-containing products using the MCDA approach. Eur Addict Res. 2014;20(5):218–25.CrossRefPubMed
13.
go back to reference Goniewicz ML, Lingas EO, Hajek P. Patterns of electronic cigarette use and user beliefs about their safety and benefits: an internet survey. Drug Alcohol Rev. 2013;32(2):133–40.CrossRefPubMed Goniewicz ML, Lingas EO, Hajek P. Patterns of electronic cigarette use and user beliefs about their safety and benefits: an internet survey. Drug Alcohol Rev. 2013;32(2):133–40.CrossRefPubMed
14.
go back to reference Sleiman M, Logue JM, Montesinos VN, Russell ML, Litter MI, Gundel LA, et al. Emissions from electronic cigarettes: key parameters affecting the release of harmful chemicals. Environ Sci Technol. 2016;50(17):9644–51.CrossRefPubMed Sleiman M, Logue JM, Montesinos VN, Russell ML, Litter MI, Gundel LA, et al. Emissions from electronic cigarettes: key parameters affecting the release of harmful chemicals. Environ Sci Technol. 2016;50(17):9644–51.CrossRefPubMed
15.
go back to reference Kosmider L, Sobczak A, Fik M, Knysak J, Zaciera M, Kurek J, et al. Carbonyl compounds in electronic cigarette vapors: effects of nicotine solvent and battery output voltage. Nicot Tob Res. 2014;16(10):1319–26.CrossRef Kosmider L, Sobczak A, Fik M, Knysak J, Zaciera M, Kurek J, et al. Carbonyl compounds in electronic cigarette vapors: effects of nicotine solvent and battery output voltage. Nicot Tob Res. 2014;16(10):1319–26.CrossRef
16.
go back to reference Rowell TR, Tarran R. Will chronic e-cigarette use cause lung disease? Am J Physiol Lung Cell Mol Physiol. 2015;309(12):L1398–409.CrossRefPubMed Rowell TR, Tarran R. Will chronic e-cigarette use cause lung disease? Am J Physiol Lung Cell Mol Physiol. 2015;309(12):L1398–409.CrossRefPubMed
17.
go back to reference Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, et al. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016;94(6):667–79.CrossRef Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, et al. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016;94(6):667–79.CrossRef
18.
19.
go back to reference Sussan TE, Gajghate S, Thimmulappa RK, Ma J, Kim JH, Sudini K, et al. Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model. PLoS ONE. 2015;10(2):e0116861.CrossRefPubMedPubMedCentral Sussan TE, Gajghate S, Thimmulappa RK, Ma J, Kim JH, Sudini K, et al. Exposure to electronic cigarettes impairs pulmonary anti-bacterial and anti-viral defenses in a mouse model. PLoS ONE. 2015;10(2):e0116861.CrossRefPubMedPubMedCentral
20.
go back to reference Lim HB, Kim SH. Inhallation of e-cigarette cartridge solution aggravates allergen-induced airway inflammation and hyper-responsiveness in mice. Toxicol Res. 2014;30(1):13–8.CrossRefPubMedPubMedCentral Lim HB, Kim SH. Inhallation of e-cigarette cartridge solution aggravates allergen-induced airway inflammation and hyper-responsiveness in mice. Toxicol Res. 2014;30(1):13–8.CrossRefPubMedPubMedCentral
21.
go back to reference Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, et al. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016;94(6):667–79.CrossRefPubMed Hwang JH, Lyes M, Sladewski K, Enany S, McEachern E, Mathew DP, et al. Electronic cigarette inhalation alters innate immunity and airway cytokines while increasing the virulence of colonizing bacteria. J Mol Med (Berl). 2016;94(6):667–79.CrossRefPubMed
22.
go back to reference Wu Q, Jiang D, Minor M, Chu HW. Electronic cigarette liquid increases inflammation and virus infection in primary human airway epithelial cells. PLoS ONE. 2014;9(9):e108342.CrossRefPubMedPubMedCentral Wu Q, Jiang D, Minor M, Chu HW. Electronic cigarette liquid increases inflammation and virus infection in primary human airway epithelial cells. PLoS ONE. 2014;9(9):e108342.CrossRefPubMedPubMedCentral
23.
go back to reference Vardavas CI, Anagnostopoulos N, Kougias M, Evangelopoulou V, Connolly GN, Behrakis PK. Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide. Chest. 2012;141(6):1400–6.CrossRefPubMed Vardavas CI, Anagnostopoulos N, Kougias M, Evangelopoulou V, Connolly GN, Behrakis PK. Short-term pulmonary effects of using an electronic cigarette: impact on respiratory flow resistance, impedance, and exhaled nitric oxide. Chest. 2012;141(6):1400–6.CrossRefPubMed
24.
go back to reference Bachert C, Zhang N. Chronic rhinosinusitis and asthma: novel understanding of the role of IgE ‘above atopy’. J Intern Med. 2012;272(2):133–43.CrossRefPubMed Bachert C, Zhang N. Chronic rhinosinusitis and asthma: novel understanding of the role of IgE ‘above atopy’. J Intern Med. 2012;272(2):133–43.CrossRefPubMed
25.
go back to reference Stentzel S, Teufelberger A, Nordengrun M, Kolata J, Schmidt F, van Crombruggen K, et al. Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus. J Allergy Clin Immunol. 2016. doi:10.1016/j.jaci.2016.03.045.PubMed Stentzel S, Teufelberger A, Nordengrun M, Kolata J, Schmidt F, van Crombruggen K, et al. Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus. J Allergy Clin Immunol. 2016. doi:10.​1016/​j.​jaci.​2016.​03.​045.PubMed
26.
go back to reference Tomassen P, Jarvis D, Newson R, Van Ree R, Forsberg B, Howarth P, et al. Staphylococcus aureus enterotoxin-specific IgE is associated with asthma in the general population: a GA(2)LEN study. Allergy. 2013;68(10):1289–97.CrossRefPubMed Tomassen P, Jarvis D, Newson R, Van Ree R, Forsberg B, Howarth P, et al. Staphylococcus aureus enterotoxin-specific IgE is associated with asthma in the general population: a GA(2)LEN study. Allergy. 2013;68(10):1289–97.CrossRefPubMed
27.
go back to reference Bachert C, van Steen K, Zhang N, Holtappels G, Cattaert T, Maus B, et al. Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma. J Allergy Clin Immunol. 2012;130(2):376–81.CrossRefPubMed Bachert C, van Steen K, Zhang N, Holtappels G, Cattaert T, Maus B, et al. Specific IgE against Staphylococcus aureus enterotoxins: an independent risk factor for asthma. J Allergy Clin Immunol. 2012;130(2):376–81.CrossRefPubMed
28.
go back to reference Song WJ, Sintobin I, Sohn KH, Kang MG, Park HK, Jo EJ, et al. Staphylococcal enterotoxin IgE sensitization in late-onset severe eosinophilic asthma in the elderly. Clin Exp Allergy. 2016;46(3):411–21.CrossRefPubMed Song WJ, Sintobin I, Sohn KH, Kang MG, Park HK, Jo EJ, et al. Staphylococcal enterotoxin IgE sensitization in late-onset severe eosinophilic asthma in the elderly. Clin Exp Allergy. 2016;46(3):411–21.CrossRefPubMed
29.
go back to reference Bousquet J, Anto JM, Wickman M, Keil T, Valenta R, Haahtela T, et al. Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis. Allergy. 2015;70(9):1062–78.CrossRefPubMed Bousquet J, Anto JM, Wickman M, Keil T, Valenta R, Haahtela T, et al. Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis. Allergy. 2015;70(9):1062–78.CrossRefPubMed
30.
go back to reference Bousquet J, Anto JM, Akdis M, Auffray C, Keil T, Momas I, et al. Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story. Allergy 2016;71(11):1513–25.CrossRefPubMed Bousquet J, Anto JM, Akdis M, Auffray C, Keil T, Momas I, et al. Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story. Allergy 2016;71(11):1513–25.CrossRefPubMed
31.
go back to reference Abbasi J. FDA extends authority to e-cigarettes: implications for smoking cessation? JAMA 2016;316(6):572–4.CrossRefPubMed Abbasi J. FDA extends authority to e-cigarettes: implications for smoking cessation? JAMA 2016;316(6):572–4.CrossRefPubMed
32.
go back to reference Bousquet J, Knani J, Hejjaoui A, Ferrando R, Cour P, Dhivert H, et al. Heterogeneity of atopy. I. Clinical and immunologic characteristics of patients allergic to cypress pollen. Allergy. 1993;48(3):183–8.CrossRefPubMed Bousquet J, Knani J, Hejjaoui A, Ferrando R, Cour P, Dhivert H, et al. Heterogeneity of atopy. I. Clinical and immunologic characteristics of patients allergic to cypress pollen. Allergy. 1993;48(3):183–8.CrossRefPubMed
33.
go back to reference Polosa R, Campagna D, Sands MF. Counseling patients with asthma and allergy about electronic cigarettes: an evidence-based approach. Ann Allergy Asthma Immunol. 2016;116(2):106–11.CrossRefPubMed Polosa R, Campagna D, Sands MF. Counseling patients with asthma and allergy about electronic cigarettes: an evidence-based approach. Ann Allergy Asthma Immunol. 2016;116(2):106–11.CrossRefPubMed
Metadata
Title
Hypothesis: may e-cigarette smoking boost the allergic epidemic?
Authors
Jean Bousquet
Claus Bachert
Laura Crotty Alexander
Frank T. Leone
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Clinical and Translational Allergy / Issue 1/2016
Electronic ISSN: 2045-7022
DOI
https://doi.org/10.1186/s13601-016-0130-y

Other articles of this Issue 1/2016

Clinical and Translational Allergy 1/2016 Go to the issue