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Experimental & Translational Stroke Medicine

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Open Access 01-12-2016 | Review

Pathophysiology and management of reperfusion injury and hyperperfusion syndrome after carotid endarterectomy and carotid artery stenting

Authors: Muhammad U. Farooq, Christopher Goshgarian, Jiangyong Min, Philip B. Gorelick

Published in: Experimental & Translational Stroke Medicine | Issue 1/2016

Abstract

Cerebral hyperperfusion is a relatively rare syndrome with significant and potentially preventable clinical consequences. The pathophysiology of cerebral hyperperfusion syndrome (CHS) may involve dysregulation of the cerebral vascular system and hypertension, in the setting of increase in cerebral blood flow. The early recognition of CHS is important to prevent complications such as intracerebral hemorrhage. This review will focus on CHS following carotid endarterectomy and carotid artery stenting. We will discuss the typical clinical features of CHS, risk factors, pathophysiology, diagnostic modalities for detection, identification of patients at risk, and prevention and treatment. Although currently there are no specific guidelines for the management of CHS, identification of patients at risk for CHS and aggressive treatment of hypertension are recommended.

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Title: Pathophysiology and management of reperfusion injury and hyperperfusion syndrome after carotid endarterectomy and carotid artery stenting
Authors: Muhammad U. Farooq
Christopher Goshgarian
Jiangyong Min
Philip B. Gorelick
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: Experimental & Translational Stroke Medicine / Issue 1/2016
Electronic ISSN: 2040-7378
DOI: https://doi.org/10.1186/s13231-016-0021-2

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Springer Medicine

Pathophysiology and management of reperfusion injury and hyperperfusion syndrome after carotid endarterectomy and carotid artery stenting

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

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