Skip to main content
Top
Published in: Allergy, Asthma & Clinical Immunology 1/2017

Open Access 01-12-2017 | Letter to the editor

Allergic rhinitis: the eligible candidate to mite immunotherapy in the real world

Authors: Giorgio Ciprandi, Valentina Natoli, Paola Puccinelli, Cristoforo Incorvaia, Italian Cometa Study Group

Published in: Allergy, Asthma & Clinical Immunology | Issue 1/2017

Login to get access

Abstract

As standard drug treatment of allergic rhinitis (AR) is not completely satisfactory, allergen immunotherapy (AIT) represents the only current treatment with the potential to modify the natural history. House dust mite (HDM) allergy is very common. The aim of the current experience was to describe the clinical profile of HDM-allergic patients with AR who received AIT in a real world model, such as allergy clinics. Globally, 239 patients (126 adults and 113 children; 107 females and 132 males; mean age 21 years, age range 6–56 years) were evaluated. AIT was prescribed in 59 patients (24.7%), 44 adults (35%) and 15 children (13.3%). The current findings deriving from this real world multicentre study are consistent with previous investigations on HDM-AIT and define some clinical characteristics of the eligible candidate to this treatment. In fact, severity of ocular-nasal symptoms and over-use of symptomatic medications may typify the ideal candidate to HDM-AIT and SLIT was the preferred choice.
Literature
1.
go back to reference Bernstein DI, Schwartz G, Bernstein JA. Allergic rhinitis: mechanisms and treatment. Immunol Allergy Clin North Am. 2016;36(2):261–78.CrossRefPubMed Bernstein DI, Schwartz G, Bernstein JA. Allergic rhinitis: mechanisms and treatment. Immunol Allergy Clin North Am. 2016;36(2):261–78.CrossRefPubMed
2.
go back to reference Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen). Allergy. 2008;63(Suppl. 86):8–160.CrossRefPubMed Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen). Allergy. 2008;63(Suppl. 86):8–160.CrossRefPubMed
3.
go back to reference Durham SR, Penagos M. Sublingual or subcutaneous immunotherapy for allergic rhinitis? J Allergy Clin Immunol. 2016;137(2):339–49.CrossRefPubMed Durham SR, Penagos M. Sublingual or subcutaneous immunotherapy for allergic rhinitis? J Allergy Clin Immunol. 2016;137(2):339–49.CrossRefPubMed
4.
go back to reference Calderon MA, Casale TB, Nelson HS, Demoly P. An evidence-based analysis of house dust mite allergen immunotherapy: a call for more rigorous clinical studies. J Allergy Clin Immunol. 2013;132(6):1322–36.CrossRefPubMed Calderon MA, Casale TB, Nelson HS, Demoly P. An evidence-based analysis of house dust mite allergen immunotherapy: a call for more rigorous clinical studies. J Allergy Clin Immunol. 2013;132(6):1322–36.CrossRefPubMed
5.
go back to reference Ciprandi G, Incorvaia C, Masieri S, Buttafava S, Frati F. The best allergen immunotherapy choice for mite allergic patients. Expert Rev Clin Immunol. 2016;12(6):603–4.CrossRefPubMed Ciprandi G, Incorvaia C, Masieri S, Buttafava S, Frati F. The best allergen immunotherapy choice for mite allergic patients. Expert Rev Clin Immunol. 2016;12(6):603–4.CrossRefPubMed
6.
go back to reference Karaman S, Can D, Erdem SB, Nacaroglu HT, Karkiner CS, Gunay I. Is there any parameter helpful for predicting a suitable candidate for mite immunotherapy? Iran J Allergy Asthma Immunol. 2016;15(2):105–11.PubMed Karaman S, Can D, Erdem SB, Nacaroglu HT, Karkiner CS, Gunay I. Is there any parameter helpful for predicting a suitable candidate for mite immunotherapy? Iran J Allergy Asthma Immunol. 2016;15(2):105–11.PubMed
7.
go back to reference Platts-Mills TA, Hayden ML, Chapman MD, Wilkins SR. Seasonal variation in dust mite and grass-pollen allergens in dust from the houses of patients with asthma. J Allergy Clin Immunol. 1987;79:781–91.CrossRefPubMed Platts-Mills TA, Hayden ML, Chapman MD, Wilkins SR. Seasonal variation in dust mite and grass-pollen allergens in dust from the houses of patients with asthma. J Allergy Clin Immunol. 1987;79:781–91.CrossRefPubMed
8.
go back to reference Gelardi M, Peroni DG, Incorvaia C, Quaranta N, De Luca C, Barberi S, et al. Seasonal changes in nasal cytology in mite-allergic patients. J Inflamm Res. 2014;7:39–44.PubMedPubMedCentral Gelardi M, Peroni DG, Incorvaia C, Quaranta N, De Luca C, Barberi S, et al. Seasonal changes in nasal cytology in mite-allergic patients. J Inflamm Res. 2014;7:39–44.PubMedPubMedCentral
9.
go back to reference Leatherman B, Skoner DP, Hadley JA, Walstein N, Blaiss MS, Dykewicz MS, Craig T, Smith N, Allen-Ramey F. The Allergies, Immunotherapy, and RhinoconjunctivitiS (AIRS) survey: provider practices and beliefs about allergen immunotherapy. Int Forum Allergy Rhinol. 2014;4(10):779–88.CrossRefPubMed Leatherman B, Skoner DP, Hadley JA, Walstein N, Blaiss MS, Dykewicz MS, Craig T, Smith N, Allen-Ramey F. The Allergies, Immunotherapy, and RhinoconjunctivitiS (AIRS) survey: provider practices and beliefs about allergen immunotherapy. Int Forum Allergy Rhinol. 2014;4(10):779–88.CrossRefPubMed
10.
go back to reference Lynch SV, Wood RA, Boushey H, Bacharier LB, Bloomberg GR, Kattan M, et al. Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol. 2014;134(3):593–601.CrossRefPubMedPubMedCentral Lynch SV, Wood RA, Boushey H, Bacharier LB, Bloomberg GR, Kattan M, et al. Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol. 2014;134(3):593–601.CrossRefPubMedPubMedCentral
Metadata
Title
Allergic rhinitis: the eligible candidate to mite immunotherapy in the real world
Authors
Giorgio Ciprandi
Valentina Natoli
Paola Puccinelli
Cristoforo Incorvaia
Italian Cometa Study Group
Publication date
01-12-2017
Publisher
BioMed Central
Published in
Allergy, Asthma & Clinical Immunology / Issue 1/2017
Electronic ISSN: 1710-1492
DOI
https://doi.org/10.1186/s13223-017-0185-x

Other articles of this Issue 1/2017

Allergy, Asthma & Clinical Immunology 1/2017 Go to the issue