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Trials
Published in: Trials 1/2015

Open Access 01-12-2015 | Study protocol

Engaging teenagers in improving their health behaviours and increasing their interest in science (Evaluation of LifeLab Southampton): study protocol for a cluster randomized controlled trial

Authors: Kathryn Woods-Townsend, Lisa Bagust, Mary Barker, Andri Christodoulou, Hannah Davey, Keith Godfrey, Marcus Grace, Janice Griffiths, Mark Hanson, Hazel Inskip

Published in: Trials | Issue 1/2015

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Abstract

Background

Lifestyle and health behaviours are strongly linked to non-communicable disease risk, but modifying them is challenging. There is an increasing recognition that adolescence is an important time for lifestyle and health behaviours to become embedded. Improving these behaviours in adolescents is important not only for their own health but also for that of their future children. LifeLab Southampton has been developed as a purpose-built classroom and laboratory in University Hospital Southampton. Secondary school students visit LifeLab to learn how childhood, adolescent and parental nutrition influences health, understand the impact of their lifestyle on their cardiovascular and metabolic health, and to inspire them with the excitement of research and future career possibilities in science. The LifeLab visit is part of a programme of work linked to the English National Curriculum. Pilot work has indicated that attitudes towards health can be changed by such LifeLab sessions.

Methods/Design

A cluster randomised controlled trial is being conducted to evaluate the effectiveness of the LifeLab intervention, the primary outcome being a measurement of the change in nutrition, health and lifestyle literacy from before to after the LifeLab intervention.
The LifeLab intervention comprises professional development for the teachers involved; preparatory lessons for the school students, delivered in school; a hands-on practical day at LifeLab, including a ‘Meet the Scientist’ session; post-visit lessons delivered in school; and the opportunity to participate in the annual LifeLab Schools’ Conference. This study aims to recruit approximately 2,500 secondary school students aged 13 to 14 years from 32 schools (the clusters) from Southampton and neighbouring areas. Participating schools will be randomised to control or intervention groups. The intervention will be run over two academic school years, with baseline questionnaire data collected from students at participating schools at the start of the academic year and follow- up questionnaire data collected approximately 12 months later.

Trial registration

Evaluation of LifeLab is a cluster randomised controlled trial (ISRCTN71951436, registered 25 March 2015), funded by the British Heart Foundation (PG/14/33/30827).
Appendix
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Literature
1.
2.
Hanson M, Gluckman P, Nutbeam D, Hearn J. Priority actions for the non-communicable disease crisis. Lancet. 2011;378:566–7.CrossRefPubMed
3.
Low FM, Gluckman PD, Hanson MA. Developmental plasticity and epigenetic mechanisms underpinning metabolic and cardiovascular diseases. Epigenomics. 2011;3:279–94.CrossRefPubMed
4.
5.
Sawyer SM, Afifi RA, Bearinger LH, Blakemore SJ, Dick B, Ezeh AC, et al. Adolescence: a foundation for future health. Lancet. 2012;379:1630–40.CrossRefPubMed
6.
Inskip HM, Godfrey KM, Robinson SM, Law CM, Barker DJ, Cooper C. Cohort profile: the Southampton women’s survey. Int J Epidemiol. 2006;35:42–8.CrossRefPubMed
7.
8.
9.
Robinson SM, Crozier SR, Borland SE, Hammond J, Barker DJ, Inskip HM. Impact of educational attainment on the quality of young women’s diets. Eur J Clin Nutr. 2004;58:1174–80.CrossRefPubMed
10.
Wilkinson R, Inskip H. The health and wellbeing of women in Southampton’s communities: an analysis of the Southampton women’s survey. 2006.
11.
Crozier SR, Robinson SM, Godfrey KM, Cooper C, Inskip HM. Women’s dietary patterns change little from before to during pregnancy. J Nutr. 2009;139:1956–63.CrossRefPubMedPubMedCentral
12.
Inskip HM, Crozier SR, Godfrey KM, Borland SE, Cooper C, Robinson SM. Women’s compliance with nutrition and lifestyle recommendations before pregnancy: general population cohort study. BMJ. 2009;338:b481.CrossRefPubMedPubMedCentral
13.
Robinson SM, Marriott LD, Crozier SR, Harvey NC, Gale CR, Inskip HM, et al. Variations in infant feeding practice are associated with body composition in childhood: a prospective cohort study. J Clin Endocrinol Metab. 2009;94:2799–805.CrossRefPubMed
14.
Robinson S, Marriott L, Poole J, Crozier S, Borland S, Lawrence W, et al. Dietary patterns in infancy: the importance of maternal and family influences on feeding practice. Br J Nutr. 2007;98:1029–37.CrossRefPubMed
15.
Gale CR, Martyn CN, Marriott LD, Limond J, Crozier S, Inskip HM, et al. Dietary patterns in infancy and cognitive and neuropsychological function in childhood. J Child Psychol Psychiatry. 2009;50:816–23.CrossRefPubMedPubMedCentral
16.
Brazionis L, Golley RK, Mittinty MN, Smithers LG, Emmett P, Northstone K, et al. Diet spanning infancy and toddlerhood is associated with child blood pressure at age 7.5 y. Am J Clin Nutr. 2013;97:1375–86.CrossRefPubMed
17.
Golley RK, Smithers LG, Mittinty MN, Emmett P, Northstone K, Lynch JW. Diet quality of U.K. infants is associated with dietary, adiposity, cardiovascular, and cognitive outcomes measured at 7–8 years of age. J Nutr. 2013;143:1611–7.CrossRefPubMed
18.
Barker M, Lawrence WT, Skinner TC, Haslam CO, Robinson SM, Inskip HM, et al. Constraints on food choices of women in the UK with lower educational attainment. Public Health Nutr. 2008;11:1229–37.CrossRefPubMed
19.
Cooper C, Eriksson JG, Forsen T, Osmond C, Tuomilehto J, Barker DJ. Maternal height, childhood growth and risk of hip fracture in later life: a longitudinal study. Osteoporos Int. 2001;12:623–9.CrossRefPubMed
20.
Godfrey KM, Gluckman PD, Hanson MA. Developmental origins of metabolic disease: life course and intergenerational perspectives. Trends Endocrinol Metab. 2010;21:199–205.CrossRefPubMed
21.
Barker DJP. Mothers, Babies and health in later life. Edinburgh: Churchill Livingstone; 1998.
22.
Eriksson JG, Forsen T, Tuomilehto J, Osmond C, Barker DJ. Early growth and coronary heart disease in later life: longitudinal study. BMJ. 2001;322:949–53.CrossRefPubMedPubMedCentral
23.
Gluckman PD, Hanson MA, Bateson P, Beedle AS, Law CM, Bhutta ZA, et al. Towards a new developmental synthesis: adaptive developmental plasticity and human disease. Lancet. 2009;373:1654–7.CrossRefPubMed
24.
Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med. 2008;359:61–73.CrossRefPubMedPubMedCentral
25.
Pike KC, Hanson MA, Godfrey KM. Developmental mismatch: consequences for later cardiorespiratory health. BJOG. 2008;115:149–57.CrossRefPubMed
26.
Inskip H, Baird J, Barker M, Briley AL, D’Angelo S, Grote V, et al. Influences on adherence to diet and physical activity recommendations in women and children: insights from six European studies. Ann Nutr Metab. 2014;64:332–9.CrossRefPubMedPubMedCentral
27.
28.
Ratzan SC. Health competent societies: our challenge and future. J Health Commun. 2009;14:99–101.CrossRefPubMed
29.
Siegel H. Why should educators care about argumentation? Informal Logic. 1995;17:159–76.
30.
Millar R, Osbourne J. Beyond 2000: Science Education for the Future. King’s College London, School of Education;1998.
31.
Roberts DA. Scientific Literacy/Science Literacy. In Handbook of Research on Science Education. Edited by Abell SK, Lederman NG. Lawrence Erlbaum Associates Inc: New Jersey, USA;2006:729–80.
32.
Baird J, Cooper C, Margetts BM, Barker M, Inskip HM. Changing health behaviour of young women from disadvantaged backgrounds: evidence from systematic reviews. Proc Nutr Soc. 2009;68:195–204.CrossRefPubMed
33.
Borzekowski DL. Considering children and health literacy: a theoretical approach. Pediatrics. 2009;124 Suppl 3:S282–8.CrossRefPubMed
34.
Nutbeam D. Getting evidence into policy and practice to address health inequalities. Health Promot Int. 2004;19:137–40.CrossRefPubMed
35.
36.
Ofsted. Learning outside the classroom - How far should you go? 2008.
37.
Grace M, Woods-Townsend K, Griffiths J, Godfrey K, Hanson M, Galloway I, et al. A science-based approach to developing teenagers’ views on their health and the health of their future children. Health Educ. 2012;112:543–59.CrossRef
38.
Department for Education and Skills. Learning Outside the Classroom Manifesto. London: DfES; 2006.
39.
O’Donnell L, Morris M, Wilson R. Education Outside the Classroom: an Assessment of Activity and Practice in Schools and Local Authorities. In: DfES Research Report 803. London: DfEs; 2006.
40.
Braund M, Reiss M. Towards a more authentic science curriculum: the contribution of out-of-school learning. Int J Sci Educ. 2006;28:1373–88.CrossRef
41.
Bagust L, Davey H, Woods-Townsend K. LifeLab: Me, My Health and My Children’s Health. University of Southampton. 2014.
42.
Guttersrud O, Dalane JO, Pettersen S. Improving measurement in nutrition literacy research using Rasch modelling: examining construct validity of stage-specific ‘critical nutrition literacy’ scales. Public Health Nutr. 2014;17:877–83.CrossRefPubMed
43.
Crozier SR, Inskip HM, Barker ME, Lawrence WT, Cooper C, Robinson SM. Development of a 20-item food frequency questionnaire to assess a ‘prudent’ dietary pattern among young women in Southampton. Eur J Clin Nutr. 2010;64:99–104.CrossRefPubMed
44.
Linnan L, Steckler A. Process Evaluation for Public Health Interventions and Research. San Francisco: John Wiley and Sons; 2002.
45.
Moore G, Audrey S, Barker M, Bond L, Bonell C, Cooper C, et al. Process evaluation in complex public health intervention studies: the need for guidance. J Epidemiol Community Health. 2014;68:101–2.CrossRefPubMed
46.
Moore GF, Audrey S, Barker M, Bond L, Bonell C, Hardeman W, et al. Process evaluation of complex interventions: Medical Research Council guidance. BMJ. 2015;350:h1258.CrossRefPubMedPubMedCentral
47.
48.
Bay JL, Mora HA, Sloboda DM, Morton SM, Vickers MH, Gluckman PD. Adolescent understanding of DOHaD concepts: a school-based intervention to support knowledge translation and behaviour change. J Dev Orig Health Dis. 2012;3:469–82.CrossRefPubMed
49.
Metadata
Title
Engaging teenagers in improving their health behaviours and increasing their interest in science (Evaluation of LifeLab Southampton): study protocol for a cluster randomized controlled trial
Authors
Kathryn Woods-Townsend
Lisa Bagust
Mary Barker
Andri Christodoulou
Hannah Davey
Keith Godfrey
Marcus Grace
Janice Griffiths
Mark Hanson
Hazel Inskip
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Trials / Issue 1/2015
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/s13063-015-0890-z

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