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Journal of Ovarian Research
Published in: Journal of Ovarian Research 1/2015

Open Access 01-12-2015 | Review

Use of aromatase inhibitors in practice of gynecology

Authors: Betul Usluogullari, Candan Zehra Duvan, Celil Alper Usluogullari

Published in: Journal of Ovarian Research | Issue 1/2015

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Abstract

Purpose

The conversion of androgens into estrogens by aromatase is called aromatization and is inhibited by aromatase inhibitors (AIs). The aim of this article is to evaluate the use of aromatase inhibitors in gynecological diseases such as endometriosis, leiomyoma, estrogen- dependent gynecologic neoplasia and infertility.

Methods

This is a review of literature combined with experience and use of aromatase ınhıbıtors ın practıce of gynecology.

Conclusion

AIs are promising agents in treatment of estrogen dependent disease. However lack of experience, side effects and cost are limiting factors for using these agents in infertility treatment. However there is need for larger, well designed randomized trials to generate robust data in order to establish the true potential of aromatase inhibitors.
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Metadata
Title
Use of aromatase inhibitors in practice of gynecology
Authors
Betul Usluogullari
Candan Zehra Duvan
Celil Alper Usluogullari
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Journal of Ovarian Research / Issue 1/2015
Electronic ISSN: 1757-2215
DOI
https://doi.org/10.1186/s13048-015-0131-9

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