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Journal of Hematology & Oncology
Published in: Journal of Hematology & Oncology 1/2016

Open Access 01-12-2016 | Review

The clinical application of mesenchymal stromal cells in hematopoietic stem cell transplantation

Authors: Ke Zhao, Qifa Liu

Published in: Journal of Hematology & Oncology | Issue 1/2016

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Abstract

Mesenchymal stromal cells (MSCs) are multipotent stem cells well known for repairing tissue, supporting hematopoiesis, and modulating immune and inflammation response. These outstanding properties make MSCs as an attractive candidate for cellular therapy in immune-based disorders, especially hematopoietic stem cell transplantation (HSCT). In this review, we outline the progress of MSCs in preventing and treating engraftment failure (EF), graft-versus-host disease (GVHD) following HSCT and critically discuss unsolved issues in clinical applications.
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Metadata
Title
The clinical application of mesenchymal stromal cells in hematopoietic stem cell transplantation
Authors
Ke Zhao
Qifa Liu
Publication date
01-12-2016
Publisher
BioMed Central
Published in
Journal of Hematology & Oncology / Issue 1/2016
Electronic ISSN: 1756-8722
DOI
https://doi.org/10.1186/s13045-016-0276-z

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