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Journal of Orthopaedic Surgery and Research

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Open Access 01-12-2018 | Research article

Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers

Authors: Sebastian Philipp Boelch, Manuel Weissenberger, Frederik Spohn, Maximilian Rudert, Martin Luedemann

Published in: Journal of Orthopaedic Surgery and Research | Issue 1/2018

Abstract

Background

Evaluation of infection persistence during the two-stage exchange of the hip is challenging. Joint aspiration before reconstruction is supposed to rule out infection persistence. Sensitivity and specificity of synovial fluid culture and synovial leucocyte count for detecting infection persistence during the two-stage exchange of the hip were evaluated.

Methods

Ninety-two aspirations before planned joint reconstruction during the two-stage exchange with spacers of the hip were retrospectively analyzed.

Results

The sensitivity and specificity of synovial fluid culture was 4.6 and 94.3%. The sensitivity and specificity of synovial leucocyte count at a cut-off value of 2000 cells/μl was 25.0 and 96.9%. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) values were significantly higher before prosthesis removal and reconstruction or spacer exchange (p = 0.00; p = 0.013 and p = 0.039; p = 0.002) in the infection persistence group. Receiver operating characteristic area under the curve values before prosthesis removal and reconstruction or spacer exchange for ESR were lower (0.516 and 0.635) than for CRP (0.720 and 0.671).

Conclusions

Synovial fluid culture and leucocyte count cannot rule out infection persistence during the two-stage exchange of the hip.

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Title: Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers
Authors: Sebastian Philipp Boelch
Manuel Weissenberger
Frederik Spohn
Maximilian Rudert
Martin Luedemann
Publication date: 01-12-2018
Publisher: BioMed Central
Published in: Journal of Orthopaedic Surgery and Research / Issue 1/2018
Electronic ISSN: 1749-799X
DOI: https://doi.org/10.1186/s13018-017-0703-z

2024 ASCO Annual Meeting

Springer Medicine

Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers

Abstract

Background

Methods

Results

Conclusions

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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