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Published in: Human Resources for Health 1/2022

Open Access 01-12-2022 | Medroxyprogesterone Acetate | Research

Provision of injectable contraceptives by community health workers in sub-Saharan Africa: a systematic review of safety, acceptability and effectiveness

Authors: Besong Eric Ayuk, Brenda Mbouamba Yankam, Farrukh Ishaque Saah, Luchuo Engelbert Bain

Published in: Human Resources for Health | Issue 1/2022

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Abstract

Background

Injectable contraceptives are the most popular method of contraception in sub-Saharan Africa (SSA), but their availability in clinical settings has been severely limited, despite the scarcity of health care providers and limited access to health facilities. WHO and USAID have endorsed the community-based distribution of injectable contraceptives as a promising option for improving access to family planning services and expanding the method mix for women who want to limit the number of births. Studies have shown that community health workers (CHWs) can provide women with injectable contraceptives that meet acceptable quality standards. The goal of this study is to identify, evaluate and synthesize evidence supporting the use of community-based administration of injectable contraceptives in SSA.

Methods

This review's guidance was based on a previously developed protocol. Nine international electronic databases and the websites of organizations known to support community-based reproductive health initiatives in SSA were searched systemically. Experts in this area were also contacted for the identification of unpublished literature and ongoing studies. The reference lists of eligible studies were reviewed. The Effective Public Practice Project tool was used to assess the quality and risk of bias in eligible studies. Data were extracted and analysed using a custom data extraction form and a narrative synthesis.

Results

The search strategy identified a total of 1358 studies with 12 studies meeting the inclusion criteria. One unpublished study was provided by an expert making a total of 13 studies. The results showed that irrespective of the study designs, well-trained CHWs can competently administer injectable contraceptives safely and community-based delivery of injectable contraceptives is acceptable in SSA. Also, the use of community health workers in the provision of depot-medroxyprogesterone acetate expanded access to inhabitants of hard-to-reach areas and led to an overall uptake of injectable contraceptives as well as family planning. Studies that compared CHWs to clinic-based providers revealed equivalent or higher levels of performance in favour of CHWs.

Conclusions

The CHWs can competently provide injectable contraceptives within SSA communities if appropriately trained and supervised. Hence, SSA policymakers should give this initiative due consideration as a way of improving access to family planning services.
Literature
2.
go back to reference Tran NT, Seuc A, Tshikaya B, Mutuale M, Landoulsi S, Kini B, Nkolomonyi BM, Kyloka JN, Langwana F, Cuzin-Kihl A, Kiarie J. Effectiveness of post-partum family planning interventions on contraceptive use and method mix at 1 year after childbirth in Kinshasa, DR Congo (Yam Daabo): a single-blind, cluster-randomised controlled trial. Lancet Glob Health. 2020;8(3):e399-410.CrossRef Tran NT, Seuc A, Tshikaya B, Mutuale M, Landoulsi S, Kini B, Nkolomonyi BM, Kyloka JN, Langwana F, Cuzin-Kihl A, Kiarie J. Effectiveness of post-partum family planning interventions on contraceptive use and method mix at 1 year after childbirth in Kinshasa, DR Congo (Yam Daabo): a single-blind, cluster-randomised controlled trial. Lancet Glob Health. 2020;8(3):e399-410.CrossRef
3.
go back to reference Malarcher S, Meirik O, Lebetkin E, Shah I, Spieler J, Stanback J. Provision of DMPA by community health workers: what the evidence shows. Contraception. 2011;83(6):495–503.CrossRef Malarcher S, Meirik O, Lebetkin E, Shah I, Spieler J, Stanback J. Provision of DMPA by community health workers: what the evidence shows. Contraception. 2011;83(6):495–503.CrossRef
4.
go back to reference Okegbe T, Affo J, Djihoun F, Zannou A, Hounyo O, Ahounou G, Bangbola KA, Harris N. Introduction of community-based provision of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) in Benin: programmatic results. Global Health Sci Pract. 2019;7(2):228–39.CrossRef Okegbe T, Affo J, Djihoun F, Zannou A, Hounyo O, Ahounou G, Bangbola KA, Harris N. Introduction of community-based provision of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) in Benin: programmatic results. Global Health Sci Pract. 2019;7(2):228–39.CrossRef
5.
go back to reference Reiss K, Penfold S, Alabi O, Ali M, Hopkins K, Ngo TD, Odogwu K, Douthwaite M, Ezire O, Udoh U, Effiom E. Safety, quality, and acceptability of contraceptive subdermal implant provision by community health extension workers versus nurses and midwives in Nigeria: protocol for a quasi-experimental, noninferiority study. JMIR Res Protocols. 2018;7(3): e8721.CrossRef Reiss K, Penfold S, Alabi O, Ali M, Hopkins K, Ngo TD, Odogwu K, Douthwaite M, Ezire O, Udoh U, Effiom E. Safety, quality, and acceptability of contraceptive subdermal implant provision by community health extension workers versus nurses and midwives in Nigeria: protocol for a quasi-experimental, noninferiority study. JMIR Res Protocols. 2018;7(3): e8721.CrossRef
7.
go back to reference Bongaarts J, Cleland JC, Townsend J, Bertrand JT, Gupta MD. Family planning programs for the 21st century: rationale and design. 2012. Bongaarts J, Cleland JC, Townsend J, Bertrand JT, Gupta MD. Family planning programs for the 21st century: rationale and design. 2012.
8.
go back to reference Jain J, Dutton C, Nicosia A, Wajszczuk C, Bode FR, Mishell DR Jr. Pharmacokinetics, ovulation suppression and return to ovulation following a lower dose subcutaneous formulation of Depo-Provera®. Contraception. 2004;70(1):11–8.CrossRef Jain J, Dutton C, Nicosia A, Wajszczuk C, Bode FR, Mishell DR Jr. Pharmacokinetics, ovulation suppression and return to ovulation following a lower dose subcutaneous formulation of Depo-Provera®. Contraception. 2004;70(1):11–8.CrossRef
9.
go back to reference Stout A, Wood S, Barigye G, Kaboré A, Siddo D, Ndione I. Expanding access to injectable contraception: results from pilot introduction of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) in 4 African countries. Global Health Sci Pract. 2018;6(1):55–72.CrossRef Stout A, Wood S, Barigye G, Kaboré A, Siddo D, Ndione I. Expanding access to injectable contraception: results from pilot introduction of subcutaneous depot medroxyprogesterone acetate (DMPA-SC) in 4 African countries. Global Health Sci Pract. 2018;6(1):55–72.CrossRef
10.
go back to reference Weidert K, Gessessew A, Bell S, Godefay H, Prata N. Community health workers as social marketers of injectable contraceptives: a case study from Ethiopia. Global Health Sci Pract. 2017;5(1):44–56.CrossRef Weidert K, Gessessew A, Bell S, Godefay H, Prata N. Community health workers as social marketers of injectable contraceptives: a case study from Ethiopia. Global Health Sci Pract. 2017;5(1):44–56.CrossRef
13.
go back to reference Sheff MC, Jackson EF, Kanté AM, Rusibamayila A, Phillips JF. The impact of adding community-based distribution of oral contraceptives and condoms to a cluster randomized primary health care intervention in rural Tanzania. Reprod Health. 2019;16(1):1–2.CrossRef Sheff MC, Jackson EF, Kanté AM, Rusibamayila A, Phillips JF. The impact of adding community-based distribution of oral contraceptives and condoms to a cluster randomized primary health care intervention in rural Tanzania. Reprod Health. 2019;16(1):1–2.CrossRef
14.
go back to reference Mwembo A, Emel R, Koba T, Sankoko JB, Ngay A, Gay R, Bertrand JT. Acceptability of the distribution of DMPA-SC by community health workers among acceptors in the rural province of Lualaba in the Democratic Republic of the Congo: a pilot study. Contraception. 2018;98(5):454–9.CrossRef Mwembo A, Emel R, Koba T, Sankoko JB, Ngay A, Gay R, Bertrand JT. Acceptability of the distribution of DMPA-SC by community health workers among acceptors in the rural province of Lualaba in the Democratic Republic of the Congo: a pilot study. Contraception. 2018;98(5):454–9.CrossRef
15.
go back to reference Chin-Quee D, Bratt J, Malkin M, Nduna MM, Otterness C, Jumbe L, Mbewe RK. Building on safety, feasibility, and acceptability: the impact and cost of community health worker provision of injectable contraception. Global Health Sci Pract. 2013;1(3):316–27.CrossRef Chin-Quee D, Bratt J, Malkin M, Nduna MM, Otterness C, Jumbe L, Mbewe RK. Building on safety, feasibility, and acceptability: the impact and cost of community health worker provision of injectable contraception. Global Health Sci Pract. 2013;1(3):316–27.CrossRef
17.
go back to reference Comfort AB, Chankova S, Juras R, Hsi CN, Peterson LA, Hathi P. Providing free pregnancy test kits to community health workers increases distribution of contraceptives: results from an impact evaluation in Madagascar. Contraception. 2016;93(1):44–51.CrossRef Comfort AB, Chankova S, Juras R, Hsi CN, Peterson LA, Hathi P. Providing free pregnancy test kits to community health workers increases distribution of contraceptives: results from an impact evaluation in Madagascar. Contraception. 2016;93(1):44–51.CrossRef
18.
go back to reference Hoke T, Brunie A, Krueger K, Dreisbach C, Akol A, Rabenja NL, Olawo A, Stanback J. Community-based distribution of injectable contraceptives: introduction strategies in four sub-Saharan African countries. Int Perspect Sex Reprod Health. 2012;38(4):214–9.CrossRef Hoke T, Brunie A, Krueger K, Dreisbach C, Akol A, Rabenja NL, Olawo A, Stanback J. Community-based distribution of injectable contraceptives: introduction strategies in four sub-Saharan African countries. Int Perspect Sex Reprod Health. 2012;38(4):214–9.CrossRef
19.
go back to reference Stanback J, Mbonye AK, Bekiita M. Contraceptive injections by community health workers in Uganda: a nonrandomized community trial. Bull World Health Organ. 2007;85:768–73.CrossRef Stanback J, Mbonye AK, Bekiita M. Contraceptive injections by community health workers in Uganda: a nonrandomized community trial. Bull World Health Organ. 2007;85:768–73.CrossRef
20.
go back to reference Poss C, Stanback J, Mbonye KA, Bekiita M, Otterness C, Mwebesa W. Analysis of long-term outcomes of injectable contraceptive users in Nakasongola, Uganda. Unpublished manuscript. 2009. Poss C, Stanback J, Mbonye KA, Bekiita M, Otterness C, Mwebesa W. Analysis of long-term outcomes of injectable contraceptive users in Nakasongola, Uganda. Unpublished manuscript. 2009.
21.
go back to reference Prata N, Gessessew A, Cartwright A, Fraser A. Provision of injectable contraceptives in Ethiopia through community-based reproductive health agents. Bull World Health Organ. 2011;89:556–64.CrossRef Prata N, Gessessew A, Cartwright A, Fraser A. Provision of injectable contraceptives in Ethiopia through community-based reproductive health agents. Bull World Health Organ. 2011;89:556–64.CrossRef
22.
go back to reference Jacinto A, Mobaracaly MR, Ustáb MB, Bique C, Blazer C, Weidert K, Prata N. Safety and acceptability of community-based distribution of injectable contraceptives: a pilot project in Mozambique. Global Health Sci Pract. 2016;4(3):410–21.CrossRef Jacinto A, Mobaracaly MR, Ustáb MB, Bique C, Blazer C, Weidert K, Prata N. Safety and acceptability of community-based distribution of injectable contraceptives: a pilot project in Mozambique. Global Health Sci Pract. 2016;4(3):410–21.CrossRef
23.
go back to reference Olawo AA, Bashir I, Solomon M, Stanback J, Ndugga BM, Malonza I. “A cup of tea with our CBD agent…”: community provision of injectable contraceptives in Kenya is safe and feasible. Global Health Sci Pract. 2013;1(3):308–15.CrossRef Olawo AA, Bashir I, Solomon M, Stanback J, Ndugga BM, Malonza I. “A cup of tea with our CBD agent…”: community provision of injectable contraceptives in Kenya is safe and feasible. Global Health Sci Pract. 2013;1(3):308–15.CrossRef
25.
go back to reference Krueger K, Akol A, Wamala P, Brunie A. Scaling up community provision of injectables through the public sector in Uganda. Stud Fam Plann. 2011;42(2):117–24.CrossRef Krueger K, Akol A, Wamala P, Brunie A. Scaling up community provision of injectables through the public sector in Uganda. Stud Fam Plann. 2011;42(2):117–24.CrossRef
26.
go back to reference Riedel EM, Turner DT, Kobeissi LH, Karyotaki E, Say L, Cuijpers P. The impact of psychosocial interventions on condom and contraceptive use in LMICs: meta-analysis of randomised controlled trials. Glob Public Health. 2020;15(8):1182–99.CrossRef Riedel EM, Turner DT, Kobeissi LH, Karyotaki E, Say L, Cuijpers P. The impact of psychosocial interventions on condom and contraceptive use in LMICs: meta-analysis of randomised controlled trials. Glob Public Health. 2020;15(8):1182–99.CrossRef
28.
go back to reference Malarcher S. A review of the evidence developed for a technical consultation on expanding access to injectable contraception. Family Health International. 2009. Malarcher S. A review of the evidence developed for a technical consultation on expanding access to injectable contraception. Family Health International. 2009.
29.
go back to reference Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;2:349. Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation. BMJ. 2015;2:349.
30.
go back to reference Lewin S, Munabi‐Babigumira S, Glenton C, Daniels K, Bosch‐Capblanch X, Van Wyk BE, Odgaard‐Jensen J, Johansen M, Aja GN, Zwarenstein M, Scheel IB. Lay health workers in primary and community health care for maternal and child health and the management of infectious diseases. Cochrane Database Syst Rev. 2010(3). Lewin S, Munabi‐Babigumira S, Glenton C, Daniels K, Bosch‐Capblanch X, Van Wyk BE, Odgaard‐Jensen J, Johansen M, Aja GN, Zwarenstein M, Scheel IB. Lay health workers in primary and community health care for maternal and child health and the management of infectious diseases. Cochrane Database Syst Rev. 2010(3).
31.
go back to reference Draper BH, Morroni C, Hoffman MN, Smit JA, Beksinska ME, Hapgood JP, Van der Merwe L. Depot medroxyprogesterone versus Norethisterone oenanthate for long‐acting progestogenic contraception. Cochrane Database Syst Rev. 2006(3). Draper BH, Morroni C, Hoffman MN, Smit JA, Beksinska ME, Hapgood JP, Van der Merwe L. Depot medroxyprogesterone versus Norethisterone oenanthate for long‐acting progestogenic contraception. Cochrane Database Syst Rev. 2006(3).
32.
go back to reference World Health Organization, World Health Organization. Reproductive Health. Medical eligibility criteria for contraceptive use. World Health Organization; 2010. World Health Organization, World Health Organization. Reproductive Health. Medical eligibility criteria for contraceptive use. World Health Organization; 2010.
33.
go back to reference Thomas H. Quality assessment tool for quantitative studies. Effective public health practice project. Hamilton, ON, Canada: McMaster University. 2003. Thomas H. Quality assessment tool for quantitative studies. Effective public health practice project. Hamilton, ON, Canada: McMaster University. 2003.
34.
go back to reference Armijo-Olivo S, Stiles CR, Hagen NA, Biondo PD, Cummings GG. Assessment of study quality for systematic reviews: a comparison of the Cochrane Collaboration Risk of Bias Tool and the Effective Public Health Practice Project Quality Assessment Tool: methodological research. J Eval Clin Pract. 2012;18(1):12–8.CrossRef Armijo-Olivo S, Stiles CR, Hagen NA, Biondo PD, Cummings GG. Assessment of study quality for systematic reviews: a comparison of the Cochrane Collaboration Risk of Bias Tool and the Effective Public Health Practice Project Quality Assessment Tool: methodological research. J Eval Clin Pract. 2012;18(1):12–8.CrossRef
35.
go back to reference Deeks JJ, Dinnes J, D’Amico R, Sowden AJ, Sakarovitch C, Song F, Petticrew M, Altman DG. Evaluating non-randomised intervention studies. Health Technol Assess (Winchester, England). 2003;7(27):iii–173. Deeks JJ, Dinnes J, D’Amico R, Sowden AJ, Sakarovitch C, Song F, Petticrew M, Altman DG. Evaluating non-randomised intervention studies. Health Technol Assess (Winchester, England). 2003;7(27):iii–173.
37.
go back to reference Popay J, Roberts H, Sowden A, Petticrew M, Arai L, Rodgers M, Britten N, Roen K, Duffy S. Guidance on the conduct of narrative synthesis in systematic reviews. A product from the ESRC methods programme Version. 2006; 1(1): b92 Popay J, Roberts H, Sowden A, Petticrew M, Arai L, Rodgers M, Britten N, Roen K, Duffy S. Guidance on the conduct of narrative synthesis in systematic reviews. A product from the ESRC methods programme Version. 2006; 1(1): b92
38.
go back to reference United Nations. "Political definition of "Major regions", according to the UN.". Archived from the original on 20 April 2010. Retrieved 10 June 2017. United Nations. "Political definition of "Major regions", according to the UN.". Archived from the original on 20 April 2010. Retrieved 10 June 2017.
39.
go back to reference Darroch JE, Singh S. Trends in contraceptive need and use in developing countries in 2003, 2008, and 2012: an analysis of national surveys. The Lancet. 2013;381(9879):1756–62.CrossRef Darroch JE, Singh S. Trends in contraceptive need and use in developing countries in 2003, 2008, and 2012: an analysis of national surveys. The Lancet. 2013;381(9879):1756–62.CrossRef
40.
go back to reference Shifting WT. Global recommendations and guidelines. Geneva: World Health Organization; 2008. Shifting WT. Global recommendations and guidelines. Geneva: World Health Organization; 2008.
41.
go back to reference Ramirez L. Introduction of a training program for the delivery of Depo-Provera® by community-based providers from the Ministry of Public Health in Guatemala (Proposal A25086) Informe narrativo de resultados. Centro de Investigación Epidemiológica en Salud Sexual y Reproductiva, Guatemala City, Guatemala. Unpublished project report. 2008. Ramirez L. Introduction of a training program for the delivery of Depo-Provera® by community-based providers from the Ministry of Public Health in Guatemala (Proposal A25086) Informe narrativo de resultados. Centro de Investigación Epidemiológica en Salud Sexual y Reproductiva, Guatemala City, Guatemala. Unpublished project report. 2008.
42.
go back to reference Tsui AO, Ochoa LH. The role of family planning programs as a fertility determinant. Service proximity as a determinant of contraceptive behavior: evidence from cross-National Studies of survey data. 1992. Tsui AO, Ochoa LH. The role of family planning programs as a fertility determinant. Service proximity as a determinant of contraceptive behavior: evidence from cross-National Studies of survey data. 1992.
Metadata
Title
Provision of injectable contraceptives by community health workers in sub-Saharan Africa: a systematic review of safety, acceptability and effectiveness
Authors
Besong Eric Ayuk
Brenda Mbouamba Yankam
Farrukh Ishaque Saah
Luchuo Engelbert Bain
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Human Resources for Health / Issue 1/2022
Electronic ISSN: 1478-4491
DOI
https://doi.org/10.1186/s12960-022-00763-8

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