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Cancer Cell International
Published in: Cancer Cell International 1/2022

Open Access 01-12-2022 | Colorectal Cancer | Review

Oncogenic roles of the lncRNA LINC00460 in human cancers

Authors: Min Su, Jinming Tang, Desong Yang, Zhining Wu, Qianjin Liao, Hui Wang, Yuhang Xiao, Wenxiang Wang

Published in: Cancer Cell International | Issue 1/2022

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Abstract

Long noncoding RNAs (lncRNAs) represent an important group of endogenous RNAs with limit protein-encoding capability, with a length of more than 200 nucleotides. Emerging evidence have demonstrated that lncRNAs are greatly involved in multiple cancers by playing critical roles in tumor initiation and progression. Long intergenic non-protein coding RNA 460 (LINC00460), a novel cancer-related lncRNA, exhibits abnormal expression and oncogenic function in multiple cancers, and positively correlates with poor clinical characteristics of cancer patients. LINC00460 has also been shown to be a promising biomarker for diagnosis as well as prognostic evaluation in cancer patients. In this review, we briefly summarized recent knowledge on the expression, functional roles, molecular mechanisms, and diagnostic and prognostic values of LINC00460 in human malignancies.
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Metadata
Title
Oncogenic roles of the lncRNA LINC00460 in human cancers
Authors
Min Su
Jinming Tang
Desong Yang
Zhining Wu
Qianjin Liao
Hui Wang
Yuhang Xiao
Wenxiang Wang
Publication date
01-12-2022
Publisher
BioMed Central
Published in
Cancer Cell International / Issue 1/2022
Electronic ISSN: 1475-2867
DOI
https://doi.org/10.1186/s12935-022-02655-2

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