Skip to main content
Top
Published in: BMC Health Services Research 1/2018

Open Access 01-12-2018 | Research article

Evaluation of a multicomponent pathway to address inpatient delirium on a neurosciences ward

Authors: Ethan G. Brown, S. Andrew Josephson, Noriko Anderson, Mary Reid, Melissa Lee, Vanja C. Douglas

Published in: BMC Health Services Research | Issue 1/2018

Login to get access

Abstract

Background

Delirium is a frequent and detrimental complication of inpatient hospitalization. Multicomponent intervention in selected groups has been shown to prevent and treat delirium, though little data exists on the effect of intervention in neurological patients. We studied the efficacy of a multicomponent delirium care pathway implemented on a largely neurology and neurosurgery hospital ward among unselected patients.

Methods

We incorporated a multicomponent delirium care pathway into the workflow of a university hospital for patients older than 50 years. The pathway involved risk-stratification for development of delirium, delirium screening, and non-pharmacologic behavioral prevention and intervention. We then retrospectively reviewed admissions before and after implementation of the care pathway. Our primary endpoint was incidence of delirium; secondary endpoints included delirium days, length of stay, restraint use, readmission rates, and discharge disposition.

Results

Seven hundred ninety eight admissions from before the delirium care pathway went into effect and 797 admissions from afterwards were reviewed. Baseline characteristics between groups were similar. Delirium incidence between the two groups did not change (7.0% before vs 7.2% after, p = 0.89). Length of stay among delirious patients significantly decreased after implementation of the delirium care pathway (9.60 before vs 7.06 after, β = − 0.16, adjusted p-value = 0.001).

Conclusion

Implementation of a delirium care pathway on a neurosciences ward was not associated with changes in the rate of delirium development, though length of stay among delirious patients decreased. In a largely neurologic population, multicomponent intervention to prevent and treat delirium may not change delirium incidence, but may be effective in mitigating delirium complications.
Literature
1.
go back to reference Inouye SK, Bogardus ST, Charpentier PA, Leo-Summers L, Acampora D, Holford TR, Cooney LM. A multicomponent intervention to prevent delirium in hospitalized older patients. New Engl J Med. 1999;340(9):669–76.CrossRefPubMed Inouye SK, Bogardus ST, Charpentier PA, Leo-Summers L, Acampora D, Holford TR, Cooney LM. A multicomponent intervention to prevent delirium in hospitalized older patients. New Engl J Med. 1999;340(9):669–76.CrossRefPubMed
2.
go back to reference Siddiqi N, Harrison J, Clegg A, Teale E, Young J, Taylor J, Simpkins S. Cochrane database of systematic reviews: interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev. 2016;3:CD005563.PubMed Siddiqi N, Harrison J, Clegg A, Teale E, Young J, Taylor J, Simpkins S. Cochrane database of systematic reviews: interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev. 2016;3:CD005563.PubMed
3.
go back to reference Ramirez-Bermudez J, Lopez-Gomez M, Ana LS, Aceves S, Nader-Kawachi J, Nicolini H. Frequency of delirium in a neurological emergency room. J Neuropsychiatry Clin Neurosc. 2006;18:108–12.CrossRef Ramirez-Bermudez J, Lopez-Gomez M, Ana LS, Aceves S, Nader-Kawachi J, Nicolini H. Frequency of delirium in a neurological emergency room. J Neuropsychiatry Clin Neurosc. 2006;18:108–12.CrossRef
4.
go back to reference Oldenbeuving AW, de Kort PLM, Jansen BPW, Algra A, Kappelle LJ, Roks G. Delirium in the acute phase after stroke incidence, risk factors, and outcome. Neurology. 2011;76:993–9.CrossRefPubMed Oldenbeuving AW, de Kort PLM, Jansen BPW, Algra A, Kappelle LJ, Roks G. Delirium in the acute phase after stroke incidence, risk factors, and outcome. Neurology. 2011;76:993–9.CrossRefPubMed
5.
go back to reference Ruiz Bajo B, Roche Bueno JC, Seral Moral M, Martin Martinez J. Incidence and predictive factors of delirium in hospitalised neurological patients. Neurologia. 2013;28(6):356–60.CrossRefPubMed Ruiz Bajo B, Roche Bueno JC, Seral Moral M, Martin Martinez J. Incidence and predictive factors of delirium in hospitalised neurological patients. Neurologia. 2013;28(6):356–60.CrossRefPubMed
6.
go back to reference Fong TG, Jones RN, Shi P, Marcantonio ER, Yap L, Rudolph JL, Yang FM, Kiely DK, Inouye SK. Delirium accelerates cognitive decline in Alzheimer disease. Neurology. 2009;72:1570–5.CrossRefPubMedPubMedCentral Fong TG, Jones RN, Shi P, Marcantonio ER, Yap L, Rudolph JL, Yang FM, Kiely DK, Inouye SK. Delirium accelerates cognitive decline in Alzheimer disease. Neurology. 2009;72:1570–5.CrossRefPubMedPubMedCentral
7.
go back to reference Martinez F, Tobar C, Hill N. Preventing delirium: should non-pharmacological, multicomponent interventions be used? A systematic review and meta-analysis of the literature. Age Ageing. 2015;44(2):196–204.CrossRefPubMed Martinez F, Tobar C, Hill N. Preventing delirium: should non-pharmacological, multicomponent interventions be used? A systematic review and meta-analysis of the literature. Age Ageing. 2015;44(2):196–204.CrossRefPubMed
8.
go back to reference Douglas VC, Hessler CS, Dhaliwal G, Betjemann JP, Fukuda KA, Alameddine LR, Lucatorto R, Johnston SC, Josephson SA. The AWOL tool: derivation and validation of a delirium prediction rule. J Hosp Med. 2013;8(9):493–9.CrossRefPubMed Douglas VC, Hessler CS, Dhaliwal G, Betjemann JP, Fukuda KA, Alameddine LR, Lucatorto R, Johnston SC, Josephson SA. The AWOL tool: derivation and validation of a delirium prediction rule. J Hosp Med. 2013;8(9):493–9.CrossRefPubMed
9.
go back to reference Brown EG, Josephson SA, Anderson N, Reid M, Lee M, Douglas VC. Predicting inpatient delirium: the AWOL delirium risk-stratification score in clinical practice. Geriatr Nurs. 2017; epub ahead of print Brown EG, Josephson SA, Anderson N, Reid M, Lee M, Douglas VC. Predicting inpatient delirium: the AWOL delirium risk-stratification score in clinical practice. Geriatr Nurs. 2017; epub ahead of print
10.
go back to reference Young J, Murthy L, Westby M, Akunne A, O'Mahony R. Diagnosis, prevention, and management of delirium: summary of NICE guidance. BMJ. 2010;341:c3704.CrossRefPubMed Young J, Murthy L, Westby M, Akunne A, O'Mahony R. Diagnosis, prevention, and management of delirium: summary of NICE guidance. BMJ. 2010;341:c3704.CrossRefPubMed
11.
go back to reference Inouye SK, Van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI. Clarifying confusion the confusion assessment method a new method for detection of delirium. Ann Int Med. 1990;113:941–8.CrossRefPubMed Inouye SK, Van Dyck CH, Alessi CA, Balkin S, Siegal AP, Horwitz RI. Clarifying confusion the confusion assessment method a new method for detection of delirium. Ann Int Med. 1990;113:941–8.CrossRefPubMed
12.
go back to reference Inouye SK, Leo-Summers L, Zhang Y, Bogardus ST, Leslie DL, Agostini JV. A chart-based method for identification of delirium: validation compared with interviewer ratings using the confusion assessment method. J Am Geriatr Soc. 2005;53:312–8.CrossRefPubMed Inouye SK, Leo-Summers L, Zhang Y, Bogardus ST, Leslie DL, Agostini JV. A chart-based method for identification of delirium: validation compared with interviewer ratings using the confusion assessment method. J Am Geriatr Soc. 2005;53:312–8.CrossRefPubMed
13.
go back to reference Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic Comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.CrossRefPubMed Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic Comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40(5):373–83.CrossRefPubMed
14.
go back to reference Witlox J, Eurelings LSM, Jonghe JFMD, Kalisvaart KJ, Eikelenboom P, van Gool WA. Delirium in elderly patients and the risk of Postdischarge mortality, institutionalization, and dementia. JAMA. 2010;304(4):443–51.CrossRefPubMed Witlox J, Eurelings LSM, Jonghe JFMD, Kalisvaart KJ, Eikelenboom P, van Gool WA. Delirium in elderly patients and the risk of Postdischarge mortality, institutionalization, and dementia. JAMA. 2010;304(4):443–51.CrossRefPubMed
15.
go back to reference StataCorp. Stata statistical software: release 13. College Station: StataCorp LP; 2013. StataCorp. Stata statistical software: release 13. College Station: StataCorp LP; 2013.
16.
go back to reference Kaboli PJ, Go JT, Hockenberry J, Glasgow JM, Johnson SR, Rosenthal GE, Jones MP, Vaughan-Sarrazin M. Associations between reduced hospital length of stay and 30-day readmission rate and mortality: 14-year experience in 129 veterans affairs hospitals. Ann Intern Med. 2012;157:837–45.CrossRefPubMed Kaboli PJ, Go JT, Hockenberry J, Glasgow JM, Johnson SR, Rosenthal GE, Jones MP, Vaughan-Sarrazin M. Associations between reduced hospital length of stay and 30-day readmission rate and mortality: 14-year experience in 129 veterans affairs hospitals. Ann Intern Med. 2012;157:837–45.CrossRefPubMed
17.
go back to reference Zaubler TS, Murphy K, Rizzuto L, Santos R, Skotzko C, Giordano J, Bustami R, Inouye SK. Quality improvement and cost savings with multicomponent delirium interventions: replication of the hospital elder life program in a community hospital. Psychosomatics. 2013;54:219–26.CrossRefPubMed Zaubler TS, Murphy K, Rizzuto L, Santos R, Skotzko C, Giordano J, Bustami R, Inouye SK. Quality improvement and cost savings with multicomponent delirium interventions: replication of the hospital elder life program in a community hospital. Psychosomatics. 2013;54:219–26.CrossRefPubMed
18.
go back to reference Weiss AJ, Elixhauser A. Overview of hospital stays in the United States, 2012. Rockville: Agency for Healthcare Research and Quality; 2014. Weiss AJ, Elixhauser A. Overview of hospital stays in the United States, 2012. Rockville: Agency for Healthcare Research and Quality; 2014.
19.
go back to reference Bakker FC, Persoon A, Bredie SJ, van Haren-Willems J, Leferink VJ, Noyez L, Schoon Y, Olde Rikkert MG. The CareWell in hospital program to improve the quality of care for frail elderly inpatients: results of a before-after study with focus on surgical patients. Am J Surg. 2014;208(5):735–46.CrossRefPubMed Bakker FC, Persoon A, Bredie SJ, van Haren-Willems J, Leferink VJ, Noyez L, Schoon Y, Olde Rikkert MG. The CareWell in hospital program to improve the quality of care for frail elderly inpatients: results of a before-after study with focus on surgical patients. Am J Surg. 2014;208(5):735–46.CrossRefPubMed
20.
go back to reference Chong MS, Chan M, Tay L, Ding YY. Outcomes of an innovative model of acute delirium care: the geriatric monitoring unit (GMU). Clin Interv Aging. 2014;9:603–12.CrossRefPubMedPubMedCentral Chong MS, Chan M, Tay L, Ding YY. Outcomes of an innovative model of acute delirium care: the geriatric monitoring unit (GMU). Clin Interv Aging. 2014;9:603–12.CrossRefPubMedPubMedCentral
21.
go back to reference Avendano-Cespedes A, Garcia-Cantos N, Gonzalez-Teruel MM, Martinez-Garcia M, Villarreal-Bocanegra E, Oliver-Carbonell JL, Abizanda P. Pilot study of a preventive multicomponent nurse intervention to reduce the incidence and severity of delirium in hospitalized older adults: MID-nurse-P. Maturitas. 2016;86:86–94.CrossRefPubMed Avendano-Cespedes A, Garcia-Cantos N, Gonzalez-Teruel MM, Martinez-Garcia M, Villarreal-Bocanegra E, Oliver-Carbonell JL, Abizanda P. Pilot study of a preventive multicomponent nurse intervention to reduce the incidence and severity of delirium in hospitalized older adults: MID-nurse-P. Maturitas. 2016;86:86–94.CrossRefPubMed
22.
go back to reference Vidan MT, Sanchez E, Alonso M, Montero B, Ortiz J, Serra JA. An intervention integrated into daily clinical practice reduces the incidence of delirium during hospitalization in elderly patients. J Am Geriatr Soc. 2009;57(11):2029–36.CrossRefPubMed Vidan MT, Sanchez E, Alonso M, Montero B, Ortiz J, Serra JA. An intervention integrated into daily clinical practice reduces the incidence of delirium during hospitalization in elderly patients. J Am Geriatr Soc. 2009;57(11):2029–36.CrossRefPubMed
23.
go back to reference Martinez FT, Tobar C, Beddings CI, Vallejo G, Fuentes P. Preventing delirium in an acute hospital using a non-pharmacological intervention. Age Ageing. 2012;41(5):629–34.CrossRefPubMed Martinez FT, Tobar C, Beddings CI, Vallejo G, Fuentes P. Preventing delirium in an acute hospital using a non-pharmacological intervention. Age Ageing. 2012;41(5):629–34.CrossRefPubMed
24.
go back to reference Kuhn E, Du X, McGrath K, Coveney S, O'Regan N, Richardson S, Teodorczuk A, Allan L, Wilson D, Inouye SK, et al. Validation of a consensus method for identifying delirium from hospital records. PLoS One. 2014;9(11):e111823.CrossRefPubMedPubMedCentral Kuhn E, Du X, McGrath K, Coveney S, O'Regan N, Richardson S, Teodorczuk A, Allan L, Wilson D, Inouye SK, et al. Validation of a consensus method for identifying delirium from hospital records. PLoS One. 2014;9(11):e111823.CrossRefPubMedPubMedCentral
25.
go back to reference Saczynski JS, Kosar CM, Xu G, Puelle MR, Schmitt E, Jones RN, Marcantonio ER, Wong B, Isaza I, Inouye SK. A tale of two methods: chart and interview methods for identifying delirium. J Am Geriatr Soc. 2014;62(3):518–24.CrossRefPubMedPubMedCentral Saczynski JS, Kosar CM, Xu G, Puelle MR, Schmitt E, Jones RN, Marcantonio ER, Wong B, Isaza I, Inouye SK. A tale of two methods: chart and interview methods for identifying delirium. J Am Geriatr Soc. 2014;62(3):518–24.CrossRefPubMedPubMedCentral
Metadata
Title
Evaluation of a multicomponent pathway to address inpatient delirium on a neurosciences ward
Authors
Ethan G. Brown
S. Andrew Josephson
Noriko Anderson
Mary Reid
Melissa Lee
Vanja C. Douglas
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2018
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/s12913-018-2906-3

Other articles of this Issue 1/2018

BMC Health Services Research 1/2018 Go to the issue