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BMC Women's Health
Published in: BMC Women's Health 1/2020

Open Access 01-12-2020 | Endometriosis | Research article

Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review

Authors: Julia L. Magnay, Shaughn O’Brien, Christoph Gerlinger, Christian Seitz

Published in: BMC Women's Health | Issue 1/2020

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Abstract

Background

Pictorial blood loss assessment charts (PBACs) represent the most widely used method to assess menstrual blood loss (MBL) in clinical trials. The aims of this review were to: (1) determine the diagnostic accuracy of PBACs that have been validated against the reference alkaline hematin technique; (2) categorize the pitfalls of using obsolete and nonvalidated charts; (3) provide guidelines for development of a new PBAC or use of an existing chart to measure MBL in clinical trials; and (4) consider the feasibility of using pictorial charts in primary care.

Methods

A literature review was conducted using Embase and MEDLINE databases. The review identified reports of women with self-perceived or actual heavy menstrual bleeding (HMB), bleeding disorders, abnormal uterine bleeding, leiomyomata (uterine fibroids) or endometriosis, and women undergoing treatment for HMB, as well as those with normal menstrual periods. Data were reviewed from studies that focused on the development and validation of PBACs and from those that used derivative noncertified charts to assess HMB.

Results

Nine studies reported validation of PBAC scoring systems against the alkaline hematin technique. Across these studies, the sensitivity was 58–97%, the specificity was 7.5–95.5%, the positive and negative likelihood ratios were 1.1–13.8 and 0.14–0.56, respectively, and the diagnostic odds ratio was 2.6–52.4. The cut-off score above which the diagnosis of HMB was made ranged from 50 to 185. Several modifications of these PBACs were used in other studies; however, objective confirmation of their validity was not reported. Overall, there was widespread inconsistency of chart design, scoring systems, diagnostic cut-off limits and post-treatment outcome measures.

Conclusions

PBACs are best suited to the controlled and specific environment of clinical studies, where clinical outcome parameters are defined. The current lack of standardization precludes widespread use of the PBAC in primary care.

Review registration number

PROSPERO international prospective register of systematic reviews: CRD42016030083.
Appendix
Available only for authorised users
Literature
1.
2.
Chimbira TH, Anderson AB, Turnbull A. Relation between measured menstrual blood loss and patient's subjective assessment of loss, duration of bleeding, number of sanitary towels used, uterine weight and endometrial surface area. Br J Obstet Gynaecol. 1980;87:603–9.PubMedCrossRef
3.
Gannon MJ, Day P, Hammadieh N, Johnson N. A new method for measuring menstrual blood loss and its use in screening women before endometrial ablation. Br J Obstet Gynaecol. 1996;103:1029–33.PubMedCrossRef
4.
Warner PE, Critchley HO, Lumsden MA, Campbell-Brown M, Douglas A, Murray GD. Menorrhagia I: measured blood loss, clinical features, and outcome in women with heavy periods: a survey with follow-up data. Am J Obstet Gynecol. 2004;190:1216–23.PubMedCrossRef
5.
Magnay JL, Nevatte TM, O'Brien S, Gerlinger C, Seitz C. Validation of a new menstrual pictogram (superabsorbent polymer-c version) for use with ultraslim towels that contain superabsorbent polymers. Fertil Steril. 2014;101:515–22.e5.PubMedCrossRef
6.
7.
Hallberg L, Hogdahl AM, Nilsson L, Rybo G. Menstrual blood loss--a population study. Variation at different ages and attempts to define normality. Acta Obstet Gynecol Scand. 1966;45:320–51.PubMedCrossRef
8.
Hallberg L, Nilsson L. Determination of menstrual blood loss. Scand J Clin Lab Invest. 1964;16:244–8.PubMedCrossRef
9.
van Eijkeren MA, Scholten PC, Christiaens GC, Alsbach GP, Haspels AA. The alkaline hematin method for measuring menstrual blood loss--a modification and its clinical use in menorrhagia. Eur J Obstet Gynecol Reprod Biol. 1986;22:345–51.PubMedCrossRef
10.
Vasilenko P, Kraicer PF, Kaplan R, de Masi A, Freed N. A new and simple method of measuring menstrual blood loss. J Reprod Med. 1988;33:293–7.PubMed
11.
Magnay JL, Nevatte TM, Dhingra V, O'Brien S. Menstrual blood loss measurement: validation of the alkaline hematin technique for feminine hygiene products containing superabsorbent polymers. Fertil Steril. 2010;94:2742–6.PubMedCrossRef
12.
Magnay JL, Schonicke G, Nevatte TM, O'Brien S, Junge W. Validation of a rapid alkaline hematin technique to measure menstrual blood loss on feminine towels containing superabsorbent polymers. Fertil Steril. 2011;96:394–8.PubMedCrossRef
13.
14.
Hoaglin DC, Filonenko A, Glickman ME, Wasiak R, Gidwani R. Use of mixed-treatment-comparison methods in estimating efficacy of treatments for heavy menstrual bleeding. Eur J Med Res. 2013;18:17.PubMedPubMedCentralCrossRef
15.
Abu Hashim H, Alsherbini W, Bazeed M. Contraceptive vaginal ring treatment of heavy menstrual bleeding: a randomized controlled trial with norethisterone. Contraception. 2012;85:246–52.PubMedCrossRef
16.
Chi C, Bapir M, Lee CA, Kadir RA. Puerperal loss (lochia) in women with or without inherited bleeding disorders. Am J Obstet Gynecol. 2010;203:56.ep1–5.CrossRef
17.
Dashtinejad E, Abedi P, Afshari P. Comparison of the effect of breast pump stimulation and oxytocin administration on the length of the third stage of labor, postpartum hemorrhage, and anemia: a randomized controlled trial. BMC Pregnancy Childbirth. 2018;18:293.PubMedPubMedCentralCrossRef
18.
Sherif N, Goubran H, Hassan A, Burnouf T, El-Ekiaby M. An approach to outreach patients with von Willebrand disease in Egypt by targeting women with heavy menstrual bleeding and/or bleeding symptoms. Haemophilia. 2014;20:238–43.PubMedCrossRef
19.
Gursel T, Biri A, Kaya Z, Sivaslioglu S, Albayrak M. The frequency of menorrhagia and bleeding disorders in university students. Pediatr Hematol Oncol. 2014;31:467–74.PubMedCrossRef
20.
Gupta S, Lemanczyk MA, Christopherson PA, Yan K, Hoffmann RG, Lund MR, et al. Cross sectional study to evaluate the utility of screening tools to identify low von Willebrand factor levels in women with menorrhagia (ZPMCB-VWD). Blood. 2010;116:3839.CrossRef
21.
Fernandez H, Kobelt G, Gervaise A. Economic evaluation of three surgical interventions for menorrhagia. Hum Reprod. 2003;18:583–7.PubMedCrossRef
22.
Famuyide AO, Laughlin-Tommaso SK, Shazly SA, Hall Long K, Breitkopf DM, Weaver AL, et al. Medical therapy versus radiofrequency endometrial ablation in the initial treatment of heavy menstrual bleeding (iTOM trial): a clinical and economic analysis. PLoS One. 2017;12:e0188176.PubMedPubMedCentralCrossRef
23.
Mohebbi-Kian E, Mohammad-Alizadeh-Charandabi S, Bekhradi R. Efficacy of fennel and combined oral contraceptive on depot medroxyprogesterone acetate-induced amenorrhea: a randomized placebo-controlled trial. Contraception. 2014;90:440–6.PubMedCrossRef
24.
25.
Fraser IS, McCarron G, Markham R, Resta T. Blood and total fluid content of menstrual discharge. Obstet Gynecol. 1985;65:194–8.PubMed
26.
Fraser IS, Warner P, Marantos PA. Estimating menstrual blood loss in women with normal and excessive menstrual fluid volume. Obstet Gynecol. 2001;98:806–14.PubMed
27.
Whiting PF, Weswood ME, Rutjes AW, Reitsma JB, Bossuyt PN, Kleijnen J. Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. BMC Med Res Methodol. 2006;6:9.PubMedPubMedCentralCrossRef
28.
Glas AS, Lijmer JG, Prins MH, Bonsel GJ, Bossuyt PM. The diagnostic odds ratio: a single indicator of test performance. J Clin Epidemiol. 2003;56:1129–35.PubMedCrossRef
29.
Higham JM, O'Brien PM, Shaw RW. Assessment of menstrual blood loss using a pictorial chart. Br J Obstet Gynaecol. 1990;97:734–9.PubMedCrossRef
30.
Deeny M, Davis JA. Assessment of menstrual blood loss in women referred for endometrial ablation. Eur J Obstet Gynecol Reprod Biol. 1994;57:179–80.PubMedCrossRef
31.
Janssen CA, Scholten PC, Heintz AP. A simple visual assessment technique to discriminate between menorrhagia and normal menstrual blood loss. Obstet Gynecol. 1995;85:977–82.PubMedCrossRef
32.
Barr F, Brabin L, Agbaje O. A pictorial chart for managing common menstrual disorders in Nigerian adolescents. Int J Gynaecol Obstet. 1999;66:51–3.PubMedCrossRef
33.
Reid PC, Coker A, Coltart R. Assessment of menstrual blood loss using a pictorial chart: a validation study. BJOG. 2000;107:320–2.PubMedCrossRef
34.
Wyatt KM, Dimmock PW, Walker TJ, O'Brien PM. Determination of total menstrual blood loss. Fertil Steril. 2001;76:125–31.PubMedCrossRef
35.
Zakherah MS, Sayed GH, El-Nashar SA, Shaaban MM. Pictorial blood loss assessment chart in the evaluation of heavy menstrual bleeding: diagnostic accuracy compared to alkaline hematin. Gynecol Obstet Investig. 2011;71:281–4.CrossRef
36.
Larsen L, Coyne K, Chwalisz K. Validation of the menstrual pictogram in women with leiomyomata associated with heavy menstrual bleeding. Reprod Sci. 2013;20:680–7.PubMedCrossRef
37.
Warrilow G, Kirkham C, Ismail KM, Wyatt K, Dimmock P, O'Brien S. Quantification of menstrual blood loss. Obstet Gynaecol. 2004;6:88–92.
38.
39.
40.
Reid PC. Assessment of menorrhagia by total menstrual fluid loss. J Obstet Gynaecol. 2006;26:438–41.PubMedCrossRef
41.
Lopes JE Jr, Sherer E. Managing menorrhagia. Evaluating and treating heavy menstrual bleeding. Adv NPs PAs. 2010;1:21–4 quiz 5.PubMed
42.
Kouides PA, Byams VR, Philipp CS, Stein SF, Heit JA, Lukes AS, et al. Multisite management study of menorrhagia with abnormal laboratory haemostasis: a prospective crossover study of intranasal desmopressin and oral tranexamic acid. Br J Haematol. 2009;145:212–20.PubMedCrossRef
43.
Mawet M, Nollevaux F, Nizet D, Wijzen F, Gordenne V, Tasev N, et al. Impact of a new levonorgestrel intrauterine system, Levosert((R)), on heavy menstrual bleeding: results of a one-year randomised controlled trial. Eur J Contracept Reprod Health Care. 2014;19:169–79.PubMedPubMedCentralCrossRef
44.
Goshtasebi A, Moukhah S, Gandevani SB. Treatment of heavy menstrual bleeding of endometrial origin: randomized controlled trial of medroxyprogesterone acetate and tranexamic acid. Arch Gynecol Obstet. 2013;288:1055–60.PubMedCrossRef
45.
46.
Bırı A, Bozkurt N, Korucuoğlu Ü, Yilmaz E, Tiraş B, Güner H. Use of pictorial chart for managing menorrhagia among Turkish women. J Turk Ger Gynecol Assoc. 2008;9:35–7.
47.
48.
Ahuja SP, Hertweck SP. Overview of bleeding disorders in adolescent females with menorrhagia. J Pediatr Adolesc Gynecol. 2010;23:S15–21.PubMedCrossRef
49.
Jacot-Guillarmod M, Renteria S. Troubles du cycle à l’adolescence : une banalité ? Rev Med Suisse. 2010;6:1236–41.PubMed
50.
Lee CA, Kadir RA, Kouides PA. Pictorial blood loss assessment chart. Inherited bleeding disorders in women. Hoboken: Blackwell Publishing Ltd; 2009. Appendix ii 186–7CrossRef
51.
52.
53.
Waldvogel S, Pedrazzini B, Vaucher P, Bize R, Cornuz J, Tissot J-D, et al. Clinical evaluation of iron treatment efficiency among non-anemic but iron-deficient female blood donors: a randomized controlled trial. BMC Med. 2012;10:8.PubMedPubMedCentralCrossRef
54.
Donnez J, Hudecek R, Donnez O, Matule D, Arhendt HJ, Zatik J, et al. Efficacy and safety of repeated use of ulipristal acetate in uterine fibroids. Fertil Steril. 2015;103:519–27.e3.PubMedCrossRef
55.
Nahidi F, Bagheri L, Jannesari S, Alavi MH. Relationship between delivery type and menstrual disorders: a case-control study. J Res Health Sci. 2011;11:83–90.PubMed
56.
Hald K, Lieng M. Assessment of periodic blood loss: interindividual and intraindividual variations of pictorial blood loss assessment chart registrations. J Minim Invasive Gynecol. 2014;21:662–8.PubMedCrossRef
57.
Dasharathy SS, Mumford SL, Pollack AZ, Perkins NJ, Mattison DR, Wactawski-Wende J, et al. Menstrual bleeding patterns among regularly menstruating women. Am J Epidemiol. 2012;175:536–45.PubMedPubMedCentralCrossRef
58.
Laberge P, Garza-Leal J, Fortin C, Sabbah R, Fulop T, Pasztor N, et al. One-year follow-up results of a multicenter, single-arm, objective performance criteria-controlled international clinical study of the safety and efficacy of the Minerva endometrial ablation system. J Minim Invasive Gynecol. 2015;22:1169–77.PubMedCrossRef
59.
Brölmann H, Bongers M, Garza-Leal JG, Gupta J, Veersema S, Quartero R, et al. The FAST-EU trial: 12-month clinical outcomes of women after intrauterine sonography-guided transcervical radiofrequency ablation of uterine fibroids. Gynecol Surg. 2016;13:27–35.PubMedCrossRef
60.
Ashraf MN, Habib-Ur-Rehman A, Shehzad Z, AlSharari SD, Murtaza G. Clinical efficacy of levonorgestrel and norethisterone for the treatment of chronic abnormal uterine bleeding. J Pak Med Assoc. 2017;67:1331–8.PubMed
61.
Hacioglu S, Karabulut A, Sari I, Keskin A. Haemostatic disorders in reproductive age women with menorrhagia and effects on quality of life. J Obstet Gynaecol. 2016;36:1041–5.PubMedCrossRef
62.
Barrington JW, Bowen-Simpkins P. The levonorgestrel intrauterine system in the management of menorrhagia. Br J Obstet Gynaecol. 1997;104:614–6.PubMedCrossRef
63.
Kashefi F, Khajehei M, Alavinia M, Golmakani E, Asili J. Effect of ginger (Zingiber officinale) on heavy menstrual bleeding: a placebo-controlled, randomized clinical trial. Phytother Res. 2015;29:114–9.PubMedCrossRef
64.
Gorgen H, Api M, Akca A, Cetin A. Use of the Levonorgestrel-IUS in the treatment of menorrhagia: assessment of quality of life in Turkish users. Arch Gynecol Obstet. 2009;279:835–40.PubMedCrossRef
65.
Herman MC, Mol BW, Bongers MY. Diagnosis of heavy menstrual bleeding. Womens Health (Lond). 2016;12:15–20.CrossRef
66.
67.
Kilic C, Sarper N, Zengin E, Aylan Gelen S. Screening bleeding disorders in adolescents and young women with menorrhagia. Turk J Haematol. 2013;30:168–76.CrossRef
68.
Cash C Jr, Garza-Leal J, Donovan A, Guidry C, Romanowski C, Patel B. Clinical evaluation of long-term safety and effectiveness of a third-generation thermal uterine balloon therapy system for heavy menstrual bleeding. J Minim Invasive Gynecol. 2012;19:469–76.PubMedCrossRef
69.
Gopimohan R, Chandran A, Jacob J, Bhaskar S, Aravindhakshan R, Aprem AS. A clinical study assessing the efficacy of a new variant of the levonorgestrel intrauterine system for abnormal uterine bleeding. Int J Gynaecol Obstet. 2015;129:114–7.PubMedCrossRef
70.
Puri K, Famuyide AO, Erwin PJ, Stewart EA, Laughlin-Tommaso SK. Submucosal fibroids and the relation to heavy menstrual bleeding and anemia. Am J Obstet Gynecol. 2014;210:38.e1–7.CrossRef
71.
Han JY, Lee EJ, Jee BC, Kim SH. Menstrual characteristics in Korean women with endometriosis: a pilot study. Obstet Gynecol Sci. 2018;61:142–6.PubMedCrossRef
72.
van Dongen H, Janssen CA, Smeets MJ, Emanuel MH, Jansen FW. The clinical relevance of hysteroscopic polypectomy in premenopausal women with abnormal uterine bleeding. BJOG. 2009;116:1387–90.PubMedCrossRef
73.
Knol HM, Mulder AB, Bogchelman DH, Kluin-Nelemans HC, van der Zee AG, Meijer K. The prevalence of underlying bleeding disorders in patients with heavy menstrual bleeding with and without gynecologic abnormalities. Am J Obstet Gynecol. 2013;209:202.e1–7.CrossRef
74.
Philipp CS, Faiz A, Dowling NF, Beckman M, Owens S, Ayers C, et al. Development of a screening tool for identifying women with menorrhagia for hemostatic evaluation. Am J Obstet Gynecol. 2008;198:163.e1–8.CrossRef
75.
76.
Grimes DA. Estimating vaginal blood loss. J Reprod Med. 1979;22:190–2.PubMed
77.
Treetampinich C, Suwannarurk K, Chanthasenanont A, Fongsupa S, Tamrongterakul T, Rattanachaiyanont M. Blood absorption capacity of various sanitary pads available in Thailand. Siriraj. Med J. 2017;59:303–6.
78.
Nevatte TM, Borlase D, Magnay JL, O'Brien S. Evaluation of the menstrual pictogram and detergent based alkaline haematin method for use with ultra slim sanitary towels. BJOG. 2008;115:191.
79.
Corson SL, Brill AI, Brooks PG, Cooper JM, Indman PD, Liu JH, et al. One-year results of the vesta system for endometrial ablation. J Am Assoc Gynecol Laparosc. 2000;7:489–97.PubMedCrossRef
80.
Lin X, Gao ES, Li D, Zhang M, Dou LX, Yuan W. Preventive treatment of intrauterine device-induced menstrual blood loss with tranexamic acid in Chinese women. Acta Obstet Gynecol Scand. 2007;86:1126–9.PubMedCrossRef
81.
Khadige A, Keshavarz Z, Mojab F, Majd HA. The effect of Teucrium polium on the duration of menstrual bleeding: a triple-blind placebo-controlled clinical trial. Electron Physician. 2017;9:5233–6.PubMedPubMedCentralCrossRef
82.
Qaraaty M, Kamali SH, Dabaghian FH, Zafarghandi N, Mokaberinejad R, Mobli M, et al. Effect of myrtle fruit syrup on abnormal uterine bleeding: a randomized double-blind, placebo-controlled pilot study. Daru. 2014;22:45.PubMedPubMedCentralCrossRef
83.
Mun S, Uysal A. The effects of hysteroscopic submucosal myoma resection on number of sanitary pads. J Clin Anal Med. 2015;6:75–8.CrossRef
84.
Leeflang MM, Rutjes AW, Reitsma JB, Hooft L, Bossuyt PM. Variation of a test’s sensitivity and specificity with disease prevalence. CMAJ. 2013;185:E537–44.PubMedPubMedCentralCrossRef
85.
Woeller KE, Hochwalt AE. Safety assessment of sanitary pads with a polymeric foam absorbent core. Regul Toxicol Pharmacol. 2015;73:419–24.PubMedCrossRef
86.
Magnay JL, Nevatte TM, Seitz C, O'Brien S. A new menstrual pictogram for use with feminine products that contain superabsorbent polymers. Fertil Steril. 2013;100:1715.e1–21.e4.CrossRef
87.
88.
89.
Prashanthi GC, Popuri PK, Valluri P. Efficacy of tranexamic acid in the management of menorrhagia. Acta Biomed Sci. 2016;3:116–20.
90.
Johannes CB, Crawford SL, Woods J, Goldstein RB, Tran D, Mehrotra S, et al. An electronic menstrual cycle calendar: comparison of data quality with a paper version. Menopause. 2000;7:200–8.PubMedCrossRef
91.
Wyatt KM, Dimmock PW, Hayes-Gill B, Crowe J, O'Brien PM. Menstrual symptometrics: a simple computer-aided method to quantify menstrual cycle disorders. Fertil Steril. 2002;78:96–101.PubMedCrossRef
92.
Jacobson AE, Vesely SK, Haamid F, Christian-Rancy M, O'Brien SH. Mobile application vs paper pictorial blood assessment chart to track menses in young women: a randomized cross-over design. J Pediatr Adolesc Gynecol. 2018;31:84–8.PubMedCrossRef
93.
MacEachern K, Kaur H, Toukh M, Mumal I, Hamilton A, Scovil S, et al. Comprehensive evaluation of hemostasis in normal women: impact on the diagnosis of mild bleeding disorders. Clin Appl Thromb Hemost. 2015;21:72–81.PubMedCrossRef
94.
Deal LS, Williams VS, Fehnel SE. Development of an electronic daily uterine fibroid symptom diary. Patient. 2011;4:31–44.PubMedCrossRef
95.
Agarwal N, Gupta M, Kriplani A, Bhatla N, Singh N. Comparison of combined hormonal vaginal ring with ultralow-dose combined oral contraceptive pills in the management of heavy menstrual bleeding: a pilot study. J Obstet Gynaecol. 2016;36:71–5.PubMedCrossRef
96.
Shaw RW, Symonds IM, Tamizian O, Chaplain J, Mukhopadhyay S. Randomised comparative trial of thermal balloon ablation and levonorgestrel intrauterine system in patients with idiopathic menorrhagia. Aust N Z J Obstet Gynaecol. 2007;47:335–40.PubMedCrossRef
97.
Farquhar C, Brown J. Oral contraceptive pill for heavy menstrual bleeding. Cochrane Database Syst Rev. 2009:Cd000154.
98.
Kiseli M, Kayikcioglu F, Evliyaoglu O, Haberal A. Comparison of therapeutic efficacies of norethisterone, tranexamic acid and levonorgestrel-releasing intrauterine system for the treatment of heavy menstrual bleeding: a randomized controlled study. Gynecol Obstet Investig. 2016;81:447–53.CrossRef
99.
Hald K, Klow NE, Qvigstad E, Istre O. Laparoscopic occlusion compared with embolization of uterine vessels: a randomized controlled trial. Obstet Gynecol. 2007;109:20–7.PubMedCrossRef
100.
Lukes AS, Muse K, Richter HE, Moore KA, Patrick DL. Estimating a meaningful reduction in menstrual blood loss for women with heavy menstrual bleeding. Curr Med Res Opin. 2010;26:2673–8.PubMedCrossRef
101.
Warner P, Weir CJ, Hansen CH, Douglas A, Madhra M, Hillier SG, et al. Low-dose dexamethasone as a treatment for women with heavy menstrual bleeding: protocol for response-adaptive randomised placebo-controlled dose-finding parallel group trial (DexFEM). BMJ Open. 2015;5.PubMedPubMedCentralCrossRef
102.
Ragni MV, Jankowitz RC, Jaworski K, Merricks EP, Kloos MT, Nichols TC. Phase II prospective open-label trial of recombinant interleukin-11 in women with mild von Willebrand disease and refractory menorrhagia. Thromb Haemost. 2011;106:641–5.PubMedPubMedCentralCrossRef
103.
Soper DE, Winkel C, Larsen L, Fries M, Lee R, Chwalisz K. Validation of the menstrual pictogram compared with the AH method to assess menstrual blood loss. Obstet Gynecol Sci. 2007;109(Suppl22S).
104.
Bongers M, Brolmann H, Gupta J, Garza-Leal JG, Toub D. Transcervical, intrauterine ultrasound-guided radiofrequency ablation of uterine fibroids with the VizAblate(R) system: three- and six-month endpoint results from the FAST-EU study. Gynecol Surg. 2015;12:61–70.PubMedCrossRef
105.
Liu M, Cheng Z, Dai H, Qu X, Kang L. Long-term efficacy and quality of life associated with laparoscopic bilateral uterine artery occlusion plus partial resection of symptomatic adenomyosis. Eur J Obstet Gynecol Reprod Biol. 2014;176:20–4.PubMedCrossRef
106.
Herman MC, Mak N, Geomini PM, Winkens B, Mol BW, Bongers MY. Is the pictorial blood loss assessment chart (PBAC) score associated with treatment outcome after endometrial ablation for heavy menstrual bleeding? A cohort study. BJOG. 2017;124:277–82.PubMedCrossRef
107.
Chi C, Huq FY, Kadir RA. Levonorgestrel-releasing intrauterine system for the management of heavy menstrual bleeding in women with inherited bleeding disorders: long-term follow-up. Contraception. 2011;83:242–7.PubMedCrossRef
108.
Seitz C, Bumbuliene Z, Costa AR, Heikinheimo O, Heweker A, Hudecek R, et al. Rationale and design of ASTEROID 2, a randomized, placebo- and active comparator-controlled study to assess the efficacy and safety of vilaprisan in patients with uterine fibroids. Contemp Clin Trials. 2017;55:56–62.PubMedCrossRef
109.
Huq FY, Al-Haderi M, Kadir RA. The outcome of endometrial ablation in women with inherited bleeding disorders. Haemophilia. 2012;18:413–20.PubMedCrossRef
110.
Arora D, Chawla J, Kochar SPS, Sharma JC. A randomized control trial to assess efficacy of mifepristone in medical management of uterine fibroid. Med J Armed Forces India. 2017;73:267–73.PubMedPubMedCentralCrossRef
111.
Kriplani A, Srivastava A, Kulshrestha V, Kachhawa G, Agarwal N, Bhatla N, et al. Efficacy of ormeloxifene versus oral contraceptive in the management of abnormal uterine bleeding due to uterine leiomyoma. J Obstet Gynaecol Res. 2016;42:1744–52.PubMedCrossRef
112.
Kapur A, Angomchanu R, Dey M. Efficacy of use of long-term, low-dose mifepristone for the treatment of fibroids. J Obstet Gynaecol India. 2016;66:494–8.PubMedPubMedCentralCrossRef
113.
Vercellini P, Oldani S, De Giorgi O, Milesi M, Merlo D, Crosignani PG. Endometrial ablation with a vaporizing electrode. II. Clinical outcome of a pilot study. Acta Obstet Gynecol Scand. 1998;77:688–93.PubMedCrossRef
114.
Endrikat J, Vilos G, Muysers C, Fortier M, Solomayer E, Lukkari-Lax E. The levonorgestrel-releasing intrauterine system provides a reliable, long-term treatment option for women with idiopathic menorrhagia. Arch Gynecol Obstet. 2012;285:117–21.PubMedCrossRef
115.
Rees MCP. Role of menstrual blood loss measurements in management of complaints of excessive menstrual bleeding. BJOG. 1991;98:327–8.CrossRef
116.
Higham J, Reid P. A preliminary investigation of what happens to women complaining of menorrhagia but whose complaint is not substantiated. J Psychosom Obstet Gynaecol. 1995;16:211–4.PubMedCrossRef
117.
Halimeh S. Menorrhagia and bleeding disorders in adolescent females. Hamostaseologie. 2012;32:45–50.PubMedCrossRef
118.
Philipp CS, Faiz A, Heit JA, Kouides PA, Lukes A, Stein SF, et al. Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia. Am J Obstet Gynecol. 2011;204:209.e1–e2097.CrossRef
119.
Shapley M, Redman CWE. Assessment of menstrual blood loss using a pictorial chart and endometrial sampling within the community. J Obstet Gynaecol. 1995;15:123–4.CrossRef
Metadata
Title
Pictorial methods to assess heavy menstrual bleeding in research and clinical practice: a systematic literature review
Authors
Julia L. Magnay
Shaughn O’Brien
Christoph Gerlinger
Christian Seitz
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Endometriosis
Published in
BMC Women's Health / Issue 1/2020
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-020-0887-y

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Do future healthcare professionals have adequate knowledge about risk factors for stress urinary incontinence in women?