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Published in: BMC Urology 1/2023

Open Access 01-12-2023 | Stress Incontinence | Research

Comparison of the short-term efficacy and safety of bipolar transurethral electro vaporization and holmium laser enucleation of the prostate for moderate and large benign prostatic enlargement

Authors: Yutaro Hayashi, Shuko Yoneyama, Akitoshi Takizawa, Kazuki Kobayashi, Hiroki Ito

Published in: BMC Urology | Issue 1/2023

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Abstract

Background

To compare the efficacy and safety of bipolar transurethral vaporization of the prostate (B-TUVP) with holmium laser enucleation of the prostate (HoLEP) for moderate [prostate volume (PV) 30–80 ml] and large (≥ 80 ml) benign prostatic enlargement (BPE).

Materials and methods

Male patients with lower urinary tract symptom (LUTS) or urinary retention who underwent B-TUVP or HoLEP treatment in two regional centers were respectively enrolled. Patient characteristics and treatment outcomes were retrospectively compared between B-TUVP and HoLEP.

Results

In patients with moderate and large prostate volume,B-TUVP showed shorter operative time (P < 0.001) and less hemoglobin decrease (P < 0.001) than in HoLEP. In uncatheterised patients, voiding symptoms and patients’ quality of life improved after B-TUVP and HoLEP, but these improvement rates were consistently bigger in HoLEP than in B-TUVP. In catheterised patients, the rate of achieving catheter-free status after surgery was higher in HoLEP than in B-TUVP for patients with PV > 80 ml.(P < 0.001) The incidence of postoperative fever was higher in B-TUVP than in HoLEP for patients with PV 30–80 ml (P < 0.001) but not for those with PV > 80 ml.(P=0.08) The Incidence of postoperative stress incontinence(SUI) was higher in HoLEP than in B-TUVP for patients with moderate and large prostate volume.

Conclusions

There are few studies that investigated the short-term efficacy and safety of second-generation B-TUVP in comparison with HoLEP for moderate and large BPE. Improvement in LUTS and achievement of catheter-free status were predominant in HoLEP, and these outcomes were more prominent in patients with large BPE of PV > 80 ml. However, B-TUVP resulted in less blood loss, shorter operative duration, and less SUI suggesting that B-TUVP is also well-tolerated surgical modality.
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Literature
2.
go back to reference Parsons JK, Dahm P, Kohler TS, Lerner LB, Wilt TJ. Surgical Management of Lower urinary tract symptoms attributed to Benign Prostatic Hyperplasia: AUA Guideline Amendment 2020. J Urol. 2020;204:799–804.CrossRefPubMed Parsons JK, Dahm P, Kohler TS, Lerner LB, Wilt TJ. Surgical Management of Lower urinary tract symptoms attributed to Benign Prostatic Hyperplasia: AUA Guideline Amendment 2020. J Urol. 2020;204:799–804.CrossRefPubMed
3.
go back to reference Kaya C, Ilktac A, Gokmen E, Ozturk M, Karaman IM. The long-term results of transurethral vaporization of the prostate using plasmakinetic energy. BJU Int. 2007;99:845–8.CrossRefPubMed Kaya C, Ilktac A, Gokmen E, Ozturk M, Karaman IM. The long-term results of transurethral vaporization of the prostate using plasmakinetic energy. BJU Int. 2007;99:845–8.CrossRefPubMed
4.
go back to reference Elsakka AM, Eltatawy HH, Almekaty KH, et al. A prospective randomised controlled study comparing bipolar plasma vaporisation of the prostate to monopolar transurethral resection of the prostate. Arab J Urol. 2016;14:280–6.CrossRefPubMedPubMedCentral Elsakka AM, Eltatawy HH, Almekaty KH, et al. A prospective randomised controlled study comparing bipolar plasma vaporisation of the prostate to monopolar transurethral resection of the prostate. Arab J Urol. 2016;14:280–6.CrossRefPubMedPubMedCentral
5.
go back to reference Fukazawa T, Ito H, Takanashi M, et al. Short-term efficacy and safety of second generation bipolar transurethral vaporization of the prostate (B-TUVP) for large benign prostate enlargement: results from a retrospective feasibility study. PLoS ONE. 2021;16:e0261586.CrossRefPubMedPubMedCentral Fukazawa T, Ito H, Takanashi M, et al. Short-term efficacy and safety of second generation bipolar transurethral vaporization of the prostate (B-TUVP) for large benign prostate enlargement: results from a retrospective feasibility study. PLoS ONE. 2021;16:e0261586.CrossRefPubMedPubMedCentral
6.
go back to reference Uehara K, Ito H, Takanashi M et al. Retrospective analysis of second-generation bipolar transurethral vaporization of the prostate in older patients aged ≥ 80 years with benign prostate enlargement. Continence 2022; 2. Uehara K, Ito H, Takanashi M et al. Retrospective analysis of second-generation bipolar transurethral vaporization of the prostate in older patients aged ≥ 80 years with benign prostate enlargement. Continence 2022; 2.
7.
go back to reference Kim KS, Lee SH, Cho HJ et al. Comparison of Bipolar Plasma Vaporization versus Standard Holmium Laser Enucleation of the Prostate: Surgical Procedures and Clinical Outcomes for Small Prostate Volumes. J Clin Med 2019;8. Kim KS, Lee SH, Cho HJ et al. Comparison of Bipolar Plasma Vaporization versus Standard Holmium Laser Enucleation of the Prostate: Surgical Procedures and Clinical Outcomes for Small Prostate Volumes. J Clin Med 2019;8.
8.
go back to reference Yip SK, Chan NH, Chiu P, Lee KW, Ng CF. A randomized controlled trial comparing the efficacy of hybrid bipolar transurethral vaporization and resection of the prostate with bipolar transurethral resection of the prostate. J Endourol. 2011;25:1889–94.CrossRefPubMed Yip SK, Chan NH, Chiu P, Lee KW, Ng CF. A randomized controlled trial comparing the efficacy of hybrid bipolar transurethral vaporization and resection of the prostate with bipolar transurethral resection of the prostate. J Endourol. 2011;25:1889–94.CrossRefPubMed
9.
go back to reference Zhang SY, Hu H, Zhang XP, et al. Efficacy and safety of bipolar plasma vaporization of the prostate with “button-type” electrode compared with transurethral resection of prostate for benign prostatic hyperplasia. Chin Med J (Engl). 2012;125:3811–4.PubMed Zhang SY, Hu H, Zhang XP, et al. Efficacy and safety of bipolar plasma vaporization of the prostate with “button-type” electrode compared with transurethral resection of prostate for benign prostatic hyperplasia. Chin Med J (Engl). 2012;125:3811–4.PubMed
10.
go back to reference Geavlete B, Multescu R, Dragutescu M, et al. Transurethral resection (TUR) in saline plasma vaporization of the prostate vs standard TUR of the prostate: ‘the better choice’ in benign prostatic hyperplasia? BJU Int. 2010;106:1695–9.CrossRefPubMed Geavlete B, Multescu R, Dragutescu M, et al. Transurethral resection (TUR) in saline plasma vaporization of the prostate vs standard TUR of the prostate: ‘the better choice’ in benign prostatic hyperplasia? BJU Int. 2010;106:1695–9.CrossRefPubMed
11.
go back to reference Robert G, de la Taille A, Herrmann T. Bipolar plasma vaporization of the prostate: ready to replace GreenLight? A systematic review of randomized control trials. World J Urol. 2015;33:549–54.CrossRefPubMed Robert G, de la Taille A, Herrmann T. Bipolar plasma vaporization of the prostate: ready to replace GreenLight? A systematic review of randomized control trials. World J Urol. 2015;33:549–54.CrossRefPubMed
12.
go back to reference Ghobrial FK, Shoma A, Elshal AM, et al. A randomized trial comparing bipolar transurethral vaporization of the prostate with GreenLight laser (xps-180watt) photoselective vaporization of the prostate for treatment of small to moderate benign prostatic obstruction: outcomes after 2 years. BJU Int. 2020;125:144–52.CrossRefPubMed Ghobrial FK, Shoma A, Elshal AM, et al. A randomized trial comparing bipolar transurethral vaporization of the prostate with GreenLight laser (xps-180watt) photoselective vaporization of the prostate for treatment of small to moderate benign prostatic obstruction: outcomes after 2 years. BJU Int. 2020;125:144–52.CrossRefPubMed
13.
go back to reference Cornu JN, Ahyai S, Bachmann A, et al. A systematic review and Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from Benign Prostatic obstruction: an update. Eur Urol. 2015;67:1066–96.CrossRefPubMed Cornu JN, Ahyai S, Bachmann A, et al. A systematic review and Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from Benign Prostatic obstruction: an update. Eur Urol. 2015;67:1066–96.CrossRefPubMed
14.
go back to reference Habib E, Ayman LM, ElSheemy MS, et al. Holmium Laser Enucleation vs Bipolar Plasmakinetic Enucleation of a large volume Benign Prostatic Hyperplasia: a Randomized Controlled Trial. J Endourol. 2020;34:330–8.CrossRefPubMed Habib E, Ayman LM, ElSheemy MS, et al. Holmium Laser Enucleation vs Bipolar Plasmakinetic Enucleation of a large volume Benign Prostatic Hyperplasia: a Randomized Controlled Trial. J Endourol. 2020;34:330–8.CrossRefPubMed
15.
go back to reference Habib EI, ElSheemy MS, Hossam A, et al. Holmium Laser Enucleation Versus Bipolar Plasmakinetic Resection for Management of Lower urinary tract symptoms in patients with large-volume Benign Prostatic Hyperplasia: randomized-controlled trial. J Endourol. 2021;35:171–9.CrossRefPubMed Habib EI, ElSheemy MS, Hossam A, et al. Holmium Laser Enucleation Versus Bipolar Plasmakinetic Resection for Management of Lower urinary tract symptoms in patients with large-volume Benign Prostatic Hyperplasia: randomized-controlled trial. J Endourol. 2021;35:171–9.CrossRefPubMed
16.
go back to reference Bozzini G, Berti L, Aydogan TB, et al. A prospective multicenter randomized comparison between Holmium Laser Enucleation of the prostate (HoLEP) and Thulium Laser Enucleation of the prostate (ThuLEP). World J Urol. 2021;39:2375–82.CrossRefPubMed Bozzini G, Berti L, Aydogan TB, et al. A prospective multicenter randomized comparison between Holmium Laser Enucleation of the prostate (HoLEP) and Thulium Laser Enucleation of the prostate (ThuLEP). World J Urol. 2021;39:2375–82.CrossRefPubMed
17.
go back to reference Naspro R, Suardi N, Salonia A, et al. Holmium laser enucleation of the prostate versus open prostatectomy for prostates > 70 g: 24-month follow-up. Eur Urol. 2006;50:563–8.CrossRefPubMed Naspro R, Suardi N, Salonia A, et al. Holmium laser enucleation of the prostate versus open prostatectomy for prostates > 70 g: 24-month follow-up. Eur Urol. 2006;50:563–8.CrossRefPubMed
18.
go back to reference Ahyai SA, Lehrich K, Kuntz RM. Holmium laser enucleation versus transurethral resection of the prostate: 3-year follow-up results of a randomized clinical trial. Eur Urol. 2007;52:1456–63.CrossRefPubMed Ahyai SA, Lehrich K, Kuntz RM. Holmium laser enucleation versus transurethral resection of the prostate: 3-year follow-up results of a randomized clinical trial. Eur Urol. 2007;52:1456–63.CrossRefPubMed
19.
go back to reference Kuntz RM, Lehrich K, Ahyai SA. Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial. Eur Urol. 2008;53:160–6.CrossRefPubMed Kuntz RM, Lehrich K, Ahyai SA. Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial. Eur Urol. 2008;53:160–6.CrossRefPubMed
20.
go back to reference Zhong J, Feng Z, Peng Y, Liang H. Review and Meta-analysis of Efficacy and Safety following Holmium laser enucleation of prostate and transurethral resection of prostate for Benign Prostatic Hyperplasia. Urology. 2019;131:14–20.CrossRefPubMed Zhong J, Feng Z, Peng Y, Liang H. Review and Meta-analysis of Efficacy and Safety following Holmium laser enucleation of prostate and transurethral resection of prostate for Benign Prostatic Hyperplasia. Urology. 2019;131:14–20.CrossRefPubMed
21.
go back to reference Cornu JN, Bipolar M. Photovaporization of the prostate, or Holmium Laser Enucleation of the prostate: how to choose what’s best? Urol Clin North Am. 2016;43:377–84.CrossRefPubMed Cornu JN, Bipolar M. Photovaporization of the prostate, or Holmium Laser Enucleation of the prostate: how to choose what’s best? Urol Clin North Am. 2016;43:377–84.CrossRefPubMed
22.
go back to reference Robert G, Cornu JN, Fourmarier M, et al. Multicentre prospective evaluation of the learning curve of holmium laser enucleation of the prostate (HoLEP). BJU Int. 2016;117:495–9.CrossRefPubMed Robert G, Cornu JN, Fourmarier M, et al. Multicentre prospective evaluation of the learning curve of holmium laser enucleation of the prostate (HoLEP). BJU Int. 2016;117:495–9.CrossRefPubMed
23.
go back to reference Das AK, Teplitsky S, Chandrasekar T, et al. Stress urinary incontinence post-Holmium Laser Enucleation of the prostate: a single-surgeon experience. Int Braz J Urol. 2020;46:624–31.CrossRefPubMedPubMedCentral Das AK, Teplitsky S, Chandrasekar T, et al. Stress urinary incontinence post-Holmium Laser Enucleation of the prostate: a single-surgeon experience. Int Braz J Urol. 2020;46:624–31.CrossRefPubMedPubMedCentral
24.
go back to reference Cho MC, Park JH, Jeong MS, et al. Predictor of de novo urinary incontinence following holmium laser enucleation of the prostate. Neurourol Urodyn. 2011;30:1343–9.PubMed Cho MC, Park JH, Jeong MS, et al. Predictor of de novo urinary incontinence following holmium laser enucleation of the prostate. Neurourol Urodyn. 2011;30:1343–9.PubMed
25.
go back to reference Shah HN, Mahajan AP, Hegde SS, Bansal MB. Peri-operative complications of holmium laser enucleation of the prostate: experience in the first 280 patients, and a review of literature. BJU Int. 2007;100:94–101.CrossRefPubMed Shah HN, Mahajan AP, Hegde SS, Bansal MB. Peri-operative complications of holmium laser enucleation of the prostate: experience in the first 280 patients, and a review of literature. BJU Int. 2007;100:94–101.CrossRefPubMed
26.
go back to reference Seki N, Mochida O, Kinukawa N, Sagiyama K, Naito S. Holmium laser enucleation for prostatic adenoma: analysis of learning curve over the course of 70 consecutive cases. J Urol. 2003;170:1847–50.CrossRefPubMed Seki N, Mochida O, Kinukawa N, Sagiyama K, Naito S. Holmium laser enucleation for prostatic adenoma: analysis of learning curve over the course of 70 consecutive cases. J Urol. 2003;170:1847–50.CrossRefPubMed
27.
go back to reference Ibrahim A, Alharbi M, Elhilali MM, Aube M, Carrier S. 18 years of Holmium Laser Enucleation of the prostate: a single Center experience. J Urol. 2019;202:795–800.CrossRefPubMed Ibrahim A, Alharbi M, Elhilali MM, Aube M, Carrier S. 18 years of Holmium Laser Enucleation of the prostate: a single Center experience. J Urol. 2019;202:795–800.CrossRefPubMed
Metadata
Title
Comparison of the short-term efficacy and safety of bipolar transurethral electro vaporization and holmium laser enucleation of the prostate for moderate and large benign prostatic enlargement
Authors
Yutaro Hayashi
Shuko Yoneyama
Akitoshi Takizawa
Kazuki Kobayashi
Hiroki Ito
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Urology / Issue 1/2023
Electronic ISSN: 1471-2490
DOI
https://doi.org/10.1186/s12894-023-01215-8

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