Published in:
Open Access
01-12-2017 | Case report
Chronic recurrent multifocal osteomyelitis beginning with a solitary lesion of the ilium
Authors:
Ping Zhang, Xiao Ying Jia, Yun Zhang, John Morelli, Ze Kun Zhang
Published in:
BMC Musculoskeletal Disorders
|
Issue 1/2017
Login to get access
Abstract
Background
Chronic recurrent multifocal osteomyelitis (CRMO) is an idiopathic inflammatory disease. The initial lesions are typically found in the metaphyses, generally without periosteal reaction.
Case presentation
We present a case of a 14-year-old female teenager with relapsing and remitting right iliac pain. There was no evidence of infectious organisms, neoplastic processes, or hematologic malignancy based on laboratory tests. Initial computed tomography (CT) and magnetic resonance imaging (MRI) demonstrated atypical periosteal proliferation in the right ilium. Histopathology demonstrated only non-specific chronic inflammation compatible with CRMO. Two years later, this patient developed left humeral pain. MRI and CT images revealed thickening and marrow edema involving the humeral cortex.
Conclusions
This case highlights that CRMO can begin as a unifocal lesion and also possibly within the ilium, despite usually being multifocal and involving the long bone metaphysis.