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Open Access 01-12-2016 | Research article

Associations between body composition measurements of obesity and radiographic osteoarthritis in older adults: Data from the Dong-gu Study

Authors: Lihui Wen, Ji-Hyoun Kang, Yi-Rang Yim, Ji-Eun Kim, Jeong-Won Lee, Kyung-Eun Lee, Dong-Jin Park, Tae-Jong Kim, Yong-Wook Park, Sun-Seog Kweon, Young-Hoon Lee, Yong-Woon Yun, Min-Ho Shin, Shin-Seok Lee

Published in: BMC Musculoskeletal Disorders | Issue 1/2016

Abstract

Background

We examined the effects of fat deposition on radiographic osteoarthritis (OA) to determine the role of obesity in the pathogenesis of radiographic OA.

Methods

Data were taken from the Dong-gu cohort, a cross-sectional study of 2,367 subjects. Baseline characteristics, waist circumference (WC), waist-to-hip ratio (WHR), fat mass, and fat percentage were collected, along with X-rays of the knees and hands. Total knee and hand radiographic OA scores were summed using a semi-quantitative grading system, and then stratified by gender using a multiple linear regression model.

Results

After adjusting for confounders, weight was the only factor significantly associated with knee radiographic OA, regardless of gender (all p < 0.01). Regarding the hand, fat percentage had the largest effect on radiographic OA in males (p = 0.008), while WHR was the most significant factor in females (p = 0.001). For the knee, fat mass was the most important factor for radiographic OA in males (p = 0.001), while in females, body mass index was the most important factor (p < 0.001). Among the variables, only fat percentage was significantly related to both hand and knee radiographic OA in both genders (all p < 0.01).

Conclusions

Regardless of gender, weight was significantly associated with knee radiographic OA. Otherwise, fat deposition correlated with hand and knee radiographic OA in both genders, while the distribution of fat tissue was significantly associated with hand and knee radiographic OA only in females.

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Title: Associations between body composition measurements of obesity and radiographic osteoarthritis in older adults: Data from the Dong-gu Study
Authors: Lihui Wen
Ji-Hyoun Kang
Yi-Rang Yim
Ji-Eun Kim
Jeong-Won Lee
Kyung-Eun Lee
Dong-Jin Park
Tae-Jong Kim
Yong-Wook Park
Sun-Seog Kweon
Young-Hoon Lee
Yong-Woon Yun
Min-Ho Shin
Shin-Seok Lee
Publication date: 01-12-2016
Publisher: BioMed Central
Published in: BMC Musculoskeletal Disorders / Issue 1/2016
Electronic ISSN: 1471-2474
DOI: https://doi.org/10.1186/s12891-016-1040-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Associations between body composition measurements of obesity and radiographic osteoarthritis in older adults: Data from the Dong-gu Study

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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