Skip to main content
Top
Published in: BMC Public Health 1/2015

Open Access 01-12-2015 | Research article

Awareness and low uptake of post exposure prophylaxis for HIV among clinical medical students in a high endemicity setting

Authors: Leopold Ndemnge Aminde, Noah F. Takah, Jean Jacques N. Noubiap, Maxime Tindong, Calypse Ngwasiri, Ahmadou M. Jingi, Andre Pascal Kengne, Anastase Dzudie

Published in: BMC Public Health | Issue 1/2015

Login to get access

Abstract

Background

Adequate knowledge and practices on post exposure prophylaxis (PEP) for HIV among health care providers are crucial for HIV prevention. However there is limited data on PEP knowledge and practice from developing countries where the burden of HIV infection continues to increase. We assessed the knowledge of clinical medical students on PEP, their practices in response to occupational exposure to HIV, as well as the determinants of good knowledge on PEP.

Methods

A cross-sectional study was conducted in November 2014 involving 154 consecutively recruited clinical medical students (4th-6th year undergraduates). Data were acquired using a structured questionnaire. Knowledge on PEP was assessed using a questionnaire comprising 25 questions and categorized as: good (20 or more correct answers), moderate (13–19 correct answers) and poor (12 or fewer correct answers).

Results

For the 154 students included (57.8 % being male), the mean age was 23.2 ± 2.4 years, and 89 % had heard about PEP for HIV. The majority of students had moderate (61.7 %) and poor (32.5 %) knowledge on PEP. Overall knowledge score increased with increasing level of studies (p < 0.05). Only 10 (6.5 %) had had previous training on PEP, most of whom were senior level students (p = 0.01). Fifty-four students (35.1 %) knew the appropriate duration of PEP and this awareness increased with level of studies (p = 0.001). Of the 81 (52.6 %) who reported occupational exposure to HIV in the past, only 4 (4.9 %) received PEP.

Conclusions

Overall, knowledge on PEP among clinical medical students in this setting was non-optimal with very low uptake PEP. Intensification of HIV curricula to involve PEP as well as continuous medical education programs and workshops are potential avenues to improve awareness in this vulnerable population.
Literature
2.
go back to reference Baytner-Zamir R, Lorber M, Hermoni D. Assessment of the knowledge and attitudes regarding HIV/AIDS among pre-clinical medical students in Israel. BMC Res Notes. 2014;7(1):168.CrossRefPubMedPubMedCentral Baytner-Zamir R, Lorber M, Hermoni D. Assessment of the knowledge and attitudes regarding HIV/AIDS among pre-clinical medical students in Israel. BMC Res Notes. 2014;7(1):168.CrossRefPubMedPubMedCentral
5.
go back to reference Sultan B, Benn P, Waters L. Current perspectives in HIV post-exposure prophylaxis. HIVAIDS Auckl NZ. 2014;6:147–58. Sultan B, Benn P, Waters L. Current perspectives in HIV post-exposure prophylaxis. HIVAIDS Auckl NZ. 2014;6:147–58.
6.
go back to reference Pinto LA, Landay AL, Berzofsky JA, Kessler HA, Shearer GM. Immune response to human immunodeficiency virus (HIV) in healthcare workers occupationally exposed to HIV-contaminated blood. Am J Med. 1997;102(5B):21–4.CrossRefPubMed Pinto LA, Landay AL, Berzofsky JA, Kessler HA, Shearer GM. Immune response to human immunodeficiency virus (HIV) in healthcare workers occupationally exposed to HIV-contaminated blood. Am J Med. 1997;102(5B):21–4.CrossRefPubMed
7.
go back to reference Spira AI, Marx PA, Patterson BK, Mahoney J, Koup RA, Wolinsky SM, et al. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J Exp Med. 1996;183(1):215–25.CrossRefPubMed Spira AI, Marx PA, Patterson BK, Mahoney J, Koup RA, Wolinsky SM, et al. Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J Exp Med. 1996;183(1):215–25.CrossRefPubMed
8.
9.
go back to reference Otten RA, Smith DK, Adams DR, Pullium JK, Jackson E, Kim CN, et al. Efficacy of postexposure prophylaxis after intravaginal exposure of Pig-tailed macaques to a human-derived retrovirus (human immunodeficiency virus type 2). J Virol. 2000;74(20):9771–5.CrossRefPubMedPubMedCentral Otten RA, Smith DK, Adams DR, Pullium JK, Jackson E, Kim CN, et al. Efficacy of postexposure prophylaxis after intravaginal exposure of Pig-tailed macaques to a human-derived retrovirus (human immunodeficiency virus type 2). J Virol. 2000;74(20):9771–5.CrossRefPubMedPubMedCentral
10.
go back to reference Cardo DM, Culver DH, Ciesielski CA, Srivastava PU, Marcus R, Abiteboul D, et al. A case–control study of HIV seroconversion in health care workers after percutaneous exposure. N Engl J Med. 1997;337(21):1485–90.CrossRefPubMed Cardo DM, Culver DH, Ciesielski CA, Srivastava PU, Marcus R, Abiteboul D, et al. A case–control study of HIV seroconversion in health care workers after percutaneous exposure. N Engl J Med. 1997;337(21):1485–90.CrossRefPubMed
11.
go back to reference Mathewos B, Birhan W, Kinfe S, Boru M, Tiruneh G, Addis Z, et al. Assessment of knowledge, attitude and practice towards post exposure prophylaxis for HIV among health care workers in Gondar, North West Ethiopia. BMC Public Health. 2013;13(1):508.CrossRefPubMedPubMedCentral Mathewos B, Birhan W, Kinfe S, Boru M, Tiruneh G, Addis Z, et al. Assessment of knowledge, attitude and practice towards post exposure prophylaxis for HIV among health care workers in Gondar, North West Ethiopia. BMC Public Health. 2013;13(1):508.CrossRefPubMedPubMedCentral
12.
go back to reference Owolabi RS, Alabi P, Ajayi S, Daniel O, Ogundiran A, Akande TM, et al. Knowledge and practice of post-exposure prophylaxis (PEP) against HIV infection among health care providers in a tertiary hospital in Nigeria. J Int Assoc Physicians AIDS Care Chic Ill 2002. 2012;11(3):179–83.CrossRef Owolabi RS, Alabi P, Ajayi S, Daniel O, Ogundiran A, Akande TM, et al. Knowledge and practice of post-exposure prophylaxis (PEP) against HIV infection among health care providers in a tertiary hospital in Nigeria. J Int Assoc Physicians AIDS Care Chic Ill 2002. 2012;11(3):179–83.CrossRef
13.
go back to reference Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, et al. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis. Infect Control Hosp Epidemiol. 2013;34(9):875–92.CrossRefPubMed Kuhar DT, Henderson DK, Struble KA, Heneine W, Thomas V, Cheever LW, et al. Updated US Public Health Service guidelines for the management of occupational exposures to human immunodeficiency virus and recommendations for postexposure prophylaxis. Infect Control Hosp Epidemiol. 2013;34(9):875–92.CrossRefPubMed
14.
go back to reference Tebeje B, Hailu C. Assessment of HIV post-exposure prophylaxis Use among health workers of governmental health institutions in jimma zone, oromiya region, Southwest Ethiopia. Ethiop J Health Sci. 2010;20(1):55–64.PubMedPubMedCentral Tebeje B, Hailu C. Assessment of HIV post-exposure prophylaxis Use among health workers of governmental health institutions in jimma zone, oromiya region, Southwest Ethiopia. Ethiop J Health Sci. 2010;20(1):55–64.PubMedPubMedCentral
15.
go back to reference Ajibola S, Akinbami A, Elikwu C, Odesanya M, Uche E. Knowledge, attitude and practices of HIV post exposure prophylaxis amongst health workers in Lagos University Teaching Hospital. Pan Afr Med J. 2014;19:172 Ajibola S, Akinbami A, Elikwu C, Odesanya M, Uche E. Knowledge, attitude and practices of HIV post exposure prophylaxis amongst health workers in Lagos University Teaching Hospital. Pan Afr Med J. 2014;19:172
16.
go back to reference Lamichanne J, Aryal B, Dhakal KS. Knowledge of nurses on post exposure prophylaxis of HIV in medical colleges of chitwan district, Nepal. Int J Pharm Biolog Arch. 2012;3(6):1394–9. Lamichanne J, Aryal B, Dhakal KS. Knowledge of nurses on post exposure prophylaxis of HIV in medical colleges of chitwan district, Nepal. Int J Pharm Biolog Arch. 2012;3(6):1394–9.
17.
go back to reference Aminde LN, Takah NF, Dzudie A, Bonko NM, Awungafac G, Teno D, et al. Occupational Post-Exposure Prophylaxis (PEP) against Human Immunodeficiency Virus (HIV) infection in a health district in Cameroon: assessment of the knowledge and practices of nurses. PLoS One. 2015;10(4):e0124416.CrossRefPubMedPubMedCentral Aminde LN, Takah NF, Dzudie A, Bonko NM, Awungafac G, Teno D, et al. Occupational Post-Exposure Prophylaxis (PEP) against Human Immunodeficiency Virus (HIV) infection in a health district in Cameroon: assessment of the knowledge and practices of nurses. PLoS One. 2015;10(4):e0124416.CrossRefPubMedPubMedCentral
18.
go back to reference Esin IA, Alabi S, Ojo E, Ajape AA. Knowledge of human immunodeficiency virus post-exposure prophylaxis among doctors in a Nigerian tertiary hospital. Niger J Clin Pract. 2011;14(4):464–6.CrossRefPubMed Esin IA, Alabi S, Ojo E, Ajape AA. Knowledge of human immunodeficiency virus post-exposure prophylaxis among doctors in a Nigerian tertiary hospital. Niger J Clin Pract. 2011;14(4):464–6.CrossRefPubMed
19.
go back to reference Agaba PA, Agaba EI, Ocheke AN, Daniyam CA, Akanbi MO, Okeke EN. Awareness and knowledge of human immunodeficiency virus post exposure prophylaxis among Nigerian family physicians. Niger Med J J Niger Med Assoc. 2012;53(3):155–60.CrossRef Agaba PA, Agaba EI, Ocheke AN, Daniyam CA, Akanbi MO, Okeke EN. Awareness and knowledge of human immunodeficiency virus post exposure prophylaxis among Nigerian family physicians. Niger Med J J Niger Med Assoc. 2012;53(3):155–60.CrossRef
20.
go back to reference Nwanko TO, Aniebue UU. Percutaneous injuries and accidental blood exposure in surgical residents: Awareness and use of prophylaxis in relation to HIV. Niger J Clin Pract. 2011;14:34–7.CrossRef Nwanko TO, Aniebue UU. Percutaneous injuries and accidental blood exposure in surgical residents: Awareness and use of prophylaxis in relation to HIV. Niger J Clin Pract. 2011;14:34–7.CrossRef
21.
go back to reference Sendo EG. Assessment of level of knowledge and practice of nursing and midwifery students on HIV post exposure prophylaxis in hawassa university Ethiopia. J HIV Clin Sci Res. 2014;1:101. Sendo EG. Assessment of level of knowledge and practice of nursing and midwifery students on HIV post exposure prophylaxis in hawassa university Ethiopia. J HIV Clin Sci Res. 2014;1:101.
22.
go back to reference Chacko J, Isaac R. Percutaneous injuries among medical interns and their knowledge and practice of post exposure prophylaxis for HIV. Indian J Public Health. 2007;51:127–9.PubMed Chacko J, Isaac R. Percutaneous injuries among medical interns and their knowledge and practice of post exposure prophylaxis for HIV. Indian J Public Health. 2007;51:127–9.PubMed
23.
go back to reference Kasat V, Saluja H, Ladda R, Sachdeva S, Somasundaram K, Gupta A. Knowledge, attitude and practices toward post exposure prophylaxis for human immunodeficiency virus among dental students in India. Ann Med Health Sci Res. 2014;4(4):543–8.CrossRefPubMedPubMedCentral Kasat V, Saluja H, Ladda R, Sachdeva S, Somasundaram K, Gupta A. Knowledge, attitude and practices toward post exposure prophylaxis for human immunodeficiency virus among dental students in India. Ann Med Health Sci Res. 2014;4(4):543–8.CrossRefPubMedPubMedCentral
24.
go back to reference Mesfin YM, Kibret KT. Assessment of knowledge and practice towards hepatitis B among medical and health science students in Haramaya University. Ethiopia PloS One. 2013;8(11):e79642.CrossRefPubMed Mesfin YM, Kibret KT. Assessment of knowledge and practice towards hepatitis B among medical and health science students in Haramaya University. Ethiopia PloS One. 2013;8(11):e79642.CrossRefPubMed
26.
go back to reference Gupta A, Anand S, Sastry J, Krisagar A, Basavaraj A, Bhat SM, et al. High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune. India BMC Infect Dis. 2008;8(1):142.CrossRefPubMed Gupta A, Anand S, Sastry J, Krisagar A, Basavaraj A, Bhat SM, et al. High risk for occupational exposure to HIV and utilization of post-exposure prophylaxis in a teaching hospital in Pune. India BMC Infect Dis. 2008;8(1):142.CrossRefPubMed
27.
go back to reference Ahmed SI, Hassali MA, Aziz NA. An assessment of the knowledge, attitudes, and risk perceptions of pharmacy students regarding HIV/AIDS. Am J Pharm Educ. 2009;73(1):15.CrossRefPubMedPubMedCentral Ahmed SI, Hassali MA, Aziz NA. An assessment of the knowledge, attitudes, and risk perceptions of pharmacy students regarding HIV/AIDS. Am J Pharm Educ. 2009;73(1):15.CrossRefPubMedPubMedCentral
28.
go back to reference Ryalat ST, Sawair FA, Shayyab MH, Amin WM. The knowledge and attitude about HIV/AIDS among Jordanian dental students: (Clinical versus pre clinical students) at the University of Jordan. BMC Res Notes. 2011;4:191.CrossRefPubMedPubMedCentral Ryalat ST, Sawair FA, Shayyab MH, Amin WM. The knowledge and attitude about HIV/AIDS among Jordanian dental students: (Clinical versus pre clinical students) at the University of Jordan. BMC Res Notes. 2011;4:191.CrossRefPubMedPubMedCentral
29.
go back to reference Chogle NL, Chogle MN, Divatia JV, Dasgupta D. Awareness of post exposure prophylaxis guidelines against occupational exposure to HIV in Mumbai hospital. Natl Med J India. 2002;5(2):69–72. Chogle NL, Chogle MN, Divatia JV, Dasgupta D. Awareness of post exposure prophylaxis guidelines against occupational exposure to HIV in Mumbai hospital. Natl Med J India. 2002;5(2):69–72.
30.
go back to reference Irvine C, Egan KJ, Shubber Z, Van Rompay KKA, Beanland RL, Ford N. Efficacy of HIV postexposure prophylaxis: systematic review and meta-analysis of nonhuman primate studies. Clin Infect Dis Off Publ Infect Dis Soc Am. 2015;60 Suppl 3:S165–9.CrossRef Irvine C, Egan KJ, Shubber Z, Van Rompay KKA, Beanland RL, Ford N. Efficacy of HIV postexposure prophylaxis: systematic review and meta-analysis of nonhuman primate studies. Clin Infect Dis Off Publ Infect Dis Soc Am. 2015;60 Suppl 3:S165–9.CrossRef
31.
go back to reference Bairy KL, Ganaraja B, Indira B, Thiyagar N, Choo CM, See CK. Awareness of post-exposure prophylaxis guidelines against occupational exposure to HIV in Hospital Sungai Petani. Med J Malaysia. 2005;60(1):10–4.PubMed Bairy KL, Ganaraja B, Indira B, Thiyagar N, Choo CM, See CK. Awareness of post-exposure prophylaxis guidelines against occupational exposure to HIV in Hospital Sungai Petani. Med J Malaysia. 2005;60(1):10–4.PubMed
32.
go back to reference Bandolier E. Occupational exposure to hospital employees in Italian hospitals over 5.5 years. London: AstraZeneca group; 2003. Bandolier E. Occupational exposure to hospital employees in Italian hospitals over 5.5 years. London: AstraZeneca group; 2003.
33.
go back to reference Tetali S, Choudhury PL. Occupational exposure to sharps and splash: Risk among health care providers in three tertiary care hospitals in south India. Indian J Occup Environ Med. 2006;10(1):35–40.CrossRef Tetali S, Choudhury PL. Occupational exposure to sharps and splash: Risk among health care providers in three tertiary care hospitals in south India. Indian J Occup Environ Med. 2006;10(1):35–40.CrossRef
34.
go back to reference Bhattarai S, K C S, Pradhan PMS, Lama S, Rijal S. Hepatitis B vaccination status and Needle-stick and Sharps-related Injuries among medical school students in Nepal: a cross-sectional study. BMC Res Notes. 2014;7:774.CrossRefPubMedPubMedCentral Bhattarai S, K C S, Pradhan PMS, Lama S, Rijal S. Hepatitis B vaccination status and Needle-stick and Sharps-related Injuries among medical school students in Nepal: a cross-sectional study. BMC Res Notes. 2014;7:774.CrossRefPubMedPubMedCentral
35.
36.
go back to reference Abrahams N, Jewkes R. Barriers to post exposure prophylaxis (PEP) completion after rape: a South African qualitative study. Cult Health Sex. 2010;12(5):471–84.CrossRefPubMed Abrahams N, Jewkes R. Barriers to post exposure prophylaxis (PEP) completion after rape: a South African qualitative study. Cult Health Sex. 2010;12(5):471–84.CrossRefPubMed
Metadata
Title
Awareness and low uptake of post exposure prophylaxis for HIV among clinical medical students in a high endemicity setting
Authors
Leopold Ndemnge Aminde
Noah F. Takah
Jean Jacques N. Noubiap
Maxime Tindong
Calypse Ngwasiri
Ahmadou M. Jingi
Andre Pascal Kengne
Anastase Dzudie
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2015
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-015-2468-9

Other articles of this Issue 1/2015

BMC Public Health 1/2015 Go to the issue