Skip to main content
Top
Published in: BMC Psychiatry 1/2017

Open Access 01-12-2017 | Research article

Pain severity predicts depressive symptoms over and above individual illnesses and multimorbidity in older adults

Authors: Louise Sharpe, Sarah McDonald, Helen Correia, Patrick J. Raue, Tanya Meade, Michael Nicholas, Patricia Arean

Published in: BMC Psychiatry | Issue 1/2017

Login to get access

Abstract

Background

Multi-morbidity in older adults is commonly associated with depressed mood. Similarly, subjective reports of pain are also associated with both physical illness and increased depressive symptoms. However, whether pain independently contributes to the experience of depression in older people with multi-morbidity has not been studied.

Methods

In this study, participants were 1281 consecutive older adults presenting to one of 19 primary care services in Australia (recruitment rate = 75%). Participants were asked to indicate the presence of a number of common chronic illnesses, to rate their current pain severity and to complete the Geriatric Depression Scale.

Results

Results confirmed that the number of medical illnesses reported was strongly associated with depressive symptoms. Twenty-six percent of participants with multi-morbidity scored in the clinical range for depressive symptoms in comparison to 15% of participants with no illnesses or a single illness. In regression analyses, the presence of chronic pain (t = 5.969, p < 0.0005), diabetes (t = 4.309, p < 0.0005), respiratory (t = 3.720, p < 0.0005) or neurological illness (t = 2.701, p = 0.007) were all independent contributors to depressive symptoms. Even when controlling for each individual illness, and the overall number of illnesses (t = 2.207, p = 0.028), pain severity remained an independent predictor of depressed mood (F change = 28.866, p < 0.0005, t = 5.373, p < 0.0005).

Conclusions

Physicians should consider screening for mood problems amongst those with multi-morbidity, particularly those who experience pain.
Literature
1.
go back to reference Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B. Epidemiology of multimorbidity and implications for health care, research, and medical education: A cross-sectional study. Lancet. 2012;380(9836):37–43.CrossRefPubMed Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B. Epidemiology of multimorbidity and implications for health care, research, and medical education: A cross-sectional study. Lancet. 2012;380(9836):37–43.CrossRefPubMed
2.
go back to reference Gunn JM, Ayton DR, Densley K, Pallant JF, Chondros P, Herrman HE, Dowrick CF. The association between chronic illness, multimorbidity and depressive symptoms in an Australian primary care cohort. Soc Psychiatry Psychiatr Epidemiol. 2012;47(2):175–84.CrossRefPubMed Gunn JM, Ayton DR, Densley K, Pallant JF, Chondros P, Herrman HE, Dowrick CF. The association between chronic illness, multimorbidity and depressive symptoms in an Australian primary care cohort. Soc Psychiatry Psychiatr Epidemiol. 2012;47(2):175–84.CrossRefPubMed
3.
go back to reference Britt H, Harrison C, Miller G, Knox S. Prevalence and patterns of multimorbidity in Australia. Med J Aust. 2008;189:72–7.PubMed Britt H, Harrison C, Miller G, Knox S. Prevalence and patterns of multimorbidity in Australia. Med J Aust. 2008;189:72–7.PubMed
5.
go back to reference Wong SY, Mercer SW, Woo J, Leung J. The influence of multi-morbidity and self-reported socio-economic standing on the prevalence of depression in an elderly Hong Kong population. BMC Public Health. 2008;8(1):119.CrossRefPubMedPubMedCentral Wong SY, Mercer SW, Woo J, Leung J. The influence of multi-morbidity and self-reported socio-economic standing on the prevalence of depression in an elderly Hong Kong population. BMC Public Health. 2008;8(1):119.CrossRefPubMedPubMedCentral
6.
go back to reference Lee Y, Choi K, Lee YK. Association of comorbidity with depressive symptoms in community-dwelling older persons. Gerontology. 2001;47(5):254–62.CrossRefPubMed Lee Y, Choi K, Lee YK. Association of comorbidity with depressive symptoms in community-dwelling older persons. Gerontology. 2001;47(5):254–62.CrossRefPubMed
7.
go back to reference Gallegos-Carrillo K, García-Peña C, Mudgal J, Romero X, Durán-Arenas L, Salmerón J. Role of depressive symptoms and comorbid chronic disease on health-related quality of life among community-dwelling older adults. J Psychosom Res. 2009;66(2):127–35.CrossRefPubMed Gallegos-Carrillo K, García-Peña C, Mudgal J, Romero X, Durán-Arenas L, Salmerón J. Role of depressive symptoms and comorbid chronic disease on health-related quality of life among community-dwelling older adults. J Psychosom Res. 2009;66(2):127–35.CrossRefPubMed
8.
go back to reference Jang Y, Shin J, Cho S, Kim G, Chiriboga DA. The interactive role of chronic medical conditions and sleep disturbance in predicting depressive symptoms among Korean American older adults. Aging Ment Health. 2011;15(2):198–203.CrossRefPubMed Jang Y, Shin J, Cho S, Kim G, Chiriboga DA. The interactive role of chronic medical conditions and sleep disturbance in predicting depressive symptoms among Korean American older adults. Aging Ment Health. 2011;15(2):198–203.CrossRefPubMed
9.
go back to reference Pfaff JJ, Draper BM, Pirkis JE, Stocks NP, Snowdon JA, Sim MG, Byrne GJ, Lautenschlager NT, Flicker LA, Kerse NM. Medical morbidity and severity of depression in a large primary care sample of older Australians: The DEPS-GP project. Med J Aust. 2009;190(7):S75.PubMed Pfaff JJ, Draper BM, Pirkis JE, Stocks NP, Snowdon JA, Sim MG, Byrne GJ, Lautenschlager NT, Flicker LA, Kerse NM. Medical morbidity and severity of depression in a large primary care sample of older Australians: The DEPS-GP project. Med J Aust. 2009;190(7):S75.PubMed
10.
go back to reference Egede LE. Major depression in individuals with chronic medical disorders: Prevalence, correlates and association with health resource utilization, lost productivity and functional disability. Gen Hosp Psychiatry. 2007;29(5):409–16.CrossRefPubMed Egede LE. Major depression in individuals with chronic medical disorders: Prevalence, correlates and association with health resource utilization, lost productivity and functional disability. Gen Hosp Psychiatry. 2007;29(5):409–16.CrossRefPubMed
11.
go back to reference Moussavi S, Chatterji S, Verdes E, Tandon A, Patel V, Ustun B. Depression, chronic diseases, and decrements in health: Results from the World Health Surveys. Lancet. 2007;370(9590):851–8.CrossRefPubMed Moussavi S, Chatterji S, Verdes E, Tandon A, Patel V, Ustun B. Depression, chronic diseases, and decrements in health: Results from the World Health Surveys. Lancet. 2007;370(9590):851–8.CrossRefPubMed
12.
go back to reference Patel KV, Guralnik JM, Dansie EJ, Turk DC. Prevalence and impact of pain among older adults in the United States: Findings from the 2011 National Health and Aging Trends Study. Pain. 2013;154(12):2649–57.CrossRefPubMed Patel KV, Guralnik JM, Dansie EJ, Turk DC. Prevalence and impact of pain among older adults in the United States: Findings from the 2011 National Health and Aging Trends Study. Pain. 2013;154(12):2649–57.CrossRefPubMed
13.
go back to reference Butchart A, Kerr EA, Heisler M, Piette JD, Krein SL. Experience and management of chronic pain among patients with other complex chronic conditions. Clin J Pain. 2009;25(4):293.CrossRefPubMedPubMedCentral Butchart A, Kerr EA, Heisler M, Piette JD, Krein SL. Experience and management of chronic pain among patients with other complex chronic conditions. Clin J Pain. 2009;25(4):293.CrossRefPubMedPubMedCentral
14.
go back to reference Meyer T, Cooper J, Raspe H. Disabling low back pain and depressive symptoms in the community-dwelling elderly: A prospective study. Spine. 2007;32(21):2380–6.CrossRefPubMed Meyer T, Cooper J, Raspe H. Disabling low back pain and depressive symptoms in the community-dwelling elderly: A prospective study. Spine. 2007;32(21):2380–6.CrossRefPubMed
15.
go back to reference Ohayon MM, Schatzberg AF. Chronic pain and major depressive disorder in the general population. J Psychiatr Res. 2010;44(7):454–61.CrossRefPubMed Ohayon MM, Schatzberg AF. Chronic pain and major depressive disorder in the general population. J Psychiatr Res. 2010;44(7):454–61.CrossRefPubMed
16.
go back to reference Tooth L, Hockey R, Byles J, Dobson A. Weighted multimorbidity indexes predicted mortality, health service use, and health-related quality of life in older women. J Clin Epidemiol. 2008;61(2):151–9.CrossRefPubMed Tooth L, Hockey R, Byles J, Dobson A. Weighted multimorbidity indexes predicted mortality, health service use, and health-related quality of life in older women. J Clin Epidemiol. 2008;61(2):151–9.CrossRefPubMed
17.
go back to reference Kempen GI, Jelicic M, Ormel J. Personality, chronic medical morbidity, and health-related quality of life among older persons. Health Psychol. 1997;16(6):539.CrossRefPubMed Kempen GI, Jelicic M, Ormel J. Personality, chronic medical morbidity, and health-related quality of life among older persons. Health Psychol. 1997;16(6):539.CrossRefPubMed
18.
go back to reference Hunger M, Thorand B, Schunk M, Döring A, Menn P, Peters A, Holle R. Multimorbidity and health-related quality of life in the older population: results from the German KORA-Age study. Health Qual Life Outcomes. 2011;9(1):1.CrossRef Hunger M, Thorand B, Schunk M, Döring A, Menn P, Peters A, Holle R. Multimorbidity and health-related quality of life in the older population: results from the German KORA-Age study. Health Qual Life Outcomes. 2011;9(1):1.CrossRef
19.
go back to reference Matcham F, Rayner L, Steer S, Hotopf M. The prevalence of depression in rheumatoid arthritis: A systematic review and meta-analysis. Rheumatology (Oxford). 2013;52(12):2136–48.CrossRef Matcham F, Rayner L, Steer S, Hotopf M. The prevalence of depression in rheumatoid arthritis: A systematic review and meta-analysis. Rheumatology (Oxford). 2013;52(12):2136–48.CrossRef
20.
go back to reference Aguglia A, Salvi V, Maina G, Rossetto I, Aguglia E. Fibromyalgia syndrome and depressive symptoms: comorbidity and clinical correlates. J Affect Disord. 2011;128(3):262–6.CrossRefPubMed Aguglia A, Salvi V, Maina G, Rossetto I, Aguglia E. Fibromyalgia syndrome and depressive symptoms: comorbidity and clinical correlates. J Affect Disord. 2011;128(3):262–6.CrossRefPubMed
21.
go back to reference Mayer TG, Towns BL, Neblett R, Theodore BR, Gatchel RJ. Chronic widespread pain in patients with occupational spinal disorders: Prevalence, psychiatric comorbidity, and association with outcomes. Spine. 2008;33(17):1889–97.CrossRefPubMed Mayer TG, Towns BL, Neblett R, Theodore BR, Gatchel RJ. Chronic widespread pain in patients with occupational spinal disorders: Prevalence, psychiatric comorbidity, and association with outcomes. Spine. 2008;33(17):1889–97.CrossRefPubMed
22.
go back to reference O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: Systematic review and proposed classification. Pain. 2008;137(1):96–111.CrossRefPubMed O’Connor AB, Schwid SR, Herrmann DN, Markman JD, Dworkin RH. Pain associated with multiple sclerosis: Systematic review and proposed classification. Pain. 2008;137(1):96–111.CrossRefPubMed
23.
go back to reference Laird BJ, Boyd AC, Colvin LA, Fallon MT. Are cancer pain and depression interdependent? A systematic review. Psycho-Oncology. 2009;18(5):459–64.CrossRefPubMed Laird BJ, Boyd AC, Colvin LA, Fallon MT. Are cancer pain and depression interdependent? A systematic review. Psycho-Oncology. 2009;18(5):459–64.CrossRefPubMed
24.
go back to reference Wolfe F, Michaud K. Predicting depression in rheumatoid arthritis: The signal importance of pain extent and fatigue, and comorbidity. Arthritis Care Res. 2009;61(5):667–73.CrossRef Wolfe F, Michaud K. Predicting depression in rheumatoid arthritis: The signal importance of pain extent and fatigue, and comorbidity. Arthritis Care Res. 2009;61(5):667–73.CrossRef
25.
go back to reference Sharpe L, Gittins CB, Correia HM, Meade T, Nicholas MK, Raue PJ, McDonald S, Areán PA. Problem-solving versus cognitive restructuring of medically ill seniors with depression (PROMISE-D trial): Study protocol and design. BMC Psychiatry. 2012;12(1):207.CrossRefPubMedPubMedCentral Sharpe L, Gittins CB, Correia HM, Meade T, Nicholas MK, Raue PJ, McDonald S, Areán PA. Problem-solving versus cognitive restructuring of medically ill seniors with depression (PROMISE-D trial): Study protocol and design. BMC Psychiatry. 2012;12(1):207.CrossRefPubMedPubMedCentral
26.
go back to reference de Groot V, Beckerman H, Lankhorst GJ, Bouter LM. How to measure comorbidity: A critical review of available methods. J Clin Epidemiol. 2003;56(3):221–9.CrossRefPubMed de Groot V, Beckerman H, Lankhorst GJ, Bouter LM. How to measure comorbidity: A critical review of available methods. J Clin Epidemiol. 2003;56(3):221–9.CrossRefPubMed
27.
go back to reference Yesavage JA, Brink T, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatr Res. 1983;17(1):37–49.CrossRef Yesavage JA, Brink T, Rose TL, Lum O, Huang V, Adey M, Leirer VO. Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatr Res. 1983;17(1):37–49.CrossRef
28.
go back to reference Almeida OP, Almeida SA. Short versions of the geriatric depression scale: a study of their validity for the diagnosis of a major depressive episode according to ICD-10 and DSM-IV. Int J Geriatr Psychiatry. 1999;14(10):858–65.CrossRefPubMed Almeida OP, Almeida SA. Short versions of the geriatric depression scale: a study of their validity for the diagnosis of a major depressive episode according to ICD-10 and DSM-IV. Int J Geriatr Psychiatry. 1999;14(10):858–65.CrossRefPubMed
29.
go back to reference Debruyne H, Van Buggenhout M, Le Bastard N, Aries M, Audenaert K, De Deyn PP, Engelborghs S. Is the geriatric depression scale a reliable screening tool for depressive symptoms in elderly patients with cognitive impairment? Int J Geriatr Psychiatry. 2009;24(6):556–62.CrossRefPubMed Debruyne H, Van Buggenhout M, Le Bastard N, Aries M, Audenaert K, De Deyn PP, Engelborghs S. Is the geriatric depression scale a reliable screening tool for depressive symptoms in elderly patients with cognitive impairment? Int J Geriatr Psychiatry. 2009;24(6):556–62.CrossRefPubMed
30.
go back to reference Ohnhaus EE, Adler R. Methodological problems in the measurement of pain: A comparison between the verbal rating scale and the visual analogue scale. Pain. 1975;1(4):379–84.CrossRefPubMed Ohnhaus EE, Adler R. Methodological problems in the measurement of pain: A comparison between the verbal rating scale and the visual analogue scale. Pain. 1975;1(4):379–84.CrossRefPubMed
32.
go back to reference Collins SL, Moore RA, McQuay HJ. The visual analogue pain intensity scale: What is moderate pain in millimetres? Pain. 1997;72(1):95–7.CrossRefPubMed Collins SL, Moore RA, McQuay HJ. The visual analogue pain intensity scale: What is moderate pain in millimetres? Pain. 1997;72(1):95–7.CrossRefPubMed
33.
go back to reference Gandy M, Sharpe L, Perry KN, Miller L, Thayer Z, Boserio J, Mohamed A. Rates of DSM-IV mood, anxiety disorders, and suicidality in Australian adult epilepsy outpatients: A comparison of well-controlled versus refractory epilepsy. Epilepsy Behav. 2013;26(1):29–35.CrossRefPubMed Gandy M, Sharpe L, Perry KN, Miller L, Thayer Z, Boserio J, Mohamed A. Rates of DSM-IV mood, anxiety disorders, and suicidality in Australian adult epilepsy outpatients: A comparison of well-controlled versus refractory epilepsy. Epilepsy Behav. 2013;26(1):29–35.CrossRefPubMed
34.
go back to reference Zhang MW, Ho R, Cheung MW, Fu E, Mak A. Prevalence of depressive symptoms in patients with chronic obstructive pulmonary disease: A systematic review, meta-analysis and meta-regression. Gen Hosp Psychiatry. 2011;33(3):217–23.CrossRefPubMed Zhang MW, Ho R, Cheung MW, Fu E, Mak A. Prevalence of depressive symptoms in patients with chronic obstructive pulmonary disease: A systematic review, meta-analysis and meta-regression. Gen Hosp Psychiatry. 2011;33(3):217–23.CrossRefPubMed
35.
go back to reference Nouwen A, Winkley K, Twisk J, Lloyd C, Peyrot M, Ismail K, Pouwer F. Type 2 diabetes mellitus as a risk factor for the onset of depression: A systematic review and meta-analysis. Diabetologia. 2010;53(12):2480–6.CrossRefPubMedPubMedCentral Nouwen A, Winkley K, Twisk J, Lloyd C, Peyrot M, Ismail K, Pouwer F. Type 2 diabetes mellitus as a risk factor for the onset of depression: A systematic review and meta-analysis. Diabetologia. 2010;53(12):2480–6.CrossRefPubMedPubMedCentral
36.
go back to reference Solano JP, Gomes B, Higginson IJ. A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manag. 2006;31(1):58–69.CrossRef Solano JP, Gomes B, Higginson IJ. A comparison of symptom prevalence in far advanced cancer, AIDS, heart disease, chronic obstructive pulmonary disease and renal disease. J Pain Symptom Manag. 2006;31(1):58–69.CrossRef
37.
go back to reference Houtjes W, van Meijel B, Deeg D, Beekman A. Unmet needs of outpatients with late-life depression; a comparison of patient, staff and carer perceptions. J Affect Disord. 2011;134(1):242–8.CrossRefPubMed Houtjes W, van Meijel B, Deeg D, Beekman A. Unmet needs of outpatients with late-life depression; a comparison of patient, staff and carer perceptions. J Affect Disord. 2011;134(1):242–8.CrossRefPubMed
38.
go back to reference Kress H-G, Ahlbeck K, Aldington D, Alon E, Coaccioli S, Coluzzi F, Huygen F, Jaksch W, Kalso E, Kocot-Kepska M. Managing chronic pain in elderly patients requires a CHANGE of approach. Curr Med Res Opin. 2014;30(6):1153–64.CrossRefPubMed Kress H-G, Ahlbeck K, Aldington D, Alon E, Coaccioli S, Coluzzi F, Huygen F, Jaksch W, Kalso E, Kocot-Kepska M. Managing chronic pain in elderly patients requires a CHANGE of approach. Curr Med Res Opin. 2014;30(6):1153–64.CrossRefPubMed
40.
go back to reference Prina AM, Deeg D, Brayne C, Beekman A, Huisman M. The association between depressive symptoms and non-psychiatric hospitalisation in older adults. PLoS One. 2012;7(4):e34821.CrossRefPubMedPubMedCentral Prina AM, Deeg D, Brayne C, Beekman A, Huisman M. The association between depressive symptoms and non-psychiatric hospitalisation in older adults. PLoS One. 2012;7(4):e34821.CrossRefPubMedPubMedCentral
41.
go back to reference Lindwall M, Larsman P, Hagger MS. The reciprocal relationship between physical activity and depression in older European adults: A prospective cross-lagged panel design using SHARE data. Health Psychol. 2011;30(4):453.CrossRefPubMed Lindwall M, Larsman P, Hagger MS. The reciprocal relationship between physical activity and depression in older European adults: A prospective cross-lagged panel design using SHARE data. Health Psychol. 2011;30(4):453.CrossRefPubMed
42.
go back to reference Pan A, Sun Q, Okereke OI, Rexrode KM, Hu FB. Depression and risk of stroke morbidity and mortality: A meta-analysis and systematic review. J Am Med Assoc. 2011;306(11):1241–9.CrossRef Pan A, Sun Q, Okereke OI, Rexrode KM, Hu FB. Depression and risk of stroke morbidity and mortality: A meta-analysis and systematic review. J Am Med Assoc. 2011;306(11):1241–9.CrossRef
43.
go back to reference Kroenke K, Wu J, Bair MJ, Krebs EE, Damush TM, Tu W. Reciprocal relationship between pain and depression: A 12-month longitudinal analysis in primary care. J Pain. 2011;12(9):964–73.CrossRefPubMedPubMedCentral Kroenke K, Wu J, Bair MJ, Krebs EE, Damush TM, Tu W. Reciprocal relationship between pain and depression: A 12-month longitudinal analysis in primary care. J Pain. 2011;12(9):964–73.CrossRefPubMedPubMedCentral
44.
go back to reference Caughey GE, Roughead EE, Shakib S, McDermott RA, Vitry AI, Gilbert AL. Comorbidity of chronic disease and potential treatment conflicts in older people dispensed antidepressants. Age Ageing. 2010;39(4):488–94.CrossRefPubMed Caughey GE, Roughead EE, Shakib S, McDermott RA, Vitry AI, Gilbert AL. Comorbidity of chronic disease and potential treatment conflicts in older people dispensed antidepressants. Age Ageing. 2010;39(4):488–94.CrossRefPubMed
45.
go back to reference Hwang U, Platts-Mills T. Pain management in the elderly. In: Kahn JH, Magauran BG, Olshaker JS, editors. Geriatric Emergency Medicine: Principles and Practice. New York: Cambridge University Press; 2014. p. 69. Hwang U, Platts-Mills T. Pain management in the elderly. In: Kahn JH, Magauran BG, Olshaker JS, editors. Geriatric Emergency Medicine: Principles and Practice. New York: Cambridge University Press; 2014. p. 69.
46.
go back to reference Solomon DH, Rassen JA, Glynn RJ, Lee J, Levin R, Schneeweiss S. The comparative safety of analgesics in older adults with arthritis. Arch Intern Med. 2010;170(22):1968–78.CrossRefPubMed Solomon DH, Rassen JA, Glynn RJ, Lee J, Levin R, Schneeweiss S. The comparative safety of analgesics in older adults with arthritis. Arch Intern Med. 2010;170(22):1968–78.CrossRefPubMed
47.
go back to reference Coupland C, Dhiman P, Morriss R, Arthur A, Barton G, Hippisley-Cox J. Antidepressant use and risk of adverse outcomes in older people: Population based cohort study. Br Med J. 2011;343:d4551.CrossRef Coupland C, Dhiman P, Morriss R, Arthur A, Barton G, Hippisley-Cox J. Antidepressant use and risk of adverse outcomes in older people: Population based cohort study. Br Med J. 2011;343:d4551.CrossRef
48.
go back to reference Almeida OP, Alfonso H, Hankey GJ, Flicker L. Depression, antidepressant use and mortality in later life: the Health In Men Study. PLoS One. 2010;5(6):e11266.CrossRefPubMedPubMedCentral Almeida OP, Alfonso H, Hankey GJ, Flicker L. Depression, antidepressant use and mortality in later life: the Health In Men Study. PLoS One. 2010;5(6):e11266.CrossRefPubMedPubMedCentral
49.
go back to reference Katon WJ, Lin EH, Von Korff M, Ciechanowski P, Ludman EJ, Young B, Peterson D, Rutter CM, McGregor M, McCulloch D. Collaborative care for patients with depression and chronic illnesses. N Engl J Med. 2010;363(27):2611–20.CrossRefPubMedPubMedCentral Katon WJ, Lin EH, Von Korff M, Ciechanowski P, Ludman EJ, Young B, Peterson D, Rutter CM, McGregor M, McCulloch D. Collaborative care for patients with depression and chronic illnesses. N Engl J Med. 2010;363(27):2611–20.CrossRefPubMedPubMedCentral
50.
go back to reference Huang AX, Delucchi K, Dunn LB, Nelson JC. A systematic review and meta-analysis of psychotherapy for late-life depression. Am J Geriatr Psychiatry. 2014;23(3):261–73.CrossRefPubMed Huang AX, Delucchi K, Dunn LB, Nelson JC. A systematic review and meta-analysis of psychotherapy for late-life depression. Am J Geriatr Psychiatry. 2014;23(3):261–73.CrossRefPubMed
51.
go back to reference Cuijpers P, van Straten A, Smit F. Psychological treatment of late-life depression: A meta-analysis of randomized controlled trials. Int J Geriatr Psychiatry. 2006;21(12):1139–49.CrossRefPubMed Cuijpers P, van Straten A, Smit F. Psychological treatment of late-life depression: A meta-analysis of randomized controlled trials. Int J Geriatr Psychiatry. 2006;21(12):1139–49.CrossRefPubMed
52.
go back to reference Pinquart DP, Lyness J. Treatments for later-life depressive conditions: A meta-analytic comparison of pharmacotherapy and psychotherapy. Am J Psychiatry. 2006;163(9):1493–501.CrossRefPubMed Pinquart DP, Lyness J. Treatments for later-life depressive conditions: A meta-analytic comparison of pharmacotherapy and psychotherapy. Am J Psychiatry. 2006;163(9):1493–501.CrossRefPubMed
53.
go back to reference Pinquart DP, Lyness J. Effects of psychotherapy and other behavioral interventions on clinically depressed older adults: A meta-analysis. Aging Ment Health. 2007;11(6):645–57.CrossRefPubMed Pinquart DP, Lyness J. Effects of psychotherapy and other behavioral interventions on clinically depressed older adults: A meta-analysis. Aging Ment Health. 2007;11(6):645–57.CrossRefPubMed
54.
go back to reference Andersson G, Johansson C, Nordlander A, Asmundson GJ. Chronic pain in older adults: A controlled pilot trial of a brief cognitive-behavioural group treatment. Behav Cogn Psychother. 2012;40(02):239–44.CrossRefPubMed Andersson G, Johansson C, Nordlander A, Asmundson GJ. Chronic pain in older adults: A controlled pilot trial of a brief cognitive-behavioural group treatment. Behav Cogn Psychother. 2012;40(02):239–44.CrossRefPubMed
55.
go back to reference Nicholas MK, Asghari A, Blyth FM, Wood BM, Murray R, McCabe R, Brnabic A, Beeston L, Corbett M, Sherrington C. Self-management intervention for chronic pain in older adults: A randomised controlled trial. Pain. 2013;154(6):824–35.CrossRefPubMed Nicholas MK, Asghari A, Blyth FM, Wood BM, Murray R, McCabe R, Brnabic A, Beeston L, Corbett M, Sherrington C. Self-management intervention for chronic pain in older adults: A randomised controlled trial. Pain. 2013;154(6):824–35.CrossRefPubMed
56.
go back to reference McGuire BE, Nicholas MK, Asghari A, Wood BM, Main CJ. The effectiveness of psychological treatments for chronic pain in older adults: Cautious optimism and an agenda for research. Curr. Opin. Psychiatry. 2014;27(5):380–4.CrossRefPubMed McGuire BE, Nicholas MK, Asghari A, Wood BM, Main CJ. The effectiveness of psychological treatments for chronic pain in older adults: Cautious optimism and an agenda for research. Curr. Opin. Psychiatry. 2014;27(5):380–4.CrossRefPubMed
57.
go back to reference Blyth FM, Rochat S, Cumming RG, Creasey H, Handelsman D, Le Couteur DG, Naganathan V, Sambrook PN, Seibel MJ, Waite LM. Pain, frailty and comorbidity in older men: The CHAMP study. Pain. 2008;140:224–30.CrossRefPubMed Blyth FM, Rochat S, Cumming RG, Creasey H, Handelsman D, Le Couteur DG, Naganathan V, Sambrook PN, Seibel MJ, Waite LM. Pain, frailty and comorbidity in older men: The CHAMP study. Pain. 2008;140:224–30.CrossRefPubMed
58.
go back to reference Mangin D, Heath I, Jamoulle M. Beyond diagnosis: Rising to the multimorbidity challenge. Br Med J. 2012;345(7865):11. Mangin D, Heath I, Jamoulle M. Beyond diagnosis: Rising to the multimorbidity challenge. Br Med J. 2012;345(7865):11.
59.
go back to reference Chou KR. Reciprocal relationship between pain and depression in older adults: evidence from the English Longitudinal Study of Ageing. J Affect Disord. 2007;102(1):115–23.CrossRefPubMed Chou KR. Reciprocal relationship between pain and depression in older adults: evidence from the English Longitudinal Study of Ageing. J Affect Disord. 2007;102(1):115–23.CrossRefPubMed
60.
go back to reference Lyketsos CG, Lopez O, Jones B, Fitzpatrick AL, Breitner J, DeKosky S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA. 2002;288(12):1475–83.CrossRefPubMed Lyketsos CG, Lopez O, Jones B, Fitzpatrick AL, Breitner J, DeKosky S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA. 2002;288(12):1475–83.CrossRefPubMed
Metadata
Title
Pain severity predicts depressive symptoms over and above individual illnesses and multimorbidity in older adults
Authors
Louise Sharpe
Sarah McDonald
Helen Correia
Patrick J. Raue
Tanya Meade
Michael Nicholas
Patricia Arean
Publication date
01-12-2017
Publisher
BioMed Central
Published in
BMC Psychiatry / Issue 1/2017
Electronic ISSN: 1471-244X
DOI
https://doi.org/10.1186/s12888-017-1334-y

Other articles of this Issue 1/2017

BMC Psychiatry 1/2017 Go to the issue