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Published in: BMC Pediatrics 1/2024

Open Access 01-12-2024 | Research

The Minhang Pediatric Biobank cohort study: protocol overview and baseline characteristics

Authors: Xiaosa Wen, Xinyue Zhang, Yun Qiu, Yaqin Wang, Liujie Zhu, Tao Liu, Zengliang Ruan

Published in: BMC Pediatrics | Issue 1/2024

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Abstract

Background

Little has been done to establish biobanks for studying the environment and lifestyle risk factors for diseases among the school-age children. The Minhang Pediatric Biobank (MPB) cohort study aims to identify factors associated with health and diseases of school-aged children living in the urban or suburban area of Shanghai.

Methods

This population-based cohort study was started in all sub-districts/towns of Minhang district of Shanghai in 2014. First-grade students in elementary school were enrolled during the time of their routine physical examinations, with self-administered questionnaires completed by their primary caregivers. Additional information was extracted from multiple health information systems. Urine and saliva samples were collected during the baseline survey and follow-up visits.

Results

At the end of 2014 academic year, a total number of 8412 children and their parents were recruited, including 4339 boys and 4073 girls. All the participants completed the baseline survey and physical examination, and 7128 urine and 2767 saliva samples were collected. The five most prevalent childhood diseases in this population were dental caries, bronchitis, pneumonia, asthma and overweight/obese.

Conclusions

The MPB cohort has been successfully established, serving as a useful platform for future research relating to the genetic, environmental and lifestyle risk factors for childhood diseases.
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Metadata
Title
The Minhang Pediatric Biobank cohort study: protocol overview and baseline characteristics
Authors
Xiaosa Wen
Xinyue Zhang
Yun Qiu
Yaqin Wang
Liujie Zhu
Tao Liu
Zengliang Ruan
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Pediatrics / Issue 1/2024
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-024-04763-6

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