Skip to main content
Top
Published in: BMC Pediatrics 1/2018

Open Access 01-12-2018 | Research article

Otologic, audiometric and speech findings in patients undergoing surgery for cleft palate

Published in: BMC Pediatrics | Issue 1/2018

Login to get access

Abstract

Background

Although considerable progress has been made in the last 30 years in the treatment of cleft palate (CP), a multidisciplinary approach combining examinations by a paediatrician, maxillofacial surgeon, otolaryngologist and speech and language pathologist followed by surgical operation is still required. In this work, we performed an observational cross-sectional study to determine whether the CP grade or number of ventilation tubes received was associated with tympanic membrane abnormalities, hearing loss or speech outcomes.

Methods

Otologic, audiometric, tympanometric and speech evaluations were performed in a cohort of 121 patients (children > 6 years) who underwent an operation for CP at the Vall d’Hebron Hospital, Barcelona from 2000 to 2014.

Results

The most and least frequent CP types evaluated according to the Veau grade were type III (55.37%) and I (8.26%), respectively. A normal appearance of the membrane was observed in 58% individuals, of whom 55% never underwent ventilation ear tube insertion. No statistically significant associations were identified between the CP type and number of surgeries for insertion of tubes (p = 0.820). The degree of hearing loss (p = 0.616), maximum impedance (p = 0.800) and tympanic membrane abnormalities indicative of chronic otitis media (COM) (p = 0.505) among examined patients revealed no statistically significant association with the grade of CP. However, an association was identified between hypernasality and the grade of CP (p = 0.053), COM (p = 0.000), hearing loss (p = 0.000) and number of inserted ventilation tubes.

Conclusion

Although the placement of tympanic ventilation tubes has been accompanied by an increased rate of COM, it is still important to assess whether this is a result of the number of ventilation tubes inserted or it is intrinsic to the natural history of middle ear inflammatory disease of such patients.
Our results do not support improvements in speech, hearing, or tympanic membrane abnormalities with more aggressive management of COM with tympanostomy tubes.
Literature
1.
go back to reference Shaye D, Liu CC, Tollefson TT. Cleft Lip and Palate: an evidence-based review. Facial Plast Surg Clin North Am. 2015;23(3):357–72.CrossRef Shaye D, Liu CC, Tollefson TT. Cleft Lip and Palate: an evidence-based review. Facial Plast Surg Clin North Am. 2015;23(3):357–72.CrossRef
2.
go back to reference Steinberg JP, Gosain AK. Thirty years of prenatal cleft diagnosis: what have we learned? Plast Reconstr Surg. 2015;136(3):550–7.CrossRef Steinberg JP, Gosain AK. Thirty years of prenatal cleft diagnosis: what have we learned? Plast Reconstr Surg. 2015;136(3):550–7.CrossRef
3.
go back to reference Taib BG, Taib AG, Swift AC, van Eeden S. Cleft lip and palate: diagnosis and management. Br J Hosp Med (Lond). 2015;76(10):584–5 588-591.CrossRef Taib BG, Taib AG, Swift AC, van Eeden S. Cleft lip and palate: diagnosis and management. Br J Hosp Med (Lond). 2015;76(10):584–5 588-591.CrossRef
4.
go back to reference Shkoukani MA, Lawrence LA, Liebertz DJ, Svider PF. Cleft palate: a clinical review. Birth Defects Res C Embryo Today. 2014;102(4):333–42.CrossRef Shkoukani MA, Lawrence LA, Liebertz DJ, Svider PF. Cleft palate: a clinical review. Birth Defects Res C Embryo Today. 2014;102(4):333–42.CrossRef
5.
go back to reference Sharma RK, Nanda V. Problems of middle ear and hearing in cleft children. Indian J Plast Surg. 2009;42(Suppl):S144–8.CrossRef Sharma RK, Nanda V. Problems of middle ear and hearing in cleft children. Indian J Plast Surg. 2009;42(Suppl):S144–8.CrossRef
6.
go back to reference Skuladottir H, Sivertsen A, Assmus J, Remme AR, Dahlen M, Vindenes H. Hearing outcomes in patients with cleft lip/palate. Cleft Palate Craniofacial J. 2015;52(2):e23–31.CrossRef Skuladottir H, Sivertsen A, Assmus J, Remme AR, Dahlen M, Vindenes H. Hearing outcomes in patients with cleft lip/palate. Cleft Palate Craniofacial J. 2015;52(2):e23–31.CrossRef
7.
go back to reference Flynn T, Persson C, Moller C, Lohmander A, Magnusson L. A longitudinal study of hearing and middle ear status of individuals with cleft palate with and without additional malformations/syndromes. Cleft Palate Craniofac J. 2014;51(5):e94–e101.CrossRef Flynn T, Persson C, Moller C, Lohmander A, Magnusson L. A longitudinal study of hearing and middle ear status of individuals with cleft palate with and without additional malformations/syndromes. Cleft Palate Craniofac J. 2014;51(5):e94–e101.CrossRef
8.
go back to reference Alper CM, Losee JE, Mandel EM, Seroky JT, Swarts JD, Doyle WJ. Postpalatoplasty Eustachian tube function in young children with cleft palate. Cleft Palate-Craniofacial J. 2012a;49(4):504–7.CrossRef Alper CM, Losee JE, Mandel EM, Seroky JT, Swarts JD, Doyle WJ. Postpalatoplasty Eustachian tube function in young children with cleft palate. Cleft Palate-Craniofacial J. 2012a;49(4):504–7.CrossRef
9.
go back to reference Alper CM, Losee JE, Mandel EM, Seroky JT, Swarts JD, Doyle WJ. Pre- and post-palatoplasty Eustachian tube function in infants with cleft palate. Int J Pediatr Otorhinolaryngol. 2012b;76(3):388–91.CrossRef Alper CM, Losee JE, Mandel EM, Seroky JT, Swarts JD, Doyle WJ. Pre- and post-palatoplasty Eustachian tube function in infants with cleft palate. Int J Pediatr Otorhinolaryngol. 2012b;76(3):388–91.CrossRef
10.
go back to reference Carroll DJ, Padgitt NR, Liu M, Timothy AL, Tibesar RJ, Sidman JD. The effect of cleft palate repair technique on hearing outcomes in children. Int J Pediatr Otorhinolaryngol. 2013;77(9):1518–22.CrossRef Carroll DJ, Padgitt NR, Liu M, Timothy AL, Tibesar RJ, Sidman JD. The effect of cleft palate repair technique on hearing outcomes in children. Int J Pediatr Otorhinolaryngol. 2013;77(9):1518–22.CrossRef
11.
go back to reference Smith LK, Gubbels SP, MacArthur CJ, Milczuk HA. The effect of the palatoplasty method on the frequency of ear tube placement. Arch Otolaryngol Head Neck Surg. 2008;134(10):1085–9.CrossRef Smith LK, Gubbels SP, MacArthur CJ, Milczuk HA. The effect of the palatoplasty method on the frequency of ear tube placement. Arch Otolaryngol Head Neck Surg. 2008;134(10):1085–9.CrossRef
12.
go back to reference Cable BB, Mair EA. Avoiding perils and pitfalls in velocardiofacial syndrome: an otolaryngologist’s perspective. Ear Nose Throat J. 2003;82(1):56–60.PubMed Cable BB, Mair EA. Avoiding perils and pitfalls in velocardiofacial syndrome: an otolaryngologist’s perspective. Ear Nose Throat J. 2003;82(1):56–60.PubMed
13.
go back to reference Berryhill W. Otologic concerns for cleft lip and palate patient. Oral Maxillofac Surg Clin North Am. 2016;28(2):177–9.CrossRef Berryhill W. Otologic concerns for cleft lip and palate patient. Oral Maxillofac Surg Clin North Am. 2016;28(2):177–9.CrossRef
14.
go back to reference Harman NL, Bruce IA, Kirkham JJ, Tierney S, Callery P, O'Brien K, Bennett A, Chorbachi R, Hall PN, Harding-Bell A, et al. The importance of integration of stakeholder views in Core outcome set development: otitis media with effusion in children with cleft palate. PLoS One. 2015;10(6):e0129514.CrossRef Harman NL, Bruce IA, Kirkham JJ, Tierney S, Callery P, O'Brien K, Bennett A, Chorbachi R, Hall PN, Harding-Bell A, et al. The importance of integration of stakeholder views in Core outcome set development: otitis media with effusion in children with cleft palate. PLoS One. 2015;10(6):e0129514.CrossRef
15.
go back to reference Handzić-CuK J, CuK V, Risavi R, Katusić D, Stajner-Katusić S. Hearing levels and age in cleft palate patients. Int J Pediatr Otorhinolaryngol. 1996;37(3):227–42.CrossRef Handzić-CuK J, CuK V, Risavi R, Katusić D, Stajner-Katusić S. Hearing levels and age in cleft palate patients. Int J Pediatr Otorhinolaryngol. 1996;37(3):227–42.CrossRef
16.
go back to reference Bluestone CD, Fria TJ, Arjona SK, Casselbrant ML, Schwartz DM, Ruben RJ, Gates GA, Downs MP, Northern JL, Jerger JF, et al. Controversies in screening for middle ear disease and hearing loss in children. Pediatrics. 1986;77(1):57–70.PubMed Bluestone CD, Fria TJ, Arjona SK, Casselbrant ML, Schwartz DM, Ruben RJ, Gates GA, Downs MP, Northern JL, Jerger JF, et al. Controversies in screening for middle ear disease and hearing loss in children. Pediatrics. 1986;77(1):57–70.PubMed
17.
go back to reference Sheahan P, Miller I, Sheahan JN, Earley MJ, Blayney AW. Incidence and outcome of middle ear disease in cleft lip and/or cleft palate. Int J Pediatr Otorhinolaryngol. 2003;67(7):785–93.CrossRef Sheahan P, Miller I, Sheahan JN, Earley MJ, Blayney AW. Incidence and outcome of middle ear disease in cleft lip and/or cleft palate. Int J Pediatr Otorhinolaryngol. 2003;67(7):785–93.CrossRef
18.
go back to reference He L, Zhang J, Liu Q, Yin H, Lech M, Huang Y. Automatic evaluation of hypernasality based on a cleft palate speech database. J Med Syst. 2015;39(5):61.CrossRef He L, Zhang J, Liu Q, Yin H, Lech M, Huang Y. Automatic evaluation of hypernasality based on a cleft palate speech database. J Med Syst. 2015;39(5):61.CrossRef
19.
go back to reference Ahn JH, Kang WS, Kim JH, Koh KS, Yoon TH. Clinical manifestation and risk factors of children with cleft palate receiving repeated ventilating tube insertions for treatment of recurrent otitis media with effusion. Acta Otolaryngol. 2012;132(7):702–7.CrossRef Ahn JH, Kang WS, Kim JH, Koh KS, Yoon TH. Clinical manifestation and risk factors of children with cleft palate receiving repeated ventilating tube insertions for treatment of recurrent otitis media with effusion. Acta Otolaryngol. 2012;132(7):702–7.CrossRef
20.
go back to reference Aydınlı FE, Özcebe E, Kulak Kayıkçı ME, Yılmaz T, Özgür FF. Investigating the effects of glottal stop productions on voice in children with cleft palate using multidimensional voice assessment methods. J Voice. 2015;30(6):763 e9.PubMed Aydınlı FE, Özcebe E, Kulak Kayıkçı ME, Yılmaz T, Özgür FF. Investigating the effects of glottal stop productions on voice in children with cleft palate using multidimensional voice assessment methods. J Voice. 2015;30(6):763 e9.PubMed
21.
go back to reference Keuning KHDM, Wieneke GH, van Wijngaarden HA, Dejonckere PH. The correlation between nasalance and a differentiated perceptual rating of speech in Dutch patients with velopharyngeal insufficiency. Cleft Palate Craniofacial J. 2002;39(3):277–84.CrossRef Keuning KHDM, Wieneke GH, van Wijngaarden HA, Dejonckere PH. The correlation between nasalance and a differentiated perceptual rating of speech in Dutch patients with velopharyngeal insufficiency. Cleft Palate Craniofacial J. 2002;39(3):277–84.CrossRef
22.
go back to reference Zheng W, Smith JD, Shi B, Li Y, Wang Y, Li S, Meng Z, Zheng Q. The natural history of audiologic and tympanometric findings inpatients with an unrepaired cleft palate. Cleft Palate Craniofacial J. 2009;46(1):24–9.CrossRef Zheng W, Smith JD, Shi B, Li Y, Wang Y, Li S, Meng Z, Zheng Q. The natural history of audiologic and tympanometric findings inpatients with an unrepaired cleft palate. Cleft Palate Craniofacial J. 2009;46(1):24–9.CrossRef
23.
go back to reference Tunçbilek G, Ózgür F, Belgin E. Audiologic and Tympanometric findngs in children with cleft lip and palate. Cleft Palate Craniofacial J. 2003;40(3):304–9.CrossRef Tunçbilek G, Ózgür F, Belgin E. Audiologic and Tympanometric findngs in children with cleft lip and palate. Cleft Palate Craniofacial J. 2003;40(3):304–9.CrossRef
24.
go back to reference Doyle WJ, Reilly JS, Jardini L, Rovnak S. Effect of palatoplasty on the function of the Eustachian tube in children with cleft palate. Cleft Palate J. 1986;23(1):63–8.PubMed Doyle WJ, Reilly JS, Jardini L, Rovnak S. Effect of palatoplasty on the function of the Eustachian tube in children with cleft palate. Cleft Palate J. 1986;23(1):63–8.PubMed
25.
go back to reference Shaw R, Richardson D, McMahon S. Conservative management of otitis media in cleft palate. J Craniomaxillofac Surg. 2003;31(5):316–20.CrossRef Shaw R, Richardson D, McMahon S. Conservative management of otitis media in cleft palate. J Craniomaxillofac Surg. 2003;31(5):316–20.CrossRef
26.
go back to reference Smillie I, Robertson S, Yule A, Wynne DM, Russell CJH. Complications of ventilation tube insertion in children with and without cleft palate: a nested case-control comparison. JAMA Otolaryngol Head Neck Surg. 2014;140(10):940–3.CrossRef Smillie I, Robertson S, Yule A, Wynne DM, Russell CJH. Complications of ventilation tube insertion in children with and without cleft palate: a nested case-control comparison. JAMA Otolaryngol Head Neck Surg. 2014;140(10):940–3.CrossRef
27.
go back to reference Ovesen T, Blegvad-Andersen R. Alterations in tympanic membrane appearance in middle ear funcition in 11- year-old children with complete unilateral cleft lip and palate compared with healthy agematched subjects. Clin Otolaryngol. 1992;17:203–7.CrossRef Ovesen T, Blegvad-Andersen R. Alterations in tympanic membrane appearance in middle ear funcition in 11- year-old children with complete unilateral cleft lip and palate compared with healthy agematched subjects. Clin Otolaryngol. 1992;17:203–7.CrossRef
28.
go back to reference Robson AK, Blanshard JD, Jones K, Albery EH, Smith IM, Maw AR. A conservative approach to the management of otitis media with effusion in cleft palate children. J Laryngol Otol. 1992;106(9):788–92.CrossRef Robson AK, Blanshard JD, Jones K, Albery EH, Smith IM, Maw AR. A conservative approach to the management of otitis media with effusion in cleft palate children. J Laryngol Otol. 1992;106(9):788–92.CrossRef
29.
go back to reference Kay DJ, Nelson M, Rosenfeld RM. Meta-analysis of tympanostomy tube sequelae. Otolaryngol Head Neck Surg. 2001;124(4):374–80.CrossRef Kay DJ, Nelson M, Rosenfeld RM. Meta-analysis of tympanostomy tube sequelae. Otolaryngol Head Neck Surg. 2001;124(4):374–80.CrossRef
30.
go back to reference Brgoch MS, Dodson KM, Kim TC, Kim DM, Trivelpiece R, Rhodes JL. Timing of Tympanostomy tube placement and efficacy of Palatoplasty technique on the resolution of chronic otitis media: a cross-sectional analysis. Eplasty. 2015;15:e32.PubMedPubMedCentral Brgoch MS, Dodson KM, Kim TC, Kim DM, Trivelpiece R, Rhodes JL. Timing of Tympanostomy tube placement and efficacy of Palatoplasty technique on the resolution of chronic otitis media: a cross-sectional analysis. Eplasty. 2015;15:e32.PubMedPubMedCentral
31.
go back to reference Hanes LA, Murphy A, Hatchette JE, Delorey R, Wilson KL, Hong P, Bezuhly M. Chronic otitis media with effusion is associated with increased risk of secondary speech surgery. Plast Reconstr Surg. 2015;136(2):343–9.CrossRef Hanes LA, Murphy A, Hatchette JE, Delorey R, Wilson KL, Hong P, Bezuhly M. Chronic otitis media with effusion is associated with increased risk of secondary speech surgery. Plast Reconstr Surg. 2015;136(2):343–9.CrossRef
32.
go back to reference Richman LC, Eliason M. Psychological characteristics of children with cleft lip and palate: intellectual, achievement, behavioral and personality variables. Cleft Palate J. 1982;19(4):249–57.PubMed Richman LC, Eliason M. Psychological characteristics of children with cleft lip and palate: intellectual, achievement, behavioral and personality variables. Cleft Palate J. 1982;19(4):249–57.PubMed
33.
go back to reference Sundman H, Flynn T, Tengroth B, Lohmander A. ABR thresholds in infants born with CLP and OME and infants with OME. Int J Pediatr Otorhinolaryngol. 2016;81:21–5.CrossRef Sundman H, Flynn T, Tengroth B, Lohmander A. ABR thresholds in infants born with CLP and OME and infants with OME. Int J Pediatr Otorhinolaryngol. 2016;81:21–5.CrossRef
34.
go back to reference Lithovius RH, Lehtonen V, Autio TJ, et al. The association of cleft severity and cleft palate repair technique on hearing outcomes in children in northern Finland. J Craniomaxillofac Surg. 2015;43(9):1863–7.CrossRef Lithovius RH, Lehtonen V, Autio TJ, et al. The association of cleft severity and cleft palate repair technique on hearing outcomes in children in northern Finland. J Craniomaxillofac Surg. 2015;43(9):1863–7.CrossRef
Metadata
Title
Otologic, audiometric and speech findings in patients undergoing surgery for cleft palate
Publication date
01-12-2018
Published in
BMC Pediatrics / Issue 1/2018
Electronic ISSN: 1471-2431
DOI
https://doi.org/10.1186/s12887-018-1312-7

Other articles of this Issue 1/2018

BMC Pediatrics 1/2018 Go to the issue