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BMC Ophthalmology
Published in: BMC Ophthalmology 1/2023

Open Access 01-12-2023 | Case report

A rare presentation of orbital spindle cell carcinoma a case report and brief review of the literature

Authors: Mansooreh Jamshidian Tehrani, Ali Rashidinia, Fahimeh Asadi Amoli, Amirreza Esfandiari

Published in: BMC Ophthalmology | Issue 1/2023

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Abstract

Background

To describe a case of orbital spindle cell carcinoma which presented with limbal ischemia and briefly review the literature.

Methods

Retrospective case report and brief literature review.

Results

A 61-year old man presented with blepharoptosis, periorbital pain, decreased vision and limbal ischemia. He did not mention any previous illness and did not take any kind of drugs. Imaging revealed an orbital mass that was positive for SMA, Vimentin and CD99 and negative for S100. We treated the patient with chemotherapy and followed him for other complications that occurred throughout disease course.

Conclusion

Spindle cell carcinomas are a rare variant of squamous cell carcinoma (SCC) with dual malignant histologic differentiation of squamous and mesenchymal cells. Few cases of orbital spindle cell carcinoma have been reported, which have been either secondary to distant metastasis or regional spread. In this study, we have reported the first case of primary orbital spindle cell carcinoma presenting with limbal ischemia. Further studies are needed to describe the different clinical presentations and management strategies of this rare clinical entity.
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Metadata
Title
A rare presentation of orbital spindle cell carcinoma a case report and brief review of the literature
Authors
Mansooreh Jamshidian Tehrani
Ali Rashidinia
Fahimeh Asadi Amoli
Amirreza Esfandiari
Publication date
01-12-2023
Publisher
BioMed Central
Published in
BMC Ophthalmology / Issue 1/2023
Electronic ISSN: 1471-2415
DOI
https://doi.org/10.1186/s12886-023-03125-7

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