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Published in: BMC Pregnancy and Childbirth 1/2018

Open Access 01-12-2018 | Research article

Accelerating newborn survival in Ghana through a low-dose, high-frequency health worker training approach: a cluster randomized trial

Authors: Patricia P. Gomez, Allyson R. Nelson, Amos Asiedu, Etta Addo, Dora Agbodza, Chantelle Allen, Martha Appiagyei, Cynthia Bannerman, Patience Darko, Julia Duodu, Fred Effah, Hannah Tappis

Published in: BMC Pregnancy and Childbirth | Issue 1/2018

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Abstract

Background

Newborn deaths comprise nearly half of under-5 deaths in Ghana, despite the fact that skilled birth attendants (SBAs) are present at 68% of births, which implies that evidence-based care during labor, birth and the immediate postnatal period may be deficient. We assessed the effect of a low-dose, high-frequency (LDHF) training approach on long-term evidence-based skill retention among SBAs and impact on adverse birth outcomes.

Methods

From 2014 to 2017, we conducted a cluster-randomized trial in 40 hospitals in Ghana. Eligible hospitals were stratified by region and randomly assigned to one of four implementation waves. We assessed the relative risks (RRs) of institutional intrapartum stillbirths and 24-h newborn mortality in months 1–6 and 7–12 of implementation as compared to the historical control period, and in post-intervention facilities compared to pre-intervention facilities during the same period. All SBAs providing labor and delivery care were invited to enroll; their knowledge and skills were assessed pre- and post-training, and 1 year later.

Results

Adjusting for region and health facility type, the RR of 24-h newborn mortality in the 40 enrolled hospitals was 0·41 (95% CI 0·32–0·51; p < 0.001) in months 1–6 and 0·30 (95% CI 0·21–0·43; p < 0·001) in months 7–12 compared to baseline. The adjusted RR of intrapartum stillbirth was 0·64 (95% CI 0·53–0·77; p < 0·001) in months 1–6 and 0·48 (95% CI 0·36–0·63; p < 0·001) in months 7–12 compared to baseline. Four hundred three SBAs consented and enrolled. After 1 year, 200 SBAs assessed had 28% (95% CI 25–32; p < 0·001) and 31% (95% CI 27–36; p < 0·001) higher scores than baseline on low-dose 1 and 2 content skills, respectively.

Conclusions

This training approach results in a sustained decrease in facility-based newborn mortality and intrapartum stillbirths, and retained knowledge and skills among SBAs after a year. We recommend use of this approach for future maternal and newborn health in-service training and programs.

Trial registration

Retrospectively registered on 25 September 2017 at Clinical Trials, identifier NCT03290924.
Appendix
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Footnotes
1
UN Sustainable Development Goals (http://​www.​un.​org/​sustainabledevel​opment/​health/​page/​2/​0; accessed 26 January 2017)
 
2
A skilled attendant is an accredited health professional such as a midwife, doctor, or nurse who has been educated and trained to proficiency in the skills needed to manage normal (uncomplicated) pregnancies, childbirth, and the immediate postnatal period, and in the identification, management, and referral of complications in women and newborns. (WHO, ICM and FIGO. Making pregnancy safer: the critical role of the skilled attendant. A joint statement by WHO, ICM and FIGO. Geneva, 2004.)
 
3
Project Fives Alive! is implemented by the Institute for Healthcare Improvement and the National Catholic Health Service in collaboration with the Ghana Health Service.
 
Literature
2.
go back to reference Liu L, Oza S, Hogan D, et al. Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the sustainable development goals. Lancet. 2016;388:3027–35.CrossRefPubMedPubMedCentral Liu L, Oza S, Hogan D, et al. Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the sustainable development goals. Lancet. 2016;388:3027–35.CrossRefPubMedPubMedCentral
3.
go back to reference Lawn J, Blencowe H, Waiswa P, et al. Stillbirths: rates, risk factors, and acceleration towards 2030. Lancet. 2016;387:587–603.CrossRefPubMed Lawn J, Blencowe H, Waiswa P, et al. Stillbirths: rates, risk factors, and acceleration towards 2030. Lancet. 2016;387:587–603.CrossRefPubMed
4.
go back to reference Ghana Statistical Service (GSS), Ghana Health Service (GHS), and ICF International. Ghana demographic and health survey 2014. Rockville: GSS, GHS, and ICF International; 2015. Ghana Statistical Service (GSS), Ghana Health Service (GHS), and ICF International. Ghana demographic and health survey 2014. Rockville: GSS, GHS, and ICF International; 2015.
5.
go back to reference UNICEF and the World Health Organization. A decade of tracking progress for maternal, newborn and child survival: the 2015 report. Geneva: UNICEF and WHO; 2015. UNICEF and the World Health Organization. A decade of tracking progress for maternal, newborn and child survival: the 2015 report. Geneva: UNICEF and WHO; 2015.
6.
go back to reference Ghana Ministry of Health. Ghana national newborn health strategy and action plan 2014–2018. Accra: Ghana Ministry of Health; 2014. Ghana Ministry of Health. Ghana national newborn health strategy and action plan 2014–2018. Accra: Ghana Ministry of Health; 2014.
7.
go back to reference Ameh CA, van den Broek N. Making it happen: training health-care providers in emergency obstetric and newborn care. Best Pract Res Clin Obstet Gynaecol. 2015;29(215):1077–91.CrossRefPubMed Ameh CA, van den Broek N. Making it happen: training health-care providers in emergency obstetric and newborn care. Best Pract Res Clin Obstet Gynaecol. 2015;29(215):1077–91.CrossRefPubMed
8.
go back to reference Bluestone J, Johnson P, Fullerton J, Carr C, Alderman J, Bon Tempo J. Effective in-service training design and delivery: evidence from an integrative literature review. Hum Resour Health. 2013;11(1):Article 51.CrossRef Bluestone J, Johnson P, Fullerton J, Carr C, Alderman J, Bon Tempo J. Effective in-service training design and delivery: evidence from an integrative literature review. Hum Resour Health. 2013;11(1):Article 51.CrossRef
9.
go back to reference Sutton RM, Niles D, Meaney PA, et al. Low-dose, high-frequency CPR training improves skill retention of in-hospital paediatric providers. Paediatr. 2011;128(1):e145–51.CrossRef Sutton RM, Niles D, Meaney PA, et al. Low-dose, high-frequency CPR training improves skill retention of in-hospital paediatric providers. Paediatr. 2011;128(1):e145–51.CrossRef
10.
go back to reference Anderson JM, Warren JB. Using simulation to enhance the acquisition and retention of clinical skills in neonatology. Semin Perinatol. 2011;35:59–67.CrossRefPubMed Anderson JM, Warren JB. Using simulation to enhance the acquisition and retention of clinical skills in neonatology. Semin Perinatol. 2011;35:59–67.CrossRefPubMed
11.
go back to reference Goldenberg RL, McClure EM, Jobe AH, Kamath-Rayne BD, Gravette MG, Rubens CE. Stillbirths and neonatal mortality as outcomes. Int J Gynecol Obstet. 2013;123:252–3.CrossRef Goldenberg RL, McClure EM, Jobe AH, Kamath-Rayne BD, Gravette MG, Rubens CE. Stillbirths and neonatal mortality as outcomes. Int J Gynecol Obstet. 2013;123:252–3.CrossRef
12.
go back to reference Wall SN, Lee ACC, Niermeyer S, et al. Neonatal resuscitation in low-resource settings: what, who, and how to overcome challenges to scale up? Int J Gynecol Obstet. 2009;107:S47–64.CrossRef Wall SN, Lee ACC, Niermeyer S, et al. Neonatal resuscitation in low-resource settings: what, who, and how to overcome challenges to scale up? Int J Gynecol Obstet. 2009;107:S47–64.CrossRef
13.
go back to reference Ashish KC, Wrammert J, Nelin V, et al. Evaluation of Helping Babies Breathe Quality Improvement Cycle (HBB-QIC) on retention of neonatal resuscitation skills six months after training in Nepal. BMC Pediatr. 2017;17:103.CrossRef Ashish KC, Wrammert J, Nelin V, et al. Evaluation of Helping Babies Breathe Quality Improvement Cycle (HBB-QIC) on retention of neonatal resuscitation skills six months after training in Nepal. BMC Pediatr. 2017;17:103.CrossRef
14.
go back to reference Lawn JE, Kinney M, Lee AC, et al. Reducing intrapartum-related deaths and disability: can the health system deliver? Int J Gynecol Obstet. 2009;107(Suppl 1):S123–40.CrossRef Lawn JE, Kinney M, Lee AC, et al. Reducing intrapartum-related deaths and disability: can the health system deliver? Int J Gynecol Obstet. 2009;107(Suppl 1):S123–40.CrossRef
17.
go back to reference World Health Organization. WHO guidelines on hand hygiene in health care. Geneva: WHO; 2009. World Health Organization. WHO guidelines on hand hygiene in health care. Geneva: WHO; 2009.
18.
go back to reference World Health Organization (WHO) and Pan American Health Organization (PAHO). Decontamination and reprocessing of medical devices for health-care facilities. Geneva: WHO and PAHO; 2016. World Health Organization (WHO) and Pan American Health Organization (PAHO). Decontamination and reprocessing of medical devices for health-care facilities. Geneva: WHO and PAHO; 2016.
19.
go back to reference Downe S, Gyte GM, Dahlen HG, Singata M. Routine vaginal examinations for assessing progress of labour to improve outcomes for women and babies at term (Review). Cochrane Database Syst Rev. 2013;7:CD010088. Downe S, Gyte GM, Dahlen HG, Singata M. Routine vaginal examinations for assessing progress of labour to improve outcomes for women and babies at term (Review). Cochrane Database Syst Rev. 2013;7:CD010088.
21.
go back to reference World Health Organization. WHO recommendations for prevention and treatment of maternal peripartum infections. Geneva: WHO; 2015. World Health Organization. WHO recommendations for prevention and treatment of maternal peripartum infections. Geneva: WHO; 2015.
22.
go back to reference World Health Organization. WHO recommendations for management of common childhood conditions: evidence for technical update of pocket book recommendations. Geneva: WHO; 2012. World Health Organization. WHO recommendations for management of common childhood conditions: evidence for technical update of pocket book recommendations. Geneva: WHO; 2012.
23.
go back to reference von Dadelszen P, Firoz T, Donnay F, et al. Preeclampsia in low and middle income countries—health services lessons learned from the PRE-EMPT (PRE-eclampsia–eclampsia monitoring, prevention & treatment) project. J Obstet Gynaecol Can. 2012;34(10):917–26.CrossRefPubMed von Dadelszen P, Firoz T, Donnay F, et al. Preeclampsia in low and middle income countries—health services lessons learned from the PRE-EMPT (PRE-eclampsia–eclampsia monitoring, prevention & treatment) project. J Obstet Gynaecol Can. 2012;34(10):917–26.CrossRefPubMed
24.
go back to reference Hofmeyr GJ, Haws RA, Bergström S, et al. Obstetric care in low-resource settings: what, who, and how to overcome challenges to scale up? Int J Gynecol Obstet. 2009;107:S21–45.CrossRef Hofmeyr GJ, Haws RA, Bergström S, et al. Obstetric care in low-resource settings: what, who, and how to overcome challenges to scale up? Int J Gynecol Obstet. 2009;107:S21–45.CrossRef
25.
go back to reference American Academy of Pediatrics (AAP). Helping babies breathe provider guide. 2nd ed. AAP: Elk Grove Village; 2016. American Academy of Pediatrics (AAP). Helping babies breathe provider guide. 2nd ed. AAP: Elk Grove Village; 2016.
27.
go back to reference World Health Organization. Guideline: delayed umbilical cord clamping for improved maternal and infant health and nutrition outcomes. Geneva: WHO; 2014. World Health Organization. Guideline: delayed umbilical cord clamping for improved maternal and infant health and nutrition outcomes. Geneva: WHO; 2014.
28.
go back to reference Ghana Statistical Service (GSS), Ghana Health Service (GHS), and Macro International. Ghana maternal health survey 2007. Calverton: GSS, GHS, and Macro International; 2009. Ghana Statistical Service (GSS), Ghana Health Service (GHS), and Macro International. Ghana maternal health survey 2007. Calverton: GSS, GHS, and Macro International; 2009.
29.
go back to reference World Health Organization. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. Geneva: WHO; 2011. World Health Organization. WHO recommendations for prevention and treatment of pre-eclampsia and eclampsia. Geneva: WHO; 2011.
30.
go back to reference World Health Organization. WHO recommendations for the prevention and treatment of postpartum haemorrhage. Geneva: WHO; 2012. World Health Organization. WHO recommendations for the prevention and treatment of postpartum haemorrhage. Geneva: WHO; 2012.
31.
go back to reference Willcox M, Harrison H, Asiedu A, Nelson A, Gomez P, LeFevre A. Incremental cost and cost-effectiveness of low-dose, high-frequency training in basic emergency obstetric and newborn care as compared to status quo: part of a cluster randomized training intervention evaluation in Ghana. Glob Health. 2017;13:88. https://doi.org/10.1186/s12992-017-0313-x. Published online 6 Dec 2017CrossRef Willcox M, Harrison H, Asiedu A, Nelson A, Gomez P, LeFevre A. Incremental cost and cost-effectiveness of low-dose, high-frequency training in basic emergency obstetric and newborn care as compared to status quo: part of a cluster randomized training intervention evaluation in Ghana. Glob Health. 2017;13:88. https://​doi.​org/​10.​1186/​s12992-017-0313-x. Published online 6 Dec 2017CrossRef
Metadata
Title
Accelerating newborn survival in Ghana through a low-dose, high-frequency health worker training approach: a cluster randomized trial
Authors
Patricia P. Gomez
Allyson R. Nelson
Amos Asiedu
Etta Addo
Dora Agbodza
Chantelle Allen
Martha Appiagyei
Cynthia Bannerman
Patience Darko
Julia Duodu
Fred Effah
Hannah Tappis
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2018
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-018-1705-5

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