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BMC Pregnancy and Childbirth
Published in: BMC Pregnancy and Childbirth 1/2015

Open Access 01-12-2015 | Research article

Prior cesarean section is associated with increased preeclampsia risk in a subsequent pregnancy

Authors: Geum Joon Cho, Log Young Kim, Kyung-Jin Min, Ye Na Sung, Soon-Cheol Hong, Min-Jeong Oh, Hong-Seog Seo, Hai-Joong Kim

Published in: BMC Pregnancy and Childbirth | Issue 1/2015

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Abstract

Background

To evaluate the impact of a prior cesarean section on preeclampsia risk in a subsequent pregnancy.

Methods

Study data were collected from the Korea National Health Insurance Claims Database of the Health Insurance Review and Assessment Service for 2006–2010. Patients who had their first delivery in 2006 and subsequent delivery between 2007 and 2010 in Korea were enrolled. The overall incidence of preeclampsia during the second pregnancy was estimated and to evaluate the risk of preeclampsia in the second pregnancy, a model of multivariate logistic regression analysis was performed with preeclampsia as the final outcome

Results

The risk of preeclampsia in any pregnancy was 2.17%; the risk in the first pregnancy was 2.76%, and that in the second pregnancy was 1.15%. During the second pregnancy, the risk of preeclampsia was 13.30% for women who had developed preeclampsia in their first pregnancy and 0.85% for those who had not. In the entire population, prior cesarean section was associated with preeclampsia risk in their subsequent pregnancy (odds ratio [OR], 1.26; 95% confidence interval [CI], 1.13–1.41). Among women with and without preeclampsia in their first pregnancy, a prior cesarean section was associated with preeclampsia risk in their second pregnancy (OR, 1.35; 95% CI, 1.09–1.67; OR, 1.23; 95% CI, 1.08–1.40, respectively).

Conclusions

Our study showed that cesarean section in a first pregnancy was associated with increased preeclampsia risk in the second pregnancy. These results provide physicians with a preeclampsia risk evaluation method for a second pregnancy that they may aid counseling in patients.
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Metadata
Title
Prior cesarean section is associated with increased preeclampsia risk in a subsequent pregnancy
Authors
Geum Joon Cho
Log Young Kim
Kyung-Jin Min
Ye Na Sung
Soon-Cheol Hong
Min-Jeong Oh
Hong-Seog Seo
Hai-Joong Kim
Publication date
01-12-2015
Publisher
BioMed Central
Published in
BMC Pregnancy and Childbirth / Issue 1/2015
Electronic ISSN: 1471-2393
DOI
https://doi.org/10.1186/s12884-015-0447-x

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