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Open Access 01-12-2020 | Acute Kidney Injury | Review

The COVID-19 nephrology compendium: AKI, CKD, ESKD and transplantation

Authors: Sam Kant, Steven P. Menez, Mohamed Hanouneh, Derek M. Fine, Deidra C. Crews, Daniel C. Brennan, C. John Sperati, Bernard G. Jaar

Published in: BMC Nephrology | Issue 1/2020

Abstract

The pandemic of coronavirus disease 2019 (CoVID-19) has been an unprecedented period. The disease afflicts multiple organ systems, with acute kidney injury (AKI) a major complication in seriously ill patients. The incidence of AKI in patients with CoVID-19 is variable across numerous international studies, but the high incidence of AKI and its associated worse outcomes in the critical care setting are a consistent finding. A multitude of patterns and mechanisms of AKI have been elucidated, and novel strategies to address shortage of renal replacement therapy equipment have been implemented. The disease also has had consequences on longitudinal management of patients with chronic kidney disease and end stage kidney disease. Kidney transplant recipients may be especially susceptible to CoVID-19 as a result of immunosuppression, with preliminary studies demonstrating high mortality rates. Increased surveillance of disease with low threshold for testing and adjustment of immunosuppression regimen during acute periods of illness have been recommended.

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Title: The COVID-19 nephrology compendium: AKI, CKD, ESKD and transplantation
Authors: Sam Kant
Steven P. Menez
Mohamed Hanouneh
Derek M. Fine
Deidra C. Crews
Daniel C. Brennan
C. John Sperati
Bernard G. Jaar
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Acute Kidney Injury
COVID-19
Chronic Kidney Disease
Acute Kidney Injury
Published in: BMC Nephrology / Issue 1/2020
Electronic ISSN: 1471-2369
DOI: https://doi.org/10.1186/s12882-020-02112-0

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Other articles of this Issue 1/2020

Survival and analysis of predictors of mortality in patients undergoing replacement renal therapy: a 20-year cohort

Dietary and lifestyle factors for primary prevention of nephrolithiasis: a systematic review and meta-analysis

Outcomes of arteriovenous access among cancer patients requiring chronic haemodialysis

Challenges in the provision of kidney care at the largest public nephrology center in Guatemala: a qualitative study with health professionals

A case report of adult-onset COQ8B nephropathy presenting focal segmental glomerulosclerosis with granular swollen podocytes

Hospital costs and prognosis in end-stage renal disease patients receiving coronary artery bypass grafting

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At a glance: The STEP trials