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BMC Geriatrics

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Open Access 01-12-2023 | Nutrition | Research

Association of nutritional status and comorbidity with long-term survival among community-dwelling older males

Authors: Baicun Hou, Yunjuan Lin, Wangjingyi Zhang, Qiqi Lin, Shengshu Wang, Fansen Meng, Wei Dai, Gangshi Wang

Published in: BMC Geriatrics | Issue 1/2023

Abstract

Background

Estimates of survival in the older can be of benefit in various facets, particularly in medical and individual decision-making. We aim to validate the value of a combination of nutrition status evaluation and comorbidity assessment in predicting long-term survival among community-dwelling older.

Methods

The Charlson Comorbidity Index (CCI) was applied for comprehensive evaluation of comorbidities. Participants were classified into CCI score ≤ 2 and ≥ 3 subgroups. Nutritional status was assessed by using Mini Nutritional Assessment-Short Form (MNA-SF) and Geriatric Nutritional Risk Index (GNRI) evaluations. Mortality rates and survival curves over a 5-year period were compared among subgroups classified by CCI and/or MNA-SF/GNRI evaluations.

Results

A total of 1033 elderly male participants were enrolled in this study, with an average age of 79.44 ± 8.61 years. 108 deceased participants (10.5%) were identified during a follow-up of 5 years. Cox proportional hazards regression analysis showed that age, CCI, MNA-SF and GNRI were independent predictors of 5-year all-cause death in this cohort. Compared to those with normal nutrition status and CCI ≤ 2, the subgroup at risk of malnutrition and CCI ≥ 3 had a significantly higher 5-year all-cause mortality rate (HR = 4.671; 95% CI:2.613–8.351 for MNA-SF and HR = 7.268; 95% CI:3.401–15.530 for GNRI; P < 0.001 for both). Receiver operating characteristic curve analysis demonstrated that a combination of either MNA-SF or GNRI with CCI had significantly better performance than CCI, MNA-SF or GNRI alone in predicting all-cause death.

Conclusion

The combination of nutritional assessment (MNA-SF or GNRI) with CCI can significantly improve the predictive accuracy of long-term mortality outcomes among community-dwelling older males.

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Title: Association of nutritional status and comorbidity with long-term survival among community-dwelling older males
Authors: Baicun Hou
Yunjuan Lin
Wangjingyi Zhang
Qiqi Lin
Shengshu Wang
Fansen Meng
Wei Dai
Gangshi Wang
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Nutrition
Malnutrition
Published in: BMC Geriatrics / Issue 1/2023
Electronic ISSN: 1471-2318
DOI: https://doi.org/10.1186/s12877-023-04413-z

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