Skip to main content
Top
Published in: BMC Primary Care 1/2021

Open Access 01-12-2021 | Care | Research

Increasing the completion rate of the advance directives in primary care setting – a randomized controlled trial

Authors: Cunzhi Xu, Shi Yan, Jade Chee, Emily Pui-Yan Lee, Han Wei Lim, Sarah Woon Ching Lim, Lian Leng Low

Published in: BMC Primary Care | Issue 1/2021

Login to get access

Abstract

Background

The completion rate of Advance Directives (ADs) has been low. This study aims to examine the effectiveness of two interventions 1) active counseling sessions coupled with passive patient education pamphlets, and 2) patient education pamphlets alone, compared with 3) control group (usual care), in increasing the completion rates of ADs in the primary care setting.

Methods

Multicenter randomised controlled trial in four public primary care clinics in Singapore under Singapore Health Services. Randomization was performed via block randomization with Sequential Numbered Opaque Sealed Envelopes. Participants were randomized into 1) active intervention group (both counseling by primary care physicians and patient education pamphlets) or 2) passive intervention group (only patient education pamphlets), and 3) control group (usual care) with follow-up at 6 weeks. The main outcome measure is the proportion of participants who completed / planned to complete) ADs six weeks post-intervention.

Results

Four hundred five participants were eligible to participate in the study. One hundred eighty-eight participants were recruited into the study (response rate = 46.4%), of which 158 completed the study. There was no significant difference between the control group, passive intervention group, and active intervention group, in terms of completion rates of ADs (29.4, 36.4, and 30.8% respectively).

Conclusions

This randomized controlled trial did not support the use of patient education pamphlets with or without active counseling sessions in increasing the completion of ADs in a primary care setting in Singapore. The optimal intervention strategy depends on each health system’s context and resources, taking into consideration patients’ profiles, which deserves further studies.

Trial registration

Registered on April 17, 2018 clinicaltrials.gov (NCT03499847).
Appendix
Available only for authorised users
Literature
2.
go back to reference Htut Y, Shahrul BK, Poi PJH. The views of older Malaysians on advanced directive and advanced care planning: A qualitative study. Asia-Pacific J Public Heal. 2007. Htut Y, Shahrul BK, Poi PJH. The views of older Malaysians on advanced directive and advanced care planning: A qualitative study. Asia-Pacific J Public Heal. 2007.
3.
go back to reference Perkins HS. Controlling death: The false promise of advance directives. Ann Internal Med. 2007;147(1):51–7. Perkins HS. Controlling death: The false promise of advance directives. Ann Internal Med. 2007;147(1):51–7.
5.
go back to reference Konda M, Ananthula A, Baltz A, Pandey Y, Mariam Roy A, Godbole A, et al. Low advance directive completion rates in hospitalized oncology patients: Room for improvement. J Clin Oncol. 2019;37 31_suppl. Konda M, Ananthula A, Baltz A, Pandey Y, Mariam Roy A, Godbole A, et al. Low advance directive completion rates in hospitalized oncology patients: Room for improvement. J Clin Oncol. 2019;37 31_suppl.
6.
go back to reference Dunlay SM, Swetz KM, Mueller PS, Roger VL. Advance directives in community patients with heart failure. Circ Cardiovasc Qual Outcomes. 2012;5(3);283–9. Dunlay SM, Swetz KM, Mueller PS, Roger VL. Advance directives in community patients with heart failure. Circ Cardiovasc Qual Outcomes. 2012;5(3);283–9.
7.
go back to reference Harrison KL, Adrion ER, Ritchie CS, Sudore RL, Smith AK. Low completion and disparities in advance care planning activities among older Medicare beneficiaries. JAMA Internal Medicine. 2016;176(12):1872–5. Harrison KL, Adrion ER, Ritchie CS, Sudore RL, Smith AK. Low completion and disparities in advance care planning activities among older Medicare beneficiaries. JAMA Internal Medicine. 2016;176(12):1872–5.
8.
go back to reference Wang CW, Lebsack A, Sudore RL, Lai JC. Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates. Dig Dis Sci. 2020;66(5):1446–51. Wang CW, Lebsack A, Sudore RL, Lai JC. Low Rates of Advance Care Planning (ACP) Discussions Despite Readiness to Engage in ACP Among Liver Transplant Candidates. Dig Dis Sci. 2020;66(5):1446–51.
9.
go back to reference Tierney WM, Dexter PR, Gramelspacher GP, Perkins AJ, Zhou XH, Wolinsky FD. The effect of discussions about advance directives on patients’ satisfaction with primary care. J Gen Intern Med. 2001;16(1):32–40. Tierney WM, Dexter PR, Gramelspacher GP, Perkins AJ, Zhou XH, Wolinsky FD. The effect of discussions about advance directives on patients’ satisfaction with primary care. J Gen Intern Med. 2001;16(1):32–40.
10.
go back to reference Chambers C V., Diamond JJ, Perkel RL, Lasch LA. Relationship of advance directives to hospital charges in a medicare population. Arch Intern Med. 1994;154(5):541–7. Chambers C V., Diamond JJ, Perkel RL, Lasch LA. Relationship of advance directives to hospital charges in a medicare population. Arch Intern Med. 1994;154(5):541–7.
11.
go back to reference Brinkman-Stoppelenburg A, Rietjens JAC, Van Der Heide A. The effects of advance care planning on end-of-life care: a systematic review. Palliat Med. 2014;28(8):1000–25. Brinkman-Stoppelenburg A, Rietjens JAC, Van Der Heide A. The effects of advance care planning on end-of-life care: a systematic review. Palliat Med. 2014;28(8):1000–25.
12.
go back to reference Kirschner KL. When written advance directives are not enough. Clin Geriatr Med. 2005;21(1):193–209. Kirschner KL. When written advance directives are not enough. Clin Geriatr Med. 2005;21(1):193–209.
13.
go back to reference Low JA, Ng WC, Yap KB, Chan KM. End-of-life Issues - Preferences and Choices of a Group of Elderly Chinese Subjects Attending a Day Care Centre in Singapore. Ann Acad Med Singapore. 2000;29:50–6. Low JA, Ng WC, Yap KB, Chan KM. End-of-life Issues - Preferences and Choices of a Group of Elderly Chinese Subjects Attending a Day Care Centre in Singapore. Ann Acad Med Singapore. 2000;29:50–6.
14.
go back to reference Tay M, Chia SE, Sng J. Knowledge, attitudes and practices of the advance medical directive in a residential estate in Singapore. Ann Acad Med Singapore. 2010;39(6):424. Tay M, Chia SE, Sng J. Knowledge, attitudes and practices of the advance medical directive in a residential estate in Singapore. Ann Acad Med Singapore. 2010;39(6):424.
15.
go back to reference Wissow LS, Belote A, Kramer W, Compton-Phillips A, Kritzler R, Weiner JP. Promoting advance directives among elderly primary care patients. J Gen Intern Med. 2004;19(9):944–51. Wissow LS, Belote A, Kramer W, Compton-Phillips A, Kritzler R, Weiner JP. Promoting advance directives among elderly primary care patients. J Gen Intern Med. 2004;19(9):944–51.
16.
go back to reference Houben CHM, Spruit MA, Groenen MTJ, Wouters EFM, Janssen DJA. Efficacy of advance care planning: a systematic review and meta-analysis. J Am Med Dir Assoc. 2014;15(7):477–89. Houben CHM, Spruit MA, Groenen MTJ, Wouters EFM, Janssen DJA. Efficacy of advance care planning: a systematic review and meta-analysis. J Am Med Dir Assoc. 2014;15(7):477–89.
17.
go back to reference Tolle SW, Tilden VP, Nelson CA, Dunn PM. A prospective study of the efficacy of the physician order form for life-sustaining treatment. J Am Geriatr Soc. 1998;46(9):1097–102. Tolle SW, Tilden VP, Nelson CA, Dunn PM. A prospective study of the efficacy of the physician order form for life-sustaining treatment. J Am Geriatr Soc. 1998;46(9):1097–102.
18.
go back to reference Happ MB, Capezuti E, Strumpf NE, Wagner L, Cunningham S, Evans L, et al. Advance care planning and end-of-life care for hospitalized nursing home residents. J Am Geriatr Soc. 2002;50(5):829–35. Happ MB, Capezuti E, Strumpf NE, Wagner L, Cunningham S, Evans L, et al. Advance care planning and end-of-life care for hospitalized nursing home residents. J Am Geriatr Soc. 2002;50(5):829–35.
19.
go back to reference Pearlman RA, Starks H, Cain KC, Cole WG. Improvements in advance care planning in the Veterans Affairs System: results of a multifaceted intervention. Arch Intern Med. 2005;165(6):667–74. Pearlman RA, Starks H, Cain KC, Cole WG. Improvements in advance care planning in the Veterans Affairs System: results of a multifaceted intervention. Arch Intern Med. 2005;165(6):667–74.
20.
go back to reference Tamayo-Velázquez MI, Simón-Lorda P, Villegas-Portero R, Higueras-Callejón C, García-Gutiérrez JF, Martínez-Pecino F, et al. Interventions to promote the use of advance directives: an overview of systematic reviews. Patient Educ Couns. 2010;80(1):10–20. Tamayo-Velázquez MI, Simón-Lorda P, Villegas-Portero R, Higueras-Callejón C, García-Gutiérrez JF, Martínez-Pecino F, et al. Interventions to promote the use of advance directives: an overview of systematic reviews. Patient Educ Couns. 2010;80(1):10–20.
21.
go back to reference Emanuel LL, Barry MJ, Stoeckle JD, Ettelson LM, Emanuel EJ, Emanuel LL, et al. Advance directives for medical care — a case for greater use. N Engl J Med. 1991;324(13):889–95. Emanuel LL, Barry MJ, Stoeckle JD, Ettelson LM, Emanuel EJ, Emanuel LL, et al. Advance directives for medical care — a case for greater use. N Engl J Med. 1991;324(13):889–95.
22.
go back to reference Maxfield CL, Pohl JM, Colling K. Advance directives: a guide for patient discussions. Nurse Pract. 2003;28(5):38–41. Maxfield CL, Pohl JM, Colling K. Advance directives: a guide for patient discussions. Nurse Pract. 2003;28(5):38–41.
23.
go back to reference Johnston SC, Pfeifer MP, Mcnutt R. The Discussion About Advance Directives: Patient and Physician Opinions Regarding When and How It Should Be Conducted. Arch Intern Med. 1995;155(10):1025–30. Johnston SC, Pfeifer MP, Mcnutt R. The Discussion About Advance Directives: Patient and Physician Opinions Regarding When and How It Should Be Conducted. Arch Intern Med. 1995;155(10):1025–30.
24.
go back to reference Ramsaroop SD, Reid MC, Adelman RD. Completing an advance directive in the primary care setting: what do we need for success? J Am Geriatr Soc. 2007;55(2):277–83. Ramsaroop SD, Reid MC, Adelman RD. Completing an advance directive in the primary care setting: what do we need for success? J Am Geriatr Soc. 2007;55(2):277–83.
27.
go back to reference Turner L, Shamseer L, Altman DG, Weeks L, Peters J, Kober T, Dias S, Schulz KF, Plint AC, Moher D. Consolidated standards of reporting trials (CONSORT) and the completeness of reporting of randomised controlled trials (RCTs) published in medical journals. Cochrane Database of Systematic Reviews. 2012;(11):1–125, Art. No.: MR000030. https://doi.org/10.1002/14651858.MR000030.pub2. Turner L, Shamseer L, Altman DG, Weeks L, Peters J, Kober T, Dias S, Schulz KF, Plint AC, Moher D. Consolidated standards of reporting trials (CONSORT) and the completeness of reporting of randomised controlled trials (RCTs) published in medical journals. Cochrane Database of Systematic Reviews. 2012;(11):1–125, Art. No.: MR000030. https://​doi.​org/​10.​1002/​14651858.​MR000030.​pub2.
28.
go back to reference Yan S, Kwan YH, Thumboo J, Low LL. Characteristics and Health Care Utilization of Different Segments of a Multiethnic Asian Population in Singapore. JAMA Netw Open. 2019. Yan S, Kwan YH, Thumboo J, Low LL. Characteristics and Health Care Utilization of Different Segments of a Multiethnic Asian Population in Singapore. JAMA Netw Open. 2019.
29.
go back to reference Grimaldo DA, Wiener-Kronish JP, Jurson T, Shaughnessy TE, Curtis JR, Liu LL. A randomized, controlled trial of advance care planning discussions during preoperative evaluations. Anesthesiology. 200195(1):43–50. Grimaldo DA, Wiener-Kronish JP, Jurson T, Shaughnessy TE, Curtis JR, Liu LL. A randomized, controlled trial of advance care planning discussions during preoperative evaluations. Anesthesiology. 200195(1):43–50.
35.
go back to reference Brown JB, Beck A, Boles M, Barrett P. Practical methods to increase use of advance medical directives. J Gen Intern Med. 1999;14(1):21–6. Brown JB, Beck A, Boles M, Barrett P. Practical methods to increase use of advance medical directives. J Gen Intern Med. 1999;14(1):21–6.
36.
go back to reference Sachs GA, Stocking CB, Miles SH. Empowerment of the Older Patient? A Randomized, Controlled Trial To Increase Discussion and Use of Advance Directives. J Am Geriatr Soc. 1992;40:269–73.CrossRef Sachs GA, Stocking CB, Miles SH. Empowerment of the Older Patient? A Randomized, Controlled Trial To Increase Discussion and Use of Advance Directives. J Am Geriatr Soc. 1992;40:269–73.CrossRef
37.
go back to reference Yamada R, Galecki AT, Goold SD, Hogikyan RV. A multimedia intervention on cardiopulmonary resuscitation and advance directives. J Gen Intern Med. 1999;14(9):559–63. Yamada R, Galecki AT, Goold SD, Hogikyan RV. A multimedia intervention on cardiopulmonary resuscitation and advance directives. J Gen Intern Med. 1999;14(9):559–63.
38.
go back to reference Meier DE, Gold G, Mertz K, Taylor B, Cammer-Paris BE, Seckler A, et al. Enhancement of proxy appointment for older persons: Physician counselling in the ambulatory setting. J Am Geriatr Soc. 1996;44(1):37–43. Meier DE, Gold G, Mertz K, Taylor B, Cammer-Paris BE, Seckler A, et al. Enhancement of proxy appointment for older persons: Physician counselling in the ambulatory setting. J Am Geriatr Soc. 1996;44(1):37–43.
39.
go back to reference Luptak MK, Boult C. A method for increasing elders’ use of advance directives. Gerontologist. 1994;34(3):409–12. Luptak MK, Boult C. A method for increasing elders’ use of advance directives. Gerontologist. 1994;34(3):409–12.
40.
go back to reference Dipko LR, Xavier K, Kohlwes RJ. Advance Directive Group Education in a VA Outpatient Clinic. Soc Work Health Care. 2003;38(2):93–106. Dipko LR, Xavier K, Kohlwes RJ. Advance Directive Group Education in a VA Outpatient Clinic. Soc Work Health Care. 2003;38(2):93–106.
41.
go back to reference Paladino J, Fromme EK. Preparing for serious illness: a model for better conversations over the continuum of care. Am Fam Physician. 2019;99(5):281–4. Paladino J, Fromme EK. Preparing for serious illness: a model for better conversations over the continuum of care. Am Fam Physician. 2019;99(5):281–4.
42.
go back to reference Chandar M, Brockstein B, Zunamon A, Silverman I, Dlouhy S, Ashlevitz K, et al. Perspectives of Health-Care Providers Toward Advance Care Planning in Patients With Advanced Cancer and Congestive Heart Failure. Am J Hosp Palliat Med. 2017;34(5):423–9. Chandar M, Brockstein B, Zunamon A, Silverman I, Dlouhy S, Ashlevitz K, et al. Perspectives of Health-Care Providers Toward Advance Care Planning in Patients With Advanced Cancer and Congestive Heart Failure. Am J Hosp Palliat Med. 2017;34(5):423–9.
43.
go back to reference Jones CA, Acevedo J, Bull J, Kamal AH. Top 10 Tips for Using Advance Care Planning Codes in Palliative Medicine and beyond. J Palliat Med. 2016;19(12):1249–53. Jones CA, Acevedo J, Bull J, Kamal AH. Top 10 Tips for Using Advance Care Planning Codes in Palliative Medicine and beyond. J Palliat Med. 2016;19(12):1249–53.
44.
go back to reference Silveira MJ, Kim SYH, Langa KM. Advance Directives and Outcomes of Surrogate Decision Making before Death. N Engl J Med. 2010;362(13):1211–8. Silveira MJ, Kim SYH, Langa KM. Advance Directives and Outcomes of Surrogate Decision Making before Death. N Engl J Med. 2010;362(13):1211–8.
45.
go back to reference Fleuren N, Depla MF, Pasman HRW, Janssen DJ, Onwuteaka-Philipsen PBD, Hertogh PCM, et al. Association between subjective remaining life expectancy and advance care planning in older adults: a cross-sectional study. J Pain Symptom Manage. 2021;00(00):1–11. Fleuren N, Depla MF, Pasman HRW, Janssen DJ, Onwuteaka-Philipsen PBD, Hertogh PCM, et al. Association between subjective remaining life expectancy and advance care planning in older adults: a cross-sectional study. J Pain Symptom Manage. 2021;00(00):1–11.
46.
go back to reference Bernacki R, Hutchings M, Vick J, Smith G, Paladino J, Lipsitz S, et al. Development of the Serious Illness Care Program: a randomised controlled trial of a palliative care communication intervention. BMJ Open. 2015;5:1–14. Bernacki R, Hutchings M, Vick J, Smith G, Paladino J, Lipsitz S, et al. Development of the Serious Illness Care Program: a randomised controlled trial of a palliative care communication intervention. BMJ Open. 2015;5:1–14.
47.
go back to reference Paladino J, Koritsanszky L, Nisotel L, Neville BA, Miller K, Sanders J, et al. Patient and clinician experience of a serious illness conversation guide in oncology: a descriptive analysis. Cancer Med. 2020;9(13):4550–60. Paladino J, Koritsanszky L, Nisotel L, Neville BA, Miller K, Sanders J, et al. Patient and clinician experience of a serious illness conversation guide in oncology: a descriptive analysis. Cancer Med. 2020;9(13):4550–60.
49.
go back to reference Bernard C, Tan A, Slaven M, Elston D, Heyland DK, Howard M. Exploring patient-reported barriers to advance care planning in family practice. BMC Fam Pract. 2020;21:1–9. Bernard C, Tan A, Slaven M, Elston D, Heyland DK, Howard M. Exploring patient-reported barriers to advance care planning in family practice. BMC Fam Pract. 2020;21:1–9.
50.
go back to reference Dhillon K, Jerome D, Teeluck R, Yu Y. Advance care planning in family medicine training. Can Fam Physician. 2018;64(5):394–6. Dhillon K, Jerome D, Teeluck R, Yu Y. Advance care planning in family medicine training. Can Fam Physician. 2018;64(5):394–6.
52.
go back to reference Aitken P V. Incorporating advance care planning into family practice. Am Fam Physician. 1999;59(3):605. Aitken P V. Incorporating advance care planning into family practice. Am Fam Physician. 1999;59(3):605.
53.
go back to reference Hsu CY, O’Connor M, Lee S. Understandings of death and dying for people of Chinese origin. Death Stud. 2009;33:153–74.CrossRef Hsu CY, O’Connor M, Lee S. Understandings of death and dying for people of Chinese origin. Death Stud. 2009;33:153–74.CrossRef
57.
go back to reference Radha Krishna LK, Alsuwaigh R. Understanding the fluid nature of personhood - the ring theory of personhood. Bioethics. 2015;29:171–81.CrossRef Radha Krishna LK, Alsuwaigh R. Understanding the fluid nature of personhood - the ring theory of personhood. Bioethics. 2015;29:171–81.CrossRef
Metadata
Title
Increasing the completion rate of the advance directives in primary care setting – a randomized controlled trial
Authors
Cunzhi Xu
Shi Yan
Jade Chee
Emily Pui-Yan Lee
Han Wei Lim
Sarah Woon Ching Lim
Lian Leng Low
Publication date
01-12-2021
Publisher
BioMed Central
Keywords
Care
Living Will
Published in
BMC Primary Care / Issue 1/2021
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/s12875-021-01473-1

Other articles of this Issue 1/2021

BMC Primary Care 1/2021 Go to the issue