Skip to main content
Top
Published in: BMC Primary Care 1/2016

Open Access 01-12-2016 | Research article

Applying clinical guidelines in general practice: a qualitative study of potential complications

Authors: Bjarne Austad, Irene Hetlevik, Bente Prytz Mjølstad, Anne-Sofie Helvik

Published in: BMC Primary Care | Issue 1/2016

Login to get access

Abstract

Background

Clinical guidelines for single diseases often pose problems in general practice work with multimorbid patients. However, little research focuses on how general practice is affected by the demand to follow multiple guidelines. This study explored Norwegian general practitioners’ (GPs’) experiences with and reflections upon the consequences for general practice of applying multiple guidelines.

Methods

Qualitative focus group study carried out in Mid-Norway. The study involved a purposeful sample of 25 Norwegian GPs from four pre-existing groups. Interviews were audio-recorded, transcribed and analyzed using systematic text condensation, i.e. applying a phenomenological approach.

Results

The GPs’ responses clustered around two major topics: 1) Complications for the GPs of applying multiple guidelines; and, 2) Complications for their patients when GPs apply multiple guidelines. For the GPs, applying multiple guidelines created a highly problematic situation as they felt obliged to implement guidelines that were not suited to their patients: too often, the map and the terrain did not match. They also experienced greater insecurity regarding their own practice which, they admitted, resulted in an increased tendency to practice ‘defensive medicine’. For their patients, the GPs experienced that applying multiple guidelines increased the risk of polypharmacy, excessive non-pharmacological recommendations, a tendency toward medicalization and, for some, a reduction in quality of life.

Conclusions

The GPs experienced negative consequences when obliged to apply a variety of single disease guidelines to multimorbid patients, including increased risk of polypharmacy and overtreatment. We believe patient-centered care and the GPs’ courage to non-comply when necessary may aid in reducing these risks. Health care authorities and guideline developers need to be aware of the potential negative effects of applying a single disease focus in general practice, where multimorbidity is highly prevalent.
Literature
3.
go back to reference Lugtenberg M, Burgers JS, Han D, Westert GP. General practitioners’ preferences for interventions to improve guideline adherence. J Eval Clin Pract. 2014;20(6):820–6.CrossRefPubMed Lugtenberg M, Burgers JS, Han D, Westert GP. General practitioners’ preferences for interventions to improve guideline adherence. J Eval Clin Pract. 2014;20(6):820–6.CrossRefPubMed
4.
go back to reference Blozik E, van den Bussche H, Gurtner F, Schafer I, Scherer M. Epidemiological strategies for adapting clinical practice guidelines to the needs of multimorbid patients. BMC Health Serv Res. 2013;13:352.CrossRefPubMedPubMedCentral Blozik E, van den Bussche H, Gurtner F, Schafer I, Scherer M. Epidemiological strategies for adapting clinical practice guidelines to the needs of multimorbid patients. BMC Health Serv Res. 2013;13:352.CrossRefPubMedPubMedCentral
5.
go back to reference Hughes LD, McMurdo ME, Guthrie B. Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity. Age Ageing. 2013;42(1):62–9.CrossRefPubMed Hughes LD, McMurdo ME, Guthrie B. Guidelines for people not for diseases: the challenges of applying UK clinical guidelines to people with multimorbidity. Age Ageing. 2013;42(1):62–9.CrossRefPubMed
6.
go back to reference Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet. 2012;380(9836):37–43.CrossRefPubMed Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet. 2012;380(9836):37–43.CrossRefPubMed
7.
go back to reference Tomasdottir MO, Getz L, Sigurdsson JA, Petursson H, Kirkengen AL, Krokstad S, McEwen B, Hetlevik I. Co- and multimorbidity patterns in an unselected Norwegian population: cross-sectional analysis based on the HUNT study and theoretical reflections concerning basic medical models. Europ J for Per Centered Health. 2014;2(3):335–45. Tomasdottir MO, Getz L, Sigurdsson JA, Petursson H, Kirkengen AL, Krokstad S, McEwen B, Hetlevik I. Co- and multimorbidity patterns in an unselected Norwegian population: cross-sectional analysis based on the HUNT study and theoretical reflections concerning basic medical models. Europ J for Per Centered Health. 2014;2(3):335–45.
8.
go back to reference Smith S, Soubhi H, Fortin M, Hudon C, O’Dowd T. Managing patients with multimorbidity: systematic review of interventions in primary care and community settings. BMJ. 2012;345:e5205.CrossRefPubMedPubMedCentral Smith S, Soubhi H, Fortin M, Hudon C, O’Dowd T. Managing patients with multimorbidity: systematic review of interventions in primary care and community settings. BMJ. 2012;345:e5205.CrossRefPubMedPubMedCentral
9.
go back to reference Sondergaard E, Willadsen TG, Guassora AD, Vestergaard M, Tomasdottir MO, Borgquist L, Holmberg-Marttila D, Olivarius Nde F, Reventlow S. Problems and challenges in relation to the treatment of patients with multimorbidity: General practitioners’ views and attitudes. Scand J Prim Health Care. 2015;33(2):121–6.CrossRefPubMedPubMedCentral Sondergaard E, Willadsen TG, Guassora AD, Vestergaard M, Tomasdottir MO, Borgquist L, Holmberg-Marttila D, Olivarius Nde F, Reventlow S. Problems and challenges in relation to the treatment of patients with multimorbidity: General practitioners’ views and attitudes. Scand J Prim Health Care. 2015;33(2):121–6.CrossRefPubMedPubMedCentral
10.
go back to reference Ralston SL, Schroeder AR. Doing more vs doing good: Aligning our ethical principles from the personal to the societal. JAMA Pediatr. 2015;169(12):1085–6.CrossRefPubMed Ralston SL, Schroeder AR. Doing more vs doing good: Aligning our ethical principles from the personal to the societal. JAMA Pediatr. 2015;169(12):1085–6.CrossRefPubMed
11.
go back to reference Petursson H, Getz L, Sigurdsson JA, Hetlevik I. Current European guidelines for management of arterial hypertension: are they adequate for use in primary care? Modelling study based on the Norwegian HUNT 2 population. BMC Fam Pract. 2009;10:70.CrossRefPubMedPubMedCentral Petursson H, Getz L, Sigurdsson JA, Hetlevik I. Current European guidelines for management of arterial hypertension: are they adequate for use in primary care? Modelling study based on the Norwegian HUNT 2 population. BMC Fam Pract. 2009;10:70.CrossRefPubMedPubMedCentral
12.
go back to reference Dumbreck S, Flynn A, Nairn M, Wilson M, Treweek S, Mercer SW, Alderson P, Thompson A, Payne K, Guthrie B. Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines. BMJ. 2015;350:h949.CrossRefPubMedPubMedCentral Dumbreck S, Flynn A, Nairn M, Wilson M, Treweek S, Mercer SW, Alderson P, Thompson A, Payne K, Guthrie B. Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines. BMJ. 2015;350:h949.CrossRefPubMedPubMedCentral
13.
go back to reference Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu AW. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA. 2005;294(6):716–24.CrossRefPubMed Boyd CM, Darer J, Boult C, Fried LP, Boult L, Wu AW. Clinical practice guidelines and quality of care for older patients with multiple comorbid diseases: implications for pay for performance. JAMA. 2005;294(6):716–24.CrossRefPubMed
14.
go back to reference Austad B, Hetlevik I, Mjølstad BP, Helvik A-S. General practitioners’ experiences with multiple clinical guidelines: A qualitative study from Norway. Qual Prim Care. 2015;23(2):70–7. Austad B, Hetlevik I, Mjølstad BP, Helvik A-S. General practitioners’ experiences with multiple clinical guidelines: A qualitative study from Norway. Qual Prim Care. 2015;23(2):70–7.
17.
go back to reference Bensing J. Bridging the gap. The separate worlds of evidence-based medicine and patient-centered medicine. Patient Educ Couns. 2000;39(1):17–25.CrossRefPubMed Bensing J. Bridging the gap. The separate worlds of evidence-based medicine and patient-centered medicine. Patient Educ Couns. 2000;39(1):17–25.CrossRefPubMed
18.
go back to reference Vetlesen AJ. Perception, empathy, and judgment: An inquiry into the preconditions of moral performance. PA: Pennsylvania: State University Press: University Park; 1994. Vetlesen AJ. Perception, empathy, and judgment: An inquiry into the preconditions of moral performance. PA: Pennsylvania: State University Press: University Park; 1994.
20.
go back to reference Kvale S. The qualitative research interview: A phenomenological and hermeneutical mode of understanding. Phenomenol Psycol. 1983;14(2):171–96.CrossRef Kvale S. The qualitative research interview: A phenomenological and hermeneutical mode of understanding. Phenomenol Psycol. 1983;14(2):171–96.CrossRef
21.
go back to reference Mishler EG. Research interviewing: context and narrative. Cambridge, MA: Harvard University Press; 1986. Mishler EG. Research interviewing: context and narrative. Cambridge, MA: Harvard University Press; 1986.
22.
go back to reference Fern EF. Advanced Focus Group Research. Thousands Oaks, California: Sage; 2001.CrossRef Fern EF. Advanced Focus Group Research. Thousands Oaks, California: Sage; 2001.CrossRef
23.
go back to reference Garattini L, Gritti S, De Compadri P, Casadei G. Continuing Medical Education in six European countries: a comparative analysis. Health Policy. 2010;94(3):246–54.CrossRefPubMed Garattini L, Gritti S, De Compadri P, Casadei G. Continuing Medical Education in six European countries: a comparative analysis. Health Policy. 2010;94(3):246–54.CrossRefPubMed
25.
go back to reference Malterud K. Systematic text condensation: a strategy for qualitative analysis. Scand J Public Health. 2012;40(8):795–805.CrossRefPubMed Malterud K. Systematic text condensation: a strategy for qualitative analysis. Scand J Public Health. 2012;40(8):795–805.CrossRefPubMed
26.
go back to reference Giorgi A. The descriptive phenomenological method in psychology: a modified Husserlian approach. Pittsburgh, PA: Duquesne University Press; 2009. Giorgi A. The descriptive phenomenological method in psychology: a modified Husserlian approach. Pittsburgh, PA: Duquesne University Press; 2009.
27.
29.
go back to reference Moynihan R, Doust J, Henry D. Preventing overdiagnosis: how to stop harming the healthy. BMJ. 2012;344:e3502.CrossRefPubMed Moynihan R, Doust J, Henry D. Preventing overdiagnosis: how to stop harming the healthy. BMJ. 2012;344:e3502.CrossRefPubMed
34.
go back to reference Carter SM, Rogers W, Heath I, Degeling C, Doust J, Barratt A. The challenge of overdiagnosis begins with its definition. BMJ. 2015;350:h869.CrossRefPubMed Carter SM, Rogers W, Heath I, Degeling C, Doust J, Barratt A. The challenge of overdiagnosis begins with its definition. BMJ. 2015;350:h869.CrossRefPubMed
35.
go back to reference Hoffmann TC, Del Mar C. Patients’ expectations of the benefits and harms of treatments, screening, and tests: a systematic review. JAMA Internal Med. 2015;175(2):274–86.CrossRef Hoffmann TC, Del Mar C. Patients’ expectations of the benefits and harms of treatments, screening, and tests: a systematic review. JAMA Internal Med. 2015;175(2):274–86.CrossRef
36.
go back to reference Moynihan R, Henry D, Moons KG. Using evidence to combat overdiagnosis and overtreatment: evaluating treatments, tests, and disease definitions in the time of too much. PLoS Med. 2014;11(7):e1001655.CrossRefPubMedPubMedCentral Moynihan R, Henry D, Moons KG. Using evidence to combat overdiagnosis and overtreatment: evaluating treatments, tests, and disease definitions in the time of too much. PLoS Med. 2014;11(7):e1001655.CrossRefPubMedPubMedCentral
38.
go back to reference Moynihan RN, Cooke GP, Doust JA, Bero L, Hill S, Glasziou PP. Expanding disease definitions in guidelines and expert panel ties to industry: a cross-sectional study of common conditions in the United States. PLoS Med. 2013;10(8):e1001500.CrossRefPubMedPubMedCentral Moynihan RN, Cooke GP, Doust JA, Bero L, Hill S, Glasziou PP. Expanding disease definitions in guidelines and expert panel ties to industry: a cross-sectional study of common conditions in the United States. PLoS Med. 2013;10(8):e1001500.CrossRefPubMedPubMedCentral
40.
41.
go back to reference Payne RA, Abel GA, Avery AJ, Mercer SW, Roland MO. Is polypharmacy always hazardous? A retrospective cohort analysis using linked electronic health records from primary and secondary care. Br J Clin Pharmacol. 2014;77(6):1073–82.CrossRefPubMedPubMedCentral Payne RA, Abel GA, Avery AJ, Mercer SW, Roland MO. Is polypharmacy always hazardous? A retrospective cohort analysis using linked electronic health records from primary and secondary care. Br J Clin Pharmacol. 2014;77(6):1073–82.CrossRefPubMedPubMedCentral
42.
43.
go back to reference Uhlig K, Leff B, Kent D, Dy S, Brunnhuber K, Burgers JS, Greenfield S, Guyatt G, High K, Leipzig R, et al. A framework for crafting clinical practice guidelines that are relevant to the care and management of people with multimorbidity. J Gen Intern Med. 2014;29(4):670–9.CrossRefPubMedPubMedCentral Uhlig K, Leff B, Kent D, Dy S, Brunnhuber K, Burgers JS, Greenfield S, Guyatt G, High K, Leipzig R, et al. A framework for crafting clinical practice guidelines that are relevant to the care and management of people with multimorbidity. J Gen Intern Med. 2014;29(4):670–9.CrossRefPubMedPubMedCentral
44.
go back to reference Coventry P, Lovell K, Dickens C, Bower P, Chew-Graham C, McElvenny D. Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease. BMJ. 2015;350:h638.CrossRefPubMedPubMedCentral Coventry P, Lovell K, Dickens C, Bower P, Chew-Graham C, McElvenny D. Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease. BMJ. 2015;350:h638.CrossRefPubMedPubMedCentral
45.
go back to reference Cottrell E, Yardley S. Lived experiences of multimorbidity: An interpretative meta-synthesis of patients’, general practitioners’ and trainees’ perceptions. Chronic Illn. 2015;11(4):279–303.CrossRefPubMed Cottrell E, Yardley S. Lived experiences of multimorbidity: An interpretative meta-synthesis of patients’, general practitioners’ and trainees’ perceptions. Chronic Illn. 2015;11(4):279–303.CrossRefPubMed
46.
go back to reference Rosstad T, Garasen H, Steinsbekk A, Sletvold O, Grimsmo A. Development of a patient-centred care pathway across healthcare providers: a qualitative study. BMC Health Serv Res. 2013;13:121.CrossRefPubMedPubMedCentral Rosstad T, Garasen H, Steinsbekk A, Sletvold O, Grimsmo A. Development of a patient-centred care pathway across healthcare providers: a qualitative study. BMC Health Serv Res. 2013;13:121.CrossRefPubMedPubMedCentral
48.
go back to reference Steel N, Abdelhamid A, Stokes T, Edwards H, Fleetcroft R, Howe A, Qureshi N. A review of clinical practice guidelines found that they were often based on evidence of uncertain relevance to primary care patients. J Clin Epidemiol. 2014;67(11):1251–7.CrossRefPubMedPubMedCentral Steel N, Abdelhamid A, Stokes T, Edwards H, Fleetcroft R, Howe A, Qureshi N. A review of clinical practice guidelines found that they were often based on evidence of uncertain relevance to primary care patients. J Clin Epidemiol. 2014;67(11):1251–7.CrossRefPubMedPubMedCentral
50.
go back to reference Hetlevik I, Getz L, Kirkengen AL. General practitioners who do not follow practice guidelines--may they have reasons not to? Tidsskr Nor Laegeforen. 2008;128(19):2218–20.PubMed Hetlevik I, Getz L, Kirkengen AL. General practitioners who do not follow practice guidelines--may they have reasons not to? Tidsskr Nor Laegeforen. 2008;128(19):2218–20.PubMed
51.
go back to reference Kirkengen AL, Ekeland TJ, Getz L, Hetlevik I, Schei E, Ulvestad E, Vetlesen AJ. Medicine’s perception of reality - a split picture: critical reflections on apparent anomalies within the biomedical theory of science. J Eval Clin Practice. 2015. doi: 10.1111/jep.12369. Kirkengen AL, Ekeland TJ, Getz L, Hetlevik I, Schei E, Ulvestad E, Vetlesen AJ. Medicine’s perception of reality - a split picture: critical reflections on apparent anomalies within the biomedical theory of science. J Eval Clin Practice. 2015. doi: 10.​1111/​jep.​12369.
52.
go back to reference Sinnott C, Hugh SM, Boyce MB, Bradley CP. What to give the patient who has everything? A qualitative study of prescribing for multimorbidity in primary care. Br J Gen Pract. 2015;65(632):e184–91.CrossRefPubMedPubMedCentral Sinnott C, Hugh SM, Boyce MB, Bradley CP. What to give the patient who has everything? A qualitative study of prescribing for multimorbidity in primary care. Br J Gen Pract. 2015;65(632):e184–91.CrossRefPubMedPubMedCentral
54.
go back to reference Starfield B. Primary Care: Balancing Health Needs, Services, and Technology. New York: Oxford University Press; 1998. Starfield B. Primary Care: Balancing Health Needs, Services, and Technology. New York: Oxford University Press; 1998.
Metadata
Title
Applying clinical guidelines in general practice: a qualitative study of potential complications
Authors
Bjarne Austad
Irene Hetlevik
Bente Prytz Mjølstad
Anne-Sofie Helvik
Publication date
01-12-2016
Publisher
BioMed Central
Published in
BMC Primary Care / Issue 1/2016
Electronic ISSN: 2731-4553
DOI
https://doi.org/10.1186/s12875-016-0490-3

Other articles of this Issue 1/2016

BMC Primary Care 1/2016 Go to the issue