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Open Access 01-12-2024 | Morphine | Case Report

Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain

Authors: Qing Li, Yan-ling Long, Yun-wu He, Hui Long, Zhen-ping Xiao, Yong-lin Li, Wu-zhou Yang, Li-ping Jiang, Wei Gao, Cong Zou

Published in: BMC Anesthesiology | Issue 1/2024

Abstract

Background

Extensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics.

Case Presentation

The present study reports a case of an extensive metastatic esophageal cancer patient with severe intractable pain, who underwent translumbar subarachnoid puncture with intrathecal catheterization to the prepontine cistern. After continuous infusion of low-dose morphine, the pain was well-controlled with a decrease in the numeric rating scale (NRS) of pain score from 9 to 0, and the few adverse reactions to the treatment disappeared at a low dose of morphine.

Conclusions

The patient achieved a good quality of life during the one-month follow-up period.

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Title: Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain
Authors: Qing Li
Yan-ling Long
Yun-wu He
Hui Long
Zhen-ping Xiao
Yong-lin Li
Wu-zhou Yang
Li-ping Jiang
Wei Gao
Cong Zou
Publication date: 01-12-2024
Publisher: BioMed Central
Keywords: Morphine
Opioids
Opioids
Published in: BMC Anesthesiology / Issue 1/2024
Electronic ISSN: 1471-2253
DOI: https://doi.org/10.1186/s12871-024-02426-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain

Abstract

Background

Case Presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case Presentation

Conclusions

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