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Published in: The Journal of Headache and Pain 1/2015

Open Access 01-12-2015 | Research article

Tension-type headache associated with obstructive sleep apnea: a nationwide population-based study

Authors: Yu-Chwen Chiu, Hsiao-Yun Hu, Fei-Peng Lee, Hung-Meng Huang

Published in: The Journal of Headache and Pain | Issue 1/2015

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Abstract

Background

There is still controversy regarding the association between primary headaches and obstructive sleep apnea. We explored the relationship between tension-type headache (TTH) and obstructive sleep apnea (OSA) using a large nationwide population-based data set in Taiwan.

Methods

We identified 4759 patients diagnosed with OSA from the Taiwan Longitudinal Health Insurance Database, based on polysomnography, as the OSA group. We then randomly selected 19036 subjects without OSA, matched by sex and age, to serve as the non-OSA group. The multivariate Cox proportional hazards model with matching for age and sex was used to assess the possible associations between TTH and OSA among the patients.

Results

The prevalence of TTH was 10.2% among OSA patients and 7.7% among non-OSA patients (p < 0.001). The multivariate Cox proportional hazards model revealed patients with OSA were more likely to have TTH (hazard ratio, 1.18; 95% CI, 1.06–1.31) (p = 0.003) than patients in the non-OSA group.

Conclusion

Patients with OSA had a higher likelihood of developing TTH than patients in the non-OSA group. Further studies of physiological patterns between OSA and TTH are needed to confirm the study findings.
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Metadata
Title
Tension-type headache associated with obstructive sleep apnea: a nationwide population-based study
Authors
Yu-Chwen Chiu
Hsiao-Yun Hu
Fei-Peng Lee
Hung-Meng Huang
Publication date
01-12-2015
Publisher
Springer Milan
Published in
The Journal of Headache and Pain / Issue 1/2015
Print ISSN: 1129-2369
Electronic ISSN: 1129-2377
DOI
https://doi.org/10.1186/s10194-015-0517-5

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