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Open Access 01-02-2011 | Poster presentation

Influence of body mass index on the innate immune response during human endotoxemia

Author: R Van der Pluijm

Published in: Critical Care | Special Issue 1/2011

Excerpt

Accumulating data suggest a protective effect of obesity in the case of severe infections. Higher baseline levels of the proinflammatory cytokine TNFα as well as more pronounced TNFα release following whole blood stimulation with endotoxin are reported in patients with a higher body mass index (BMI). This more pronounced proinflammatory response in obese patients may enable a rapid and more effective clearance of microbial pathogens. The effect of the body mass index on the innate immune response in vivo has not been assessed. …

Title: Influence of body mass index on the innate immune response during human endotoxemia
Author: R Van der Pluijm
Publication date: 01-02-2011
Publisher: BioMed Central
Published in: Critical Care / Issue Special Issue 1/2011
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc9667

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Influence of body mass index on the innate immune response during human endotoxemia

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Keynote webinar | Spotlight on medication adherence

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