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Published in: Critical Care 6/2000

01-12-2000 | Review

Continuous haemofiltration in the intensive care unit

Authors: Rinaldo Bellomo, Claudio Ronco

Published in: Critical Care | Issue 6/2000

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Abstract

Continuous renal replacement therapy (CRRT) was first described in 1977 for the treatment of diuretic-unresponsive fluid overload in the intensive care unit (ICU). Since that time this treatment has undergone a remarkable technical and conceptual evolution. It is now available in most tertiary ICUs around the world and has almost completely replaced intermittent haemodialysis (IHD) in some countries. Specially made machines are now available, and venovenous therapies that use blood pumps have replaced simpler techniques. Although, it remains controversial whether CRRT decreases mortality when compared with IHD, much evidence suggests that it is physiologically superior. The use of CRRT has also spurred renewed interest in the broader concept of blood purification, particularly in septic states. Experimental evidence suggests that this is a promising approach to the management of septic shock in critically ill patients. The evolution and use of CRRT is likely to continue and grow over the next decade.
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Metadata
Title
Continuous haemofiltration in the intensive care unit
Authors
Rinaldo Bellomo
Claudio Ronco
Publication date
01-12-2000
Publisher
BioMed Central
Published in
Critical Care / Issue 6/2000
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc718

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