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Published in: Critical Care 3/2008

01-06-2008 | Commentary

Moving beyond tight glucose control to safe effective glucose control

Authors: James S Krinsley, Jean-Charles Preiser

Published in: Critical Care | Issue 3/2008

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Abstract

The impressive benefits related to the use of tight glucose control by intensive insulin therapy have not been reproduced until now in multicenter large-scale prospective randomized trials. Although the reasons for these failures are not entirely clear, we suggest the use of a stepwise approach – Safe, Effective Glucose Control – that will essentially target an intermediate blood glucose level. As compared with genuine tight glucose control, Safe, Effective Glucose Control – already used in many intensive care units worldwide – is intended to decrease the rate of hypoglycemia and the workload, while reducing the adverse effects of severe hyperglycemia.
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Metadata
Title
Moving beyond tight glucose control to safe effective glucose control
Authors
James S Krinsley
Jean-Charles Preiser
Publication date
01-06-2008
Publisher
BioMed Central
Published in
Critical Care / Issue 3/2008
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc6889

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