Skip to main content
Top
Published in: Critical Care 2/2008

Open Access 01-04-2008 | Research

Effect of a heated humidifier during continuous positive airway pressure delivered by a helmet

Authors: Davide Chiumello, Monica Chierichetti, Federica Tallarini, Paola Cozzi, Massimo Cressoni, Federico Polli, Riccardo Colombo, Antonio Castelli, Luciano Gattinoni

Published in: Critical Care | Issue 2/2008

Login to get access

Abstract

Introduction

The helmet may be an effective interface for the delivery of noninvasive positive pressure ventilation. The high internal gas volume of the helmet can act as a 'mixing chamber', in which the humidity of the patient's expired alveolar gases increases the humidity of the dry medical gases, thus avoiding the need for active humidification. We evaluated the temperature and humidity of respiratory gases inside the helmet, with and without a heated humidifier, during continuous positive airway pressure (CPAP) delivered with a helmet.

Methods

Nine patients with acute respiratory failure (arterial oxygen tension/fractional inspired oxygen ratio 209 ± 52 mmHg) and 10 healthy individuals were subjected to CPAP. The CPAP was delivered either through a mechanical ventilator or by continuous low (40 l/min) or high flow (80 l/min). Humidity was measured inside the helmet using a capacitive hygrometer. The level of patient comfort was evaluated using a continuous scale.

Results

In patients with acute respiratory failure, the heated humidifier significantly increased the absolute humidity from 18.4 ± 5.5 mgH2O/l to 34.1 ± 2.8 mgH2O/l during ventilator CPAP, from 11.4 ± 4.8 mgH2O/l to 33.9 ± 1.9 mgH2O/l during continuous low-flow CPAP, and from 6.4 ± 1.8 mgH2O/l to 24.2 ± 5.4 mgH2O/l during continuous high-flow CPAP. Without the heated humidifier, the absolute humidity was significantly higher with ventilator CPAP than with continuous low-flow and high-flow CPAP. The level of comfort was similar for all the three modes of ventilation and with or without the heated humidifier. The findings in healthy individuals were similar to those in the patients with acute respiratory failure.

Conclusion

The fresh gas flowing through the helmet with continuous flow CPAP systems limited the possibility to increase the humidity. We suggest that a heated humidifier should be employed with continuous flow CPAP systems.
Appendix
Available only for authorised users
Literature
1.
go back to reference Shelly MP, Lloyd GM, Park GR: A review of the mechanisms and methods of humidification of inspired gases. Intensive Care Med 1988, 14: 1-9. 10.1007/BF00254114PubMedCrossRef Shelly MP, Lloyd GM, Park GR: A review of the mechanisms and methods of humidification of inspired gases. Intensive Care Med 1988, 14: 1-9. 10.1007/BF00254114PubMedCrossRef
2.
go back to reference Chiumello D, Gattinoni L, Pelosi P: Conditioning of inspired gases in mechanically ventilated patients. In Yearbook of Intensive Care and Emergency Medicine. Edited by: Vincent JL. Berlin: Springer-Verlag; 2002:275-86. Chiumello D, Gattinoni L, Pelosi P: Conditioning of inspired gases in mechanically ventilated patients. In Yearbook of Intensive Care and Emergency Medicine. Edited by: Vincent JL. Berlin: Springer-Verlag; 2002:275-86.
3.
go back to reference Chalon J, Loew DA, Malebranche J: Effects of dry anesthetic gases on tracheobronchial ciliated epithelium. Anesthesiology 1972, 37: 338-343. 10.1097/00000542-197211000-00023PubMedCrossRef Chalon J, Loew DA, Malebranche J: Effects of dry anesthetic gases on tracheobronchial ciliated epithelium. Anesthesiology 1972, 37: 338-343. 10.1097/00000542-197211000-00023PubMedCrossRef
4.
go back to reference Noguchi H, Takumi Y, Aochi O: A study of humidification in tracheostomized dogs. Br J Anaesth 1973, 45: 844-848. 10.1093/bja/45.8.844PubMedCrossRef Noguchi H, Takumi Y, Aochi O: A study of humidification in tracheostomized dogs. Br J Anaesth 1973, 45: 844-848. 10.1093/bja/45.8.844PubMedCrossRef
5.
go back to reference Rashad K, Wilson K, Hurt HH Jr, Graff TD, Benson DW: Effect of humidification of anesthetic gases on static compliance. Anesth Analg 1967, 46: 127-133.PubMed Rashad K, Wilson K, Hurt HH Jr, Graff TD, Benson DW: Effect of humidification of anesthetic gases on static compliance. Anesth Analg 1967, 46: 127-133.PubMed
6.
go back to reference Tsuda T, Noguchi H, Takumi Y, Aochi O: Optimum humidification of air administered to a tracheostomy in dogs. Scanning electron microscopy and surfactant studies. Br J Anaesth 1977, 49: 965-977. 10.1093/bja/49.10.965PubMedCrossRef Tsuda T, Noguchi H, Takumi Y, Aochi O: Optimum humidification of air administered to a tracheostomy in dogs. Scanning electron microscopy and surfactant studies. Br J Anaesth 1977, 49: 965-977. 10.1093/bja/49.10.965PubMedCrossRef
7.
go back to reference Anonymous: International Consensus Conferences in Intensive Care Medicine: noninvasive positive pressure ventilation in acute Respiratory failure. Am J Respir Crit Care Med 2001, 163: 283-291.CrossRef Anonymous: International Consensus Conferences in Intensive Care Medicine: noninvasive positive pressure ventilation in acute Respiratory failure. Am J Respir Crit Care Med 2001, 163: 283-291.CrossRef
8.
go back to reference Mador MJ, Krauza M, Pervez A, Pierce D, Braun M: Effect of heated humidification on compliance and quality of life in patients with sleep apnea using nasal continuous positive airway pressure. Chest 2005, 128: 2151-2158. 10.1378/chest.128.4.2151PubMedCrossRef Mador MJ, Krauza M, Pervez A, Pierce D, Braun M: Effect of heated humidification on compliance and quality of life in patients with sleep apnea using nasal continuous positive airway pressure. Chest 2005, 128: 2151-2158. 10.1378/chest.128.4.2151PubMedCrossRef
9.
go back to reference Pepin JL, Leger P, Veale D, Langevin B, Robert D, Levy P: Side effects of nasal continuous positive airway pressure in sleep apnea syndrome. Study of 193 patients in two French sleep centers. Chest 1995, 107: 375-381. 10.1378/chest.107.2.375PubMedCrossRef Pepin JL, Leger P, Veale D, Langevin B, Robert D, Levy P: Side effects of nasal continuous positive airway pressure in sleep apnea syndrome. Study of 193 patients in two French sleep centers. Chest 1995, 107: 375-381. 10.1378/chest.107.2.375PubMedCrossRef
10.
go back to reference Togias AG, Naclerio RM, Proud D, Fish JE, Adkinson NF Jr, Kagey-Sobotka A, et al.: Nasal challenge with cold, dry air results in release of inflammatory mediators. Possible mast cell involvement. J Clin Invest 1985, 76: 1375-1381. 10.1172/JCI112113PubMedPubMedCentralCrossRef Togias AG, Naclerio RM, Proud D, Fish JE, Adkinson NF Jr, Kagey-Sobotka A, et al.: Nasal challenge with cold, dry air results in release of inflammatory mediators. Possible mast cell involvement. J Clin Invest 1985, 76: 1375-1381. 10.1172/JCI112113PubMedPubMedCentralCrossRef
11.
go back to reference Togias AG, Naclerio RM, Peters SP, Nimmagadda I, Proud D, Kagey-Sobotka A, et al.: Local generation of sulfidopeptide leukotrienes upon nasal provocation with cold, dry air. Am Rev Respir Dis 1986, 133: 1133-1137.PubMed Togias AG, Naclerio RM, Peters SP, Nimmagadda I, Proud D, Kagey-Sobotka A, et al.: Local generation of sulfidopeptide leukotrienes upon nasal provocation with cold, dry air. Am Rev Respir Dis 1986, 133: 1133-1137.PubMed
12.
go back to reference Hayes MJ, McGregor FB, Roberts DN, Schroter RC, Pride NB: Continuous nasal positive airway pressure with a mouth leak: effect on nasal mucosal blood flux and nasal geometry. Thorax 1995, 50: 1179-1182.PubMedPubMedCentralCrossRef Hayes MJ, McGregor FB, Roberts DN, Schroter RC, Pride NB: Continuous nasal positive airway pressure with a mouth leak: effect on nasal mucosal blood flux and nasal geometry. Thorax 1995, 50: 1179-1182.PubMedPubMedCentralCrossRef
13.
go back to reference Richards GN, Cistulli PA, Ungar RG, Berthon-Jones M, Sullivan CE: Mouth leak with nasal continuous positive airway pressure increases nasal airway resistance. Am J Respir Crit Care Med 1996, 154: 182-186.PubMedCrossRef Richards GN, Cistulli PA, Ungar RG, Berthon-Jones M, Sullivan CE: Mouth leak with nasal continuous positive airway pressure increases nasal airway resistance. Am J Respir Crit Care Med 1996, 154: 182-186.PubMedCrossRef
14.
go back to reference Massie CA, Hart RW, Peralez K, Richards GN: Effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure. Chest 1999, 116: 403-408. 10.1378/chest.116.2.403PubMedCrossRef Massie CA, Hart RW, Peralez K, Richards GN: Effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure. Chest 1999, 116: 403-408. 10.1378/chest.116.2.403PubMedCrossRef
15.
go back to reference Kallstrom TJ: AARC Clinical Practice Guideline: oxygen therapy for adults in the acute care facility: 2002 revision & update. Respir Care 2002, 47: 717-720.PubMed Kallstrom TJ: AARC Clinical Practice Guideline: oxygen therapy for adults in the acute care facility: 2002 revision & update. Respir Care 2002, 47: 717-720.PubMed
16.
go back to reference Martins De Araujo MT, Vieira SB, Vasquez EC, Fleury B: Heated humidification or face mask to prevent upper airway dryness during continuous positive airway pressure therapy. Chest 2000, 117: 142-147. 10.1378/chest.117.1.142PubMedCrossRef Martins De Araujo MT, Vieira SB, Vasquez EC, Fleury B: Heated humidification or face mask to prevent upper airway dryness during continuous positive airway pressure therapy. Chest 2000, 117: 142-147. 10.1378/chest.117.1.142PubMedCrossRef
17.
go back to reference Rakotonanahary D, Pelletier-Fleury N, Gagnadoux F, Fleury B: Predictive factors for the need for additional humidification during nasal continuous positive airway pressure therapy. Chest 2001, 119: 460-465. 10.1378/chest.119.2.460PubMedCrossRef Rakotonanahary D, Pelletier-Fleury N, Gagnadoux F, Fleury B: Predictive factors for the need for additional humidification during nasal continuous positive airway pressure therapy. Chest 2001, 119: 460-465. 10.1378/chest.119.2.460PubMedCrossRef
18.
go back to reference Schonhofer B, Sortor-Leger S: Equipment needs for noninvasive mechanical ventilation. Eur Respir J 2002, 20: 1029-1036. 10.1183/09031936.02.00404202PubMedCrossRef Schonhofer B, Sortor-Leger S: Equipment needs for noninvasive mechanical ventilation. Eur Respir J 2002, 20: 1029-1036. 10.1183/09031936.02.00404202PubMedCrossRef
19.
go back to reference Wood KE, Flaten AL, Backes WJ: Inspissated secretions: a life-threatening complication of prolonged noninvasive ventilation. Respir Care 2000, 45: 491-493.PubMed Wood KE, Flaten AL, Backes WJ: Inspissated secretions: a life-threatening complication of prolonged noninvasive ventilation. Respir Care 2000, 45: 491-493.PubMed
20.
21.
go back to reference American National Standards Institute: Standard for Humidifiers and Nebulizers for Medical Use. ANSI Z79[9]. Washington, DC: American National Standards Institute; 1979. American National Standards Institute: Standard for Humidifiers and Nebulizers for Medical Use. ANSI Z79[9]. Washington, DC: American National Standards Institute; 1979.
22.
go back to reference Antonelli M, Conti G, Pelosi P, Gregoretti C, Pennisi MA, Costa R, Severgnini P, Chiaranda M, Proietti R: New treatment of acute hypoxemic respiratory failure: noninvasive pressure support ventilation delivered by helmet: a pilot controlled trial. Crit Care Med 2002, 30: 602-608. 10.1097/00003246-200203000-00019PubMedCrossRef Antonelli M, Conti G, Pelosi P, Gregoretti C, Pennisi MA, Costa R, Severgnini P, Chiaranda M, Proietti R: New treatment of acute hypoxemic respiratory failure: noninvasive pressure support ventilation delivered by helmet: a pilot controlled trial. Crit Care Med 2002, 30: 602-608. 10.1097/00003246-200203000-00019PubMedCrossRef
23.
go back to reference Antonelli M, Pennisi MA, Pelosi P, Gregoretti C, Squadrone V, Rocco M, Cecchini L, Chiumello D, Severgnini P, Proietti R, Navalesi P, Conti G: Noninvasive positive pressure ventilation using a helmet in patients with acute exacerbation of chronic obstructive pulmonary disease: a feasibility study. Anesthesiology 2004, 100: 16-24. 10.1097/00000542-200401000-00007PubMedCrossRef Antonelli M, Pennisi MA, Pelosi P, Gregoretti C, Squadrone V, Rocco M, Cecchini L, Chiumello D, Severgnini P, Proietti R, Navalesi P, Conti G: Noninvasive positive pressure ventilation using a helmet in patients with acute exacerbation of chronic obstructive pulmonary disease: a feasibility study. Anesthesiology 2004, 100: 16-24. 10.1097/00000542-200401000-00007PubMedCrossRef
24.
go back to reference Chiumello D, Pelosi P, Carlesso E, Severgnini P, Aspesi M, Gamberoni C, Antonelli M, Conti G, Chiaranda M, Gattinoni L: Noninvasive positive pressure ventilation delivered by helmet vs. standard face mask. Intensive Care Med 2003, 29: 1671-1679. 10.1007/s00134-003-1825-9PubMedCrossRef Chiumello D, Pelosi P, Carlesso E, Severgnini P, Aspesi M, Gamberoni C, Antonelli M, Conti G, Chiaranda M, Gattinoni L: Noninvasive positive pressure ventilation delivered by helmet vs. standard face mask. Intensive Care Med 2003, 29: 1671-1679. 10.1007/s00134-003-1825-9PubMedCrossRef
25.
go back to reference Taccone P, Hess D, Caironi P, Bigatello LM: Continuous positive airway pressure delivered with a 'helmet': effects on carbon dioxide rebreathing. Crit Care Med 2004, 32: 2090-2096. 10.1097/01.CCM.0000142577.63316.C0PubMedCrossRef Taccone P, Hess D, Caironi P, Bigatello LM: Continuous positive airway pressure delivered with a 'helmet': effects on carbon dioxide rebreathing. Crit Care Med 2004, 32: 2090-2096. 10.1097/01.CCM.0000142577.63316.C0PubMedCrossRef
26.
go back to reference Graff TD: Humidification: indications and hazards in respiratory therapy. Anesth Analg 1975, 54: 444-448.PubMedCrossRef Graff TD: Humidification: indications and hazards in respiratory therapy. Anesth Analg 1975, 54: 444-448.PubMedCrossRef
27.
go back to reference Green ID, Nasarajah MS: Water vapor pressure of end-tidal air of normals and chronic bronchitics. J Appl Physiol 1968, 24: 229-231.PubMed Green ID, Nasarajah MS: Water vapor pressure of end-tidal air of normals and chronic bronchitics. J Appl Physiol 1968, 24: 229-231.PubMed
28.
go back to reference Walker JE, Wells RE Jr, Merrill EW: Heat and water exchange in the respiratory tract. Am J Med 1961, 30: 259-267. 10.1016/0002-9343(61)90097-3PubMedCrossRef Walker JE, Wells RE Jr, Merrill EW: Heat and water exchange in the respiratory tract. Am J Med 1961, 30: 259-267. 10.1016/0002-9343(61)90097-3PubMedCrossRef
29.
go back to reference Pelosi P, Chiumello D, Calvi E, Taccone P, Bottino N, Panigada M, Cadringher P, Gattinoni L: Effects of different continuous positive airway pressure devices and periodic hyperinflations on respiratory function. Crit Care Med 2001, 29: 1683-1689. 10.1097/00003246-200109000-00005PubMedCrossRef Pelosi P, Chiumello D, Calvi E, Taccone P, Bottino N, Panigada M, Cadringher P, Gattinoni L: Effects of different continuous positive airway pressure devices and periodic hyperinflations on respiratory function. Crit Care Med 2001, 29: 1683-1689. 10.1097/00003246-200109000-00005PubMedCrossRef
30.
go back to reference Lellouche F, Taillé S, Maggiore SM, Qader S, L'her E, Deye N, Brochard L: Influence of ambient and ventilator output temperatures on performance of heated-wire humidifiers. Am J Respir Crit Care Med 2004, 170: 1073-1079. 10.1164/rccm.200309-1245OCPubMedCrossRef Lellouche F, Taillé S, Maggiore SM, Qader S, L'her E, Deye N, Brochard L: Influence of ambient and ventilator output temperatures on performance of heated-wire humidifiers. Am J Respir Crit Care Med 2004, 170: 1073-1079. 10.1164/rccm.200309-1245OCPubMedCrossRef
31.
go back to reference McFadden ER Jr, Pichurko BM, Bowman HF, Ingenito E, Burns S, Dowling N, Solway J: Thermal mapping of the airways in humans. J Appl Physiol 1985, 58: 564-570. 10.1063/1.335663PubMedCrossRef McFadden ER Jr, Pichurko BM, Bowman HF, Ingenito E, Burns S, Dowling N, Solway J: Thermal mapping of the airways in humans. J Appl Physiol 1985, 58: 564-570. 10.1063/1.335663PubMedCrossRef
32.
go back to reference Williams R, Rankin N, Smith T, Galler D, Seakins P: Relationship between the humidity and temperature of inspired gas and the function of the airway mucosa. Crit Care Med 1996, 24: 1920-1929. 10.1097/00003246-199611000-00025PubMedCrossRef Williams R, Rankin N, Smith T, Galler D, Seakins P: Relationship between the humidity and temperature of inspired gas and the function of the airway mucosa. Crit Care Med 1996, 24: 1920-1929. 10.1097/00003246-199611000-00025PubMedCrossRef
33.
go back to reference Primiano FP Jr, Saidel GM, Montague FW Jr, Kruse KL, Green CG, Horowitz JG: Water vapour and temperature dynamics in the upper airways of normal and CF subjects. Eur Respir J 1988, 1: 407-414.PubMed Primiano FP Jr, Saidel GM, Montague FW Jr, Kruse KL, Green CG, Horowitz JG: Water vapour and temperature dynamics in the upper airways of normal and CF subjects. Eur Respir J 1988, 1: 407-414.PubMed
34.
go back to reference Chatburn RL, Primiano FP Jr: A rational basis for Humidity Terapy. Respir Care 1987, 32: 249-253. Chatburn RL, Primiano FP Jr: A rational basis for Humidity Terapy. Respir Care 1987, 32: 249-253.
35.
go back to reference Randerath WJ, Meier J, Genger H, Domanski U, Ruhle KH: Efficiency of cold passover and heated humidification under continuous positive airway pressure. Eur Respir J 2002, 20: 183-186. 10.1183/09031936.02.00267902PubMedCrossRef Randerath WJ, Meier J, Genger H, Domanski U, Ruhle KH: Efficiency of cold passover and heated humidification under continuous positive airway pressure. Eur Respir J 2002, 20: 183-186. 10.1183/09031936.02.00267902PubMedCrossRef
36.
go back to reference Pelosi P, Chiumello D, Severgnini P, De Grandis CE, Landi L, Chierichetti LM, Frigerio A, Munaro M, Park G, Chiaranda M: Performance of heated wire humidifiers: an in vitro study. J Crit Care 2007, 22: 258-264. 10.1016/j.jcrc.2006.12.009PubMedCrossRef Pelosi P, Chiumello D, Severgnini P, De Grandis CE, Landi L, Chierichetti LM, Frigerio A, Munaro M, Park G, Chiaranda M: Performance of heated wire humidifiers: an in vitro study. J Crit Care 2007, 22: 258-264. 10.1016/j.jcrc.2006.12.009PubMedCrossRef
Metadata
Title
Effect of a heated humidifier during continuous positive airway pressure delivered by a helmet
Authors
Davide Chiumello
Monica Chierichetti
Federica Tallarini
Paola Cozzi
Massimo Cressoni
Federico Polli
Riccardo Colombo
Antonio Castelli
Luciano Gattinoni
Publication date
01-04-2008
Publisher
BioMed Central
Published in
Critical Care / Issue 2/2008
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc6875

Other articles of this Issue 2/2008

Critical Care 2/2008 Go to the issue