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Published in: Critical Care 4/2007

01-08-2007 | Poster presentation

Selective V1a receptor agonists in experimental septic shock

Author: Daniel Traber

Published in: Critical Care | Special Issue 4/2007

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Excerpt

Septic shock is caused by hypotension secondary to vasodilation. This hypotension is resistant to fluid resuscitation and requires the use of vasopressor agents. Recently, it was shown that it may be due to a deficiency in the vasopressor hormone arginine–vasopressin (AVP), a mixed V1a/V2 receptor agonist, leading to the clinical use of AVP in septic shock. We tested the hypothesis that the selective V1a receptor agonist FE 202158 is at least as effective as AVP in a sheep model of pneumonia-induced septic shock. …
Metadata
Title
Selective V1a receptor agonists in experimental septic shock
Author
Daniel Traber
Publication date
01-08-2007
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 4/2007
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc6030

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