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Critical Care
Published in: Critical Care 4/2005

01-08-2005 | Introduction

Re-establishing organ function in severe sepsis: targeting the microcirculation

Author: Jean-François Dhainaut

Published in: Critical Care | Special Issue 4/2005

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Excerpt

Severe sepsis is defined as sepsis associated with acute organ dysfunction, and is a major cause of mortality in critical care patients. More than 750,000 cases of severe sepsis occur annually in the USA, and the syndrome causes 215,000 deaths in the USA every year [1]. Unfortunately, the incidence of severe sepsis is increasing faster than the mortality rate is decreasing, which suggests that current therapies are not effective enough. The key to increasing survival in severe sepsis patients is understanding more about the disease so that newer therapies can be better used, and more successful treatments can be developed. …
Literature
1.
Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR: Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001, 29: 1303-1310. 10.1097/00003246-200107000-00002CrossRefPubMed
Metadata
Title
Re-establishing organ function in severe sepsis: targeting the microcirculation
Author
Jean-François Dhainaut
Publication date
01-08-2005
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 4/2005
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc3752

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