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Critical Care
Published in: Critical Care 4/2004

Open Access 01-08-2004 | Research

Marked elevations in N-terminal brain natriuretic peptide levels in septic shock

Authors: Gerald Chua, Lee Kang-Hoe

Published in: Critical Care | Issue 4/2004

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Abstract

Introduction

N-terminal pro brain natriuretic peptide (NT-proBNP) is a cardiac biomarker that has recently shown to be of diagnostic value in a diagnosis of decompensated heart failure, acute coronary syndromes and other conditions resulting in myocardial stretch. We sought to study whether sepsis-induced myocardial dilation would result in an elevation of NT-proBNP.

Method

Serum NT-proBNP measurements were made in six consecutive patients with septic shock within 6 hours of admission to the intensive care unit.

Results

Markedly elevated levels of NT-proBNP were found in all six patients.

Conclusions

NT-proBNP levels can be markedly elevated in critically ill patients presenting with septic shock. An elevated NT-proBNP level in a critically ill patient is not specific for decompensated heart failure.
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Metadata
Title
Marked elevations in N-terminal brain natriuretic peptide levels in septic shock
Authors
Gerald Chua
Lee Kang-Hoe
Publication date
01-08-2004
Publisher
BioMed Central
Published in
Critical Care / Issue 4/2004
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc2889

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