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Critical Care
Published in: Critical Care 1/2015

Open Access 01-12-2015 | Poster presentation

Elevated basal levels of circulating activated platelets predict ICU-acquired sepsis and mortality: a prospective study

Author: N Layios

Published in: Critical Care | Special Issue 1/2015

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Excerpt

Platelets are now considered to be immune and inflammatory agents as well as key cells in coagulation, and as such have been implicated in the pathophysiology of sepsis [1]. Thrombocytopenia is associated with sepsis severity and poor prognosis, and hyperactivated platelets probably contribute to microvascular thrombosis and organ failure. In the present study, we evaluated platelet activation markers as potential predictive markers of sepsis and of mortality among four commonly encountered populations of patients admitted to ICUs. …
Literature
1.
de Stoppelaar SF, van't Veer C, van der Poll T: The role of platelets in sepsis. Thromb Haemost. 2014, 11: 666-77.CrossRef
Metadata
Title
Elevated basal levels of circulating activated platelets predict ICU-acquired sepsis and mortality: a prospective study
Author
N Layios
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 1/2015
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc14109

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