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Critical Care
Published in: Critical Care 2/2013

01-04-2013 | Review

Ventriculo-arterial decoupling in acutely altered hemodynamic states

Authors: Fabio Guarracino, Rubia Baldassarri, Michael R Pinsky

Published in: Critical Care | Issue 2/2013

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Excerpt

The dynamic interaction between the heart and the systemic circulation allows the cardiovascular system to be efficient in providing adequate cardiac output and arterial pressures necessary for sufficient organ perfusion [1]. The cardiovascular system provides adequate pressure and flow to the peripheral organs in different physiological (rest and exercise) and pathological conditions because of the continuous modulation of the arterial system compliance, stiffness and resistance with respect to left ventricular (LV) systolic performance [2]. Cardiac output is the final result of this dynamic modulation. Because LV stroke volume depends on myocardial contractility and loading conditions (preload and afterload), both cardiac and arterial dysfunction can lead to acute hemodynamic decompensation and shock. According to the underlying pathophysiological mechanisms, altered hemodynamic profiles can be classified as primarily reflecting cardiogenic, hypovolemic, obstructive or distributive shock. …
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Metadata
Title
Ventriculo-arterial decoupling in acutely altered hemodynamic states
Authors
Fabio Guarracino
Rubia Baldassarri
Michael R Pinsky
Publication date
01-04-2013
Publisher
BioMed Central
Published in
Critical Care / Issue 2/2013
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc12522

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