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Published in: Critical Care 6/2012

01-12-2012 | Commentary

Antimicrobial stewardship programs: mandatory for all ICUs

Authors: Marin H Kollef, Scott T Micek

Published in: Critical Care | Issue 6/2012

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Abstract

Antimicrobial stewardship involves a multifaceted approach aimed at combating the emergence of antibiotic resistance, improving patient outcomes, and controlling healthcare costs by optimizing antimicrobial use. Therefore, stewardship is of great importance and relevance in the ICU. The rapid pace of escalating antibiotic resistance and the widespread use of antibiotics in critical care require that stewardship programs be routinely employed in the ICU setting.
Literature
1.
go back to reference Katsios CM, Burry L, Nelson S, Bell CM, Jivraj T, Lapinsky SE, Wax RS, Christian M, Mehta S, Morris AM: An antimicrobial stewardship program improves antimicrobial treatment by culture site and the quality of antimicrobial prescribing in critically ill patients. Crit Care 2012, 16: R216. 10.1186/cc11854PubMedCentralCrossRefPubMed Katsios CM, Burry L, Nelson S, Bell CM, Jivraj T, Lapinsky SE, Wax RS, Christian M, Mehta S, Morris AM: An antimicrobial stewardship program improves antimicrobial treatment by culture site and the quality of antimicrobial prescribing in critically ill patients. Crit Care 2012, 16: R216. 10.1186/cc11854PubMedCentralCrossRefPubMed
2.
go back to reference Lawrence KL, Kollef MH: Antimicrobial stewardship in the intensive care unit: advances and obstacles. Am J Respir Crit Care Med 2009, 179: 434-438. 10.1164/rccm.200809-1394CPCrossRefPubMed Lawrence KL, Kollef MH: Antimicrobial stewardship in the intensive care unit: advances and obstacles. Am J Respir Crit Care Med 2009, 179: 434-438. 10.1164/rccm.200809-1394CPCrossRefPubMed
3.
go back to reference Micek ST, Ward S, Fraser VJ, Kollef MH: A randomized controlled trial of an antibiotic discontinuation policy for clinically suspected ventilator-associated pneumonia. Chest 2004, 125: 1791-1799. 10.1378/chest.125.5.1791CrossRefPubMed Micek ST, Ward S, Fraser VJ, Kollef MH: A randomized controlled trial of an antibiotic discontinuation policy for clinically suspected ventilator-associated pneumonia. Chest 2004, 125: 1791-1799. 10.1378/chest.125.5.1791CrossRefPubMed
4.
go back to reference Arnold HM, Micek ST, Skrupky LP, Kollef MH: Antibiotic stewardship in the intensive care unit. Semin Respir Crit Care Med 2011, 32: 215-227. 10.1055/s-0031-1275534CrossRefPubMed Arnold HM, Micek ST, Skrupky LP, Kollef MH: Antibiotic stewardship in the intensive care unit. Semin Respir Crit Care Med 2011, 32: 215-227. 10.1055/s-0031-1275534CrossRefPubMed
5.
go back to reference Society for Healthcare Epidemiology of America; Infectious Diseases Society of America; Pediatric Infectious Diseases Society: Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol 2012, 33: 322-327.CrossRef Society for Healthcare Epidemiology of America; Infectious Diseases Society of America; Pediatric Infectious Diseases Society: Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol 2012, 33: 322-327.CrossRef
6.
go back to reference Griffith M, Postelnick M, Scheetz M: Antimicrobial stewardship programs: methods of operation and suggested outcomes. Expert Rev Anti Infect Ther 2012, 10: 63-73. 10.1586/eri.11.153CrossRefPubMed Griffith M, Postelnick M, Scheetz M: Antimicrobial stewardship programs: methods of operation and suggested outcomes. Expert Rev Anti Infect Ther 2012, 10: 63-73. 10.1586/eri.11.153CrossRefPubMed
7.
go back to reference Chalfine A, Kitzis MD, Bezie Y, Benali A, Perniceni L, Nguyen JC, Dumay MF, Gonot J, Rejasse G, Goldstein F, Carlet J, Misset B: Ten-year decrease of acquired methicillin-resistant Staphylococcus aureus (MRSA) bacteremia at a single institution: the result of a multifaceted program combining crosstransmission prevention and antimicrobial stewardship. Antimicrob Resist Infect Control 2012, 1: 18. 10.1186/2047-2994-1-18PubMedCentralCrossRefPubMed Chalfine A, Kitzis MD, Bezie Y, Benali A, Perniceni L, Nguyen JC, Dumay MF, Gonot J, Rejasse G, Goldstein F, Carlet J, Misset B: Ten-year decrease of acquired methicillin-resistant Staphylococcus aureus (MRSA) bacteremia at a single institution: the result of a multifaceted program combining crosstransmission prevention and antimicrobial stewardship. Antimicrob Resist Infect Control 2012, 1: 18. 10.1186/2047-2994-1-18PubMedCentralCrossRefPubMed
8.
go back to reference Apisarnthanarak A, Pinitchai U, Thongphubeth K, Yuekyen C, Warren DK, Fraser VJ, Thammasat University Pandrug-Resistant Acinetobacter baumannii Control Group: A multifaceted intervention to reduce pandrug-resistant Acinetobacter baumannii colonization and infection in 3 intensive care units in a Thai tertiary care center: a 3-year study. Clin Infect Dis 2008, 47: 760-767. 10.1086/591134CrossRefPubMed Apisarnthanarak A, Pinitchai U, Thongphubeth K, Yuekyen C, Warren DK, Fraser VJ, Thammasat University Pandrug-Resistant Acinetobacter baumannii Control Group: A multifaceted intervention to reduce pandrug-resistant Acinetobacter baumannii colonization and infection in 3 intensive care units in a Thai tertiary care center: a 3-year study. Clin Infect Dis 2008, 47: 760-767. 10.1086/591134CrossRefPubMed
9.
go back to reference Chung DR, Song JH, Kim SH, Thamlikitkul V, Huang SG, Wang H, So TM, Yasin RM, Hsueh PR, Carlos CC, Hsu LY, Buntaran L, Lalitha MK, Kim MJ, Choi JY, Kim SI, Ko KS, Kang CI, Peck KR, Asian Network for Surveillance of Resistant Pathogens Study Group: High prevalence of multidrug-resistant nonfermenters in hospital-acquired pneumonia in Asia. Am J Respir Crit Care Med 2011, 184: 1409-1417. 10.1164/rccm.201102-0349OCCrossRefPubMed Chung DR, Song JH, Kim SH, Thamlikitkul V, Huang SG, Wang H, So TM, Yasin RM, Hsueh PR, Carlos CC, Hsu LY, Buntaran L, Lalitha MK, Kim MJ, Choi JY, Kim SI, Ko KS, Kang CI, Peck KR, Asian Network for Surveillance of Resistant Pathogens Study Group: High prevalence of multidrug-resistant nonfermenters in hospital-acquired pneumonia in Asia. Am J Respir Crit Care Med 2011, 184: 1409-1417. 10.1164/rccm.201102-0349OCCrossRefPubMed
10.
go back to reference Morata L, Cobos-Trigueros N, Martínez JA, Soriano A, Almela M, Marco F, Sterzik H, Núñez R, Hernández C, Mensa J: Influence of multidrug resistance and appropriate empirical therapy on the 30-day mortality rate of Pseudomonas aeruginosa bacteremia. Antimicrob Agents Chemother 2012, 56: 4833-4837. 10.1128/AAC.00750-12PubMedCentralCrossRefPubMed Morata L, Cobos-Trigueros N, Martínez JA, Soriano A, Almela M, Marco F, Sterzik H, Núñez R, Hernández C, Mensa J: Influence of multidrug resistance and appropriate empirical therapy on the 30-day mortality rate of Pseudomonas aeruginosa bacteremia. Antimicrob Agents Chemother 2012, 56: 4833-4837. 10.1128/AAC.00750-12PubMedCentralCrossRefPubMed
11.
go back to reference George P, Morris AM: Pro/con debate: Should antimicrobial stewardship programs be adopted universally in the intensive care unit? Crit Care 2010, 14: 205. 10.1186/cc8219PubMedCentralCrossRefPubMed George P, Morris AM: Pro/con debate: Should antimicrobial stewardship programs be adopted universally in the intensive care unit? Crit Care 2010, 14: 205. 10.1186/cc8219PubMedCentralCrossRefPubMed
12.
go back to reference Nowak MA, Nelson RE, Breidenbach JL, Thompson PA, Carson PJ: Clinical and economic outcomes of a prospective antimicrobial stewardship program. Am J Health Syst Pharm 2012, 69: 1500-1508. 10.2146/ajhp110603CrossRefPubMed Nowak MA, Nelson RE, Breidenbach JL, Thompson PA, Carson PJ: Clinical and economic outcomes of a prospective antimicrobial stewardship program. Am J Health Syst Pharm 2012, 69: 1500-1508. 10.2146/ajhp110603CrossRefPubMed
13.
go back to reference Schuetz P, Briel M, Christ-Crain M, Stolz D, Bouadma L, Wolff M, Luyt CE, Chastre J, Tubach F, Kristoff ersen KB, Wei L, Burkhardt O, Welte T, Schroeder S, Nobre V, Tamm M, Bhatnagar N, Bucher HC, Mueller B: Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: an individual patient data meta-analysis. Clin Infect Dis 2012, 55: 651-662. 10.1093/cid/cis464PubMedCentralCrossRefPubMed Schuetz P, Briel M, Christ-Crain M, Stolz D, Bouadma L, Wolff M, Luyt CE, Chastre J, Tubach F, Kristoff ersen KB, Wei L, Burkhardt O, Welte T, Schroeder S, Nobre V, Tamm M, Bhatnagar N, Bucher HC, Mueller B: Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: an individual patient data meta-analysis. Clin Infect Dis 2012, 55: 651-662. 10.1093/cid/cis464PubMedCentralCrossRefPubMed
14.
go back to reference Lodes U, Bohmeier B, Lippert H, König B, Meyer F: PCR-based rapid sepsis diagnosis effectively guides clinical treatment in patients with new onset of SIRS. Langenbecks Arch Surg 2012, 397: 447-455. 10.1007/s00423-011-0870-zCrossRefPubMed Lodes U, Bohmeier B, Lippert H, König B, Meyer F: PCR-based rapid sepsis diagnosis effectively guides clinical treatment in patients with new onset of SIRS. Langenbecks Arch Surg 2012, 397: 447-455. 10.1007/s00423-011-0870-zCrossRefPubMed
15.
go back to reference Coates AR, Halls G: Antibiotics in phase II and III clinical trials. Handb Exp Pharmacol 2012, 211: 167-183. 10.1007/978-3-642-28951-4_11CrossRefPubMed Coates AR, Halls G: Antibiotics in phase II and III clinical trials. Handb Exp Pharmacol 2012, 211: 167-183. 10.1007/978-3-642-28951-4_11CrossRefPubMed
Metadata
Title
Antimicrobial stewardship programs: mandatory for all ICUs
Authors
Marin H Kollef
Scott T Micek
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Critical Care / Issue 6/2012
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11853

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