Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Critical Care
Published in: Critical Care 2/2012

Open Access 01-04-2012 | Meeting abstract

Hypothermia after aneurysmal subarachnoid hemorrhage

Authors: Martin Seule, Emanuela Keller

Published in: Critical Care | Special Issue 2/2012

Login to get access

Excerpt

Aneurysmal subarachnoid hemorrhage (SAH) is a common and frequently devastating condition, accounting for 1 to 7% of all strokes with an incidence of 9.1 per 100,000 [1]. Major advances in SAH management over the past three decades have decreased case fatality by 0.8% per year, but it is still 40% and many survivors have long-term disabilities [2]. The most important and potentially treatable complication is development of delayed cerebral ischemia (DCI), which can progress to cerebral infarction associated with poor outcome. …
Literature
1.
Feigin VL, Lawes CM, Bennett DA, Anderson CS: Stroke epidemiology: a review of population-based studies of incidence, prevalence, and case-fatality in the late 20th century. Lancet Neurol 2003, 2: 43-53. 10.1016/S1474-4422(03)00266-7CrossRefPubMed
2.
Nieuwkamp DJ, Setz LE, Algra A, Linn FH, de Rooij NK, Rinkel GJ: Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. Lancet Neurol 2009, 8: 635-642. 10.1016/S1474-4422(09)70126-7CrossRefPubMed
3.
Ostrowski RP, Colohan AR, Zhang JH: Molecular mechanisms of early brain injury after subarachnoid hemorrhage. Neurol Res 2006, 28: 399-414. 10.1179/016164106X115008CrossRefPubMed
4.
Bederson JB, Germano IM, Guarino L: Cortical blood flow and cerebral perfusion pressure in a new noncraniotomy model of subarachnoid hemorrhage in the rat. Stroke 1995, 26: 1086-1091. discussion 1091-1092 10.1161/01.STR.26.6.1086CrossRefPubMed
5.
Vergouwen MD, Ilodigwe D, Macdonald RL: Cerebral infarction after subarachnoid hemorrhage contributes to poor outcome by vasospasm-dependent and -independent effects. Stroke 2011, 42: 924-929. 10.1161/STROKEAHA.110.597914CrossRefPubMed
6.
Rabinstein AA, Weigand S, Atkinson JL, Wijdicks EF: Patterns of cerebral infarction in aneurysmal subarachnoid hemorrhage. Stroke 2005, 36: 992-997. 10.1161/01.STR.0000163090.59350.5aCrossRefPubMed
7.
Muroi C, Seule M, Mishima K, Keller E: Novel treatments for vasospasm after subarachnoid hemorrhage. Curr Opin Crit Care 2012, 18: 119-126. 10.1097/MCC.0b013e32835075aeCrossRefPubMed
8.
Castanares-Zapatero D, Hantson P: Pharmacological treatment of delayed cerebral ischemia and vasospasm in subarachnoid hemorrhage. Ann Intensive Care 2011, 1: 12. 10.1186/2110-5820-1-12PubMedCentralCrossRefPubMed
9.
Erecinska M, Thoresen M, Silver IA: Effects of hypothermia on energy metabolism in mammalian central nervous system. J Cereb Blood Flow Metab 2003, 23: 513-530.CrossRefPubMed
10.
Karibe H, Zarow GJ, Graham SH, Weinstein PR: Mild intraischemic hypothermia reduces postischemic hyperperfusion, delayed postischemic hypoperfusion, blood-brain barrier disruption, brain edema, and neuronal damage volume after temporary focal cerebral ischemia in rats. J Cereb Blood Flow Metab 1994, 14: 620-627. 10.1038/jcbfm.1994.77CrossRefPubMed
11.
Schubert GA, Poli S, Schilling L, Heiland S, Thome C: Hypothermia reduces cytotoxic edema and metabolic alterations during the acute phase of massive SAH: a diffusion-weighted imaging and spectroscopy study in rats. J Neurotrauma 2008, 25: 841-852. 10.1089/neu.2007.0443CrossRefPubMed
12.
Schubert GA, Poli S, Mendelowitsch A, Schilling L, Thome C: Hypothermia reduces early hypoperfusion and metabolic alterations during the acute phase of massive subarachnoid hemorrhage: a laser-Doppler-flowmetry and microdialysis study in rats. J Neurotrauma 2008, 25: 539-548. 10.1089/neu.2007.0500CrossRefPubMed
13.
Muroi C, Frei K, El Beltagy M, Cesnulis E, Yonekawa Y, Keller E: Combined therapeutic hypothermia and barbiturate coma reduces interleukin-6 in the cerebrospinal fluid after aneurysmal subarachnoid hemorrhage. J Neurosurg Anesthesiol 2008, 20: 193-198. 10.1097/ANA.0b013e31817996bfCrossRefPubMed
14.
Hindman BJ, Todd MM, Gelb AW, Loftus CM, Craen RA, Schubert A, Mahla ME, Torner JC: Mild hypothermia as a protective therapy during intracranial aneurysm surgery: a randomized prospective pilot trial. Neurosurgery 1999, 44: 23-32. discussion 32-33 10.1097/00006123-199901000-00009CrossRefPubMed
15.
Karibe H, Sato K, Shimizu H, Tominaga T, Koshu K, Yoshimoto T: Intraoperative mild hypothermia ameliorates postoperative cerebral blood flow impairment in patients with aneurysmal subarachnoid hemorrhage. Neurosurgery 2000, 47: 594-599. discussion 599-601PubMed
16.
Ogilvy CS, Carter BS, Kaplan S, Rich C, Crowell RM: Temporary vessel occlusion for aneurysm surgery: risk factors for stroke in patients protected by induced hypothermia and hypertension and intravenous mannitol administration. J Neurosurg 1996, 84: 785-791. 10.3171/jns.1996.84.5.0785CrossRefPubMed
17.
Sato K, Yoshimoto T: Systemic and cerebral haemodynamics during craniotomy under mild hypothermia in patients with acute subarachnoid haemorrhage. Acta Neurochir (Wien) 2000, 142: 1013-1019. discussion 1019-1020 10.1007/s007010070056CrossRef
18.
Kimme P, Fridrikssen S, Engdahl O, Hillman J, Vegfors M, Sjoberg F: Moderate hypothermia for 359 operations to clip cerebral aneurysms. Br J Anaesth 2004, 93: 343-347. 10.1093/bja/aeh206CrossRefPubMed
19.
Todd MM, Hindman BJ, Clarke WR, Torner JC: Mild intraoperative hypothermia during surgery for intracranial aneurysm. N Engl J Med 2005, 352: 135-145. 10.1056/NEJMoa040975CrossRefPubMed
20.
Anderson SW, Todd MM, Hindman BJ, Clarke WR, Torner JC, Tranel D, Yoo B, Weeks J, Manzel KW, Samra S: Effects of intraoperative hypothermia on neuropsychological outcomes after intracranial aneurysm surgery. Ann Neurol 2006, 60: 518-527. 10.1002/ana.21018CrossRefPubMed
21.
Hindman BJ, Bayman EO, Pfisterer WK, Torner JC, Todd MM: No association between intraoperative hypothermia or supplemental protective drug and neurologic outcomes in patients undergoing temporary clipping during cerebral aneurysm surgery: findings from the Intraoperative Hypothermia for Aneurysm Surgery Trial. Anesthesiology 2010, 112: 86-101. 10.1097/ALN.0b013e3181c5e28fCrossRefPubMed
22.
Kawamura Y, Yamada K, Masago A, Katano H, Matsumoto T, Mase M: Hypothermia modulates induction of hsp70 and c-jun mRNA in the rat brain after subarachnoid hemorrhage. J Neurotrauma 2000, 17: 243-250. 10.1089/neu.2000.17.243CrossRefPubMed
23.
Thome C, Schubert G, Piepgras A, Elste V, Schilling L, Schmiedek P: Hypothermia reduces acute vasospasm following SAH in rats. Acta Neurochir Suppl 2001, 77: 255-258.PubMed
24.
Torok E, Klopotowski M, Trabold R, Thal SC, Plesnila N, Scholler K: Mild hypothermia (33°C) reduces intracranial hypertension and improves functional outcome after subarachnoid hemorrhage in rats. Neurosurgery 2009, 65: 352-359. discussion 359 10.1227/01.NEU.0000345632.09882.FFCrossRefPubMed
25.
Yasui N, Kawamura S, Suzuki A, Hadeishi H, Hatazawa J: Role of hypothermia in the management of severe cases of subarachnoid hemorrhage. Acta Neurochir Suppl 2002, 82: 93-98.PubMed
26.
Anei R, Sakai H, Iihara K, Nagata I: Effectiveness of brain hypothermia treatment in patients with severe subarachnoid hemorrhage: comparisons at a single facility. Neurol Med Chir (Tokyo) 2010, 50: 879-883. 10.2176/nmc.50.879CrossRef
27.
Wang ZP, Chen HS, Wang FX: Influence of plasma and cerebrospinal fluid levels of endothelin-1 and NO in reducing cerebral vasospasm after subarachnoid hemorrhage during treatment with mild hypothermia, in a dog model. Cell Biochem Biophys 2011, 61: 137-143. 10.1007/s12013-011-9170-zCrossRefPubMed
28.
Nagao S, Irie K, Kawai N, Kunishio K, Ogawa T, Nakamura T, Okauchi M: Protective effect of mild hypothermia on symptomatic vasospasm: a preliminary report. Acta Neurochir Suppl 2000, 76: 547-550.PubMed
29.
Nagao S, Irie K, Kawai N, Nakamura T, Kunishio K, Matsumoto Y: The use of mild hypothermia for patients with severe vasospasm: a preliminary report. J Clin Neurosci 2003, 10: 208-212. 10.1016/S0967-5868(02)00322-3CrossRefPubMed
30.
Nakamura T, Tatara N, Morisaki K, Kawakita K, Nagao S: Cerebral oxygen metabolism monitoring under hypothermia for severe subarachnoid hemorrhage: report of eight cases. Acta Neurol Scand 2002, 106: 314-318.CrossRefPubMed
31.
Seule MA, Muroi C, Mink S, Yonekawa Y, Keller E: Therapeutic hypothermia in patients with aneurysmal subarachnoid hemorrhage, refractory intracranial hypertension, or cerebral vasospasm. Neurosurgery 2009, 64: 86-92. discussion 92-93 10.1227/01.NEU.0000336312.32773.A0CrossRefPubMed
Metadata
Title
Hypothermia after aneurysmal subarachnoid hemorrhage
Authors
Martin Seule
Emanuela Keller
Publication date
01-04-2012
Publisher
BioMed Central
Published in
Critical Care / Issue Special Issue 2/2012
Electronic ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc11274

Other articles of this Special Issue 2/2012

Critical Care 2/2012 Go to the issue

Meeting abstract

Temperature management in central nervous infection

Meeting abstract

Rewarming: facts and myths from the systemic perspective

Meeting abstract

Intracranial pressure and hypothermia

Meeting abstract

Standard operating procedures: therapeutic hypothermia in CPR and post-resuscitation care

Meeting abstract

In-hospital hypothermia

Meeting abstract

Pathogenetic mechanisms of heatstroke and novel therapies