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01-08-2000 | Commentary

Utilization of human tissue in breast cancer research

Authors: Wendy Prime, Mark E Sobel, C Simon Herrington

Published in: Breast Cancer Research | Issue 4/2000

Abstract

The use of human tissue, and material derived from such tissue, for research purposes is currently the subject of much debate. This debate needs to address several issues, including: the principle of abandonment; the distinction between identified and unidentified specimens; general versus specific informed consent; and, with the improvement in biotechnology and medical informatics, the design and security of research databases. The outcome of this debate will shape the way in which research studies using human biological materials are designed and executed.

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National Bioethics Advisory Commission: Research Involving Human Biological Materials: Ethical Issues and Policy Guidance, vol 1. Rockville, MD: US Government Printing Office. [http://bioethics.gov/pubs.html]

Grizzle W, Grody WW, Nol WW, et al: Recommended policies for uses of human tissue in research, education, and quality control. Arch Pathol Lab Med. 1999, 123: 296-300.PubMed

Medical Research Council: Human Tissue and Biological Samples for Use in Research: Report of the Medical Research Council Working Group to Develop Operation and Ethical Guidelines, November 1999. London, UK: Medical Research Council, 1999. [http://www.mrc.ac.uk/templates/images/tissues.html]

Medical Research Council: Personal Information in Medical Research: Draft MRC Guidelines, September 1999. London, UK: Medical Research Council, 1999. [http://www.mrc.ac.uk/Per_info.html]

Royal College of Pathologists: Consensus Statement of Recommended Policies for the Uses of Human Tissue in Research, Education and Quality Control. London, UK: Royal College of Pathologists, 1999. [http://www.rcpath.org]

Nuffield Council on Bioethics: Human Tissue: ethical and legal issues. April 1995. London: Nuffield Foundation. Conclusions and recommendation available on the Web. [http://nuffield.org.uk/bioethics/publication/pub0006740.html]

Taube SE, Barr P, LiVolsi V, Pinn VW: Ensuring the availability of specimens for research. Breast J. 1998, 4: 391-395. 10.1046/j.1524-4741.1998.450391.x.CrossRef

Title: Utilization of human tissue in breast cancer research
Authors: Wendy Prime
Mark E Sobel
C Simon Herrington
Publication date: 01-08-2000
Publisher: BioMed Central
Published in: Breast Cancer Research / Issue 4/2000
Electronic ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr61

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